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Future of Everything
Future of Everything

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The Next Frontier to Treat Cancer: Electricity

PHOTO ILLUSTRATION: DAISY KORPICS FOR WSJ/GETTY (2)

For decades, electricity has played a role in medicine, through pacemakers that have delivered electric pulses to keep heartbeats steady and electroconvulsive therapy that has helped people with serious mental illness after other treatments failed.

Today, new technologies and devices are widening the scope of how electric fields and pulses could be used as medicine.

This week, Brianna Abbott reports on how biotech companies and researchers are developing ways to use electricity to treat diseases from rheumatoid arthritis to pancreatic cancer.

Novocure, an oncology company, has developed technology that uses low-intensity electric fields to disrupt the electrical forces at play in cell division to slow down tumor growth.

The company’s system—which consists of adhesive patches that contain electrodes and a battery pack—is approved by the FDA for patients with glioblastoma, an aggressive brain cancer.

“We’re leveraging the electrical properties of cancer cells. We think about bodies as being biological beings or as chemical beings, but we also are electrical beings.”

— Ashley Cordova, CEO Novocure

A similar Novocure device is also used to treat mesothelioma, and was approved for some lung cancer patients late last year. 

Separately, researchers are developing tiny pacemakers for newborn babies who have heart defects, and seeing whether electrical stimulation to a person’s spinal cord can help treat depression.

More on this topic:

  • OpenAI expanded its healthcare push with Color Health’s cancer copilot. (Read)
  • The hologram doctor will see you now. (Read)
  • Reid Hoffman raised $24.6 million for an AI cancer-research startup. (Read)

🤔 Would you consider newly developed medical treatments that use electricity? Why or why not? Send me your thoughts, questions and predictions by hitting "reply" to this email.

 
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Hear From Leaders Across Business, Tech and Beyond at The Future of Everything

The Wall Street Journal newsroom has confirmed new speakers to join the lineup for our premier live event, The Future of Everything, taking place May 28–29 at The Glasshouse in New York City. Hear interviews from these global newsmakers as they contend with the future from the authority of their unique vantage points.

  • Russlynn Ali, Co-Founder and CEO, XQ Institute
  • Jeremy Bloom, CEO, X Games; Two-Time Olympian
  • Christopher Boerner, Chair and CEO, Bristol Myers Squibb
  • Scott Kirby, CEO, United Airlines

Enjoy an exclusive 20% subscriber discount. Request your invitation here.

 

More of What’s Next: Squishy Robots; A Crispr Success; China's "Invasion Platforms"

PHOTO: ISABELLE BOUSQUETTE/WSJ

Worms and turtles are inspiring new "squishy" robots at MIT. Daniela Rus, the director of MIT’s Computer Science and Artificial Intelligence Lab, is developing robots that take more cues from nature than science fiction—including soft, flexible and even edible designs.

PHOTO: MULDOON FAMILY

A gene-editing breakthrough saved an infant with a rare disease. K.J. Muldoon was treated with a customized Crispr gene-editing therapy for a deadly metabolic disease. Doctors say the treatment could be used as a template to create individualized treatments quickly for other patients with rare diseases.

PHOTO ILLUSTRATION: WSJ

China’s new “invasion platforms” can land on beaches and link to form massive mobile piers. Analysts say the amphibious ships are intended to rapidly offload military equipment, potentially setting the stage for an invasion of Taiwan.

 

🎧 Podcast: Apple Embraces Brain-Implant Technology to Control Devices

Apple wants to make iPhones more accessible to people with disabilities. Digital-health reporter Rolfe Winkler takes us into the world of brain-computer interfaces.

Listen Now
 

Future Feedback

On Tuesday, longevity researcher Dr. Eric Topol joined WSJ health reporters to answer questions from subscribers. Here are a few of his responses:

Q: What are some accessible and practical ways to prioritize health and longevity to become a ‘Super Ager’?

  • “The good news is that most of the practical ways to extend healthspan are free or very low cost. For nutrition, the main goal is to reduce ultraprocessed foods that promote body-wide inflammation—that can be achieved by reading labels and avoiding foods with long lists of ingredients that are things you would not have in your kitchen. Exercise, even without going to any extreme, is remarkably powerful for promoting healthspan.”

Q: How can I get more deep sleep?

  • “This is very important since it’s during deep sleep we clear metabolic waste products from our brain; as we get older, our deep sleep tends to decrease. Deep slow wave sleep is very much influenced by what we eat, when we eat, how we exercise, when we exercise, alcohol, stress, regularity (going to bed at the same time each night), bedroom temperature and darkness, etc. Everyone is different as far as what are key influencing factors. We can track deep sleep through smartwatches or rings and use that data to learn what factor(s) help or hurt your deep sleep. That has helped me considerably. But, as I point out in my book, we don’t have studies that show increasing deep sleep improves outcomes such as less neurodegenerative disease—only that the risk of low deep-sleep time correlates with increased risk. So it’s intuitive, but not yet proven.”

(Responses have been condensed and edited.)

 

Elsewhere in the Future

  • These startups think zeppelins could be the future of air travel. (The Washington Post)
  • Inside the elite Microsoft unit constantly working to thwart hackers. (Bloomberg)
  • Montana is on track to be the first U.S. hub for experimental medical treatments. (MIT Technology Review)
 

About Us

Thanks for reading The Future of Everything. We cover the innovation and tech transforming the way we live, work and play. This newsletter was written by Conor Grant. Get in touch with us at future@wsj.com.

See more from The Future of Everything at wsj.com/foe.

 
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