No images? Click here Click here to subscribe to the daily brief. September 9, 2020 - Brief Issue 90 The Coronavirus Daily Brief is a daily news and analysis roundup edited by New America’s International Security Program and Arizona State University. Subscribe or listen here to get the top weekly stories as a podcast at the start of each week. Top Headlines United States Sees Increase in Coronavirus Cases Across 22 States; Fauci Says U.S. Needs to Get Daily Case Number Down to 10,000; Universities and College Towns See Surges in Local Coronavirus Cases (Health & Science) NIH Distributes $129.3 Million of Its $2.5 Billion Sum for Coronavirus Tests; U.S. Pivots on Efforts to Produce Viable Rapid Tests (Health & Science) New Study Highlights Bridge Between Obesity and Severe COVID-19 (Health & Science) Vaccine Makers Pledge to Uphold Vaccine Safety Amid Concerns About Pressure to Approve a Vaccine before November Election; Warp Speed Scientific Head Says Sufficient Data for Approval Unlikely by End of October (Health & Science) In the Lab, Coronavirus Appears to Slice Heart Muscle Fibers, Adding to Growing Evidence That COVID-19 Can Attack the Heart (Health & Science) Germany Sees Highest Daily Increases in Infections Since April (Around the World) Sweden Sees Lowest New Infection Rate Since Beginning of Pandemic (Around the World) Belarusian Prime Minister Receives Russian Vaccine (Around the World) India Overtakes Brazil as Second Worst-Hit Nation (Around the World) 14 Vietnamese Soldiers Return Coronavirus Positive From Russian Army Games (Around the World) Jordan Experiences First Coronavirus Cases in Syrian Refugee Camps (Around the World) Senate Returns From August Recess; Little Evidence of Forthcoming Coronavirus Aid Deal (U.S. Government & Politics) USAID Coronavirus Task Force to Shut Down (U.S. Government & Politics) Mortgage Market Booms Despite Virus-Driven Economic Troubles (U.S. Economy) Coronavirus Fears as Students Return to School (U.S. Society) Conspiracies and Lack of Response Hampering Contact Tracing (U.S. Society) Health & Science There have been 6,328,051 coronavirus cases in the United States, and 189,680 people have died (Johns Hopkins). Around 2,359,111 people have recovered, and the United States has conducted 83,964,567 tests. Worldwide, there have been 27,598,479 confirmed cases of coronavirus, with 898,020 deaths. At least 18,559,460 people have recovered from the virus. According to a report by Reuters on Sunday, coronavirus cases in the United States are rising in 22 U.S. states. Three weeks prior, cases were increasing in only three U.S. states. For example, South Dakota saw the largest increase in confirmed new cases, up 126 percent to 3,700. This may be in large part to a motorcycle rally with nearly 500,000 participants that took place in the state in August, which one analysis suggests was a superspreader event that may have generated over 250,000 new cases and over $12 billion in public health costs (IZA Institute of Labor Economics). Iowa and North Dakota are two other states with sharp increases in the last two weeks, with 13,600 and 3,600 new infections respectively. A wedding in Maine that took place on August 7 has resulted in 147 infections and at least three deaths. Sixty-five people attended the wedding, 15 more than the state’s 50-person limit for indoor gatherings. At the end of the month, a little over 50 coronavirus cases were reported as a result of the wedding. Now, a little more than one week later, there were nearly 150 (NBC News). The three Maine residents who have died as a result were not attendees. NIH Distributes $129.3 Million of Its $2.5 Billion Sum for Coronavirus Tests; U.S. Pivots on Efforts to
Produce Viable Rapid Tests Vaccine Makers Pledge to Uphold Vaccine Safety Amid Concerns About Pressure to Approve a Vaccine before November Election; Warp Speed Scientific Head Says Sufficient Data for Approval Unlikely by End of October In a highly unusual public letter on Tuesday, the CEOs of nine major pharmaceutical companies pledged to “uphold the integrity of the scientific process” and “always make the safety and well-being of vaccinated individuals our top priority.” Specifically, they agreed not to seek emergency use authorization from the U.S. Food and Drug Administration (FDA) for their coronavirus vaccines before they have completed their Phase III clinical trials (Bloomberg, Bloomberg, CNN, Hill, NPR, NYT, WaPo, WSJ). Last week, BIO, the biopharmaceutical industry group signed a similar open letter that also called for “[o]ur nation’s leaders” to “reassure the public that politics will not influence the development and approval of new medicines.” These moves follow President Trump’s push for an authorized vaccine before the November 3 election date (WaPo), his claim that “deep state” elements at the FDA are delaying vaccines until after the election (Twitter), and public concerns that the FDA may yield to political pressure to authorize a vaccine (STAT). “It’s unprecedented in my experience that industry would do something like this,” pharmaceutical industry watcher Ira Loss of Washington Analysis told STAT. “But we’ve experienced unprecedented events since the beginning of COVID-19, starting with the FDA, where the commissioner has proven to be malleable, to be kind, at the foot of the president.” FDA Commissioner Stephen Hanh raised concerns when he told the Financial Times last month that the FDA was prepared to authorize a vaccine before the Phase III clinical trials were complete (FT). While Hahn has said that he will not yield to political pressure, the FDA authorized Trump’s much-touted drug hydroxychloroquine on what scientists have called thin evidence and then later withdrew authorization in the face of accumulating evidence that the drug was ineffective. Similarly, President Trump has inaccurately hailed convalescent plasma as a medical success and the FDA has granted a controversial emergency use authorization which has drawn criticism from former senior FDA officials (BioCentury) and the National Institutes of Health (NIH). NIH’s COVID-19 Treatment Guidelines Panel advised that convalescent plasma “should not be considered standard of care” because there was “insufficient data to recommend either for or against the use of convalescent plasma for the treatment of COVID-19” (BioCentury). The FDA authorization relied on a study whose results Hahn overstated and later recanted unofficially, saying the “criticism is entirely justified” on Twitter but not in an official statement. Of the nine companies who signed the vaccine safety pledge, four have vaccine candidates in Phase III trials in the United States: one vaccine candidate each by Moderna; Pfizer with BioNTech; and AstraZeneca with Oxford University. On Tuesday, AstraZeneca halted its clinical trials worldwide to investigate a serious illness in one participant; it is unclear whether the illness is related to the vaccine (NYT, STAT). Pfizer Chairman and CEO Albert Bourla said Thursday, “We will not cut corners.... If we have any doubts from the Phase III study, we will not submit either for approval or for authorization” (BioCentury). The other companies who signed the pledge are Merck, Sanofi, GlaxoSmithKline, Johnson & Johnson, and Novavax. Estimating the chances of a vaccine before November, Moncef Slaoui, the scientific head of Operation Warp Speed, told NPR in an interview last week, “There is a very, very low chance that the trials that are running as we speak could read before the end of October” (NPR). The comments came as Trump has repeatedly suggested that a vaccine would be available by October, contrary to health officials’ views (Politico). In a press briefing on Friday, for example, Trump commented that the U.S. might have a vaccine “before the end of the year and maybe even before Nov. 1. I think we can probably have it sometime in October.” Slaoui said “there is no intent” to file for an emergency use authorization “before a demonstration of efficacy and safety in the Phase III trials.” Describing the process, he said the trials “will be completed when an independent data safety monitoring board looks into the data, and they are, of course, separate from the operation, from the NIH, from the government, from everyone involved.” Slaoui estimated that “We may have enough vaccine by the end of the year to immunize probably, I would say, between 20 and 25 million people,” with “enough vaccine to immunize the U.S. population by the middle of 2021” based on plans for ramping up production and distribution. Bonus Reads: “Leader of U.S. Vaccine Push Says He’ll Quit if Politics Trumps Science” (Science); “Operation Warp Speed Promised to do the Impossible. How Far Has it Come?” (STAT); “Why COVID-19 Vaccines Need to Prioritize ‘Superspreaders’” (Conversation). In the Lab, Coronavirus Appears to Slice Heart Muscle Fibers, Adding to Growing Evidence That COVID-19 Can Attack the Heart In studies in lab dishes, the SARS-CoV-2 virus appears to dice up the long fibers in cardiac muscle that allow the heart to contract, scientists at Gladstone Institutes in San Francisco reported in a preprint manuscript (bioRxiv). COVID-19 causes cardiac problems in up to 50 percent of patients, they wrote, but the mechanism was not clear. A growing body of evidence shows that COVID-19 can cause long-term heart problems (Arstechnica), including reports that athletes are suffering from COVID-19 related cardiac problems (Scientific American). A German study found that 78 percent of recovered COVID-19 patients had cardiac involvement or inflammation (JAMA); while the JAMA paper has been amended, its main conclusions still hold. The Gladstone research sheds a possible new light on the subject, showing that in the lab, the virus left the fibers in cardiac muscle looking as if they were surgically sliced. The damage looked like “carnage,” said co-author Bruce Conklin, adding, “Nothing that we see in the published literature is like this in terms of this exact cutting and precise dicing. We should think about this as not only a pulmonary disease, but also potentially a cardiac one” (STAT). While preprint manuscripts do not have the benefit of peer review by experts in the field, who can often point out flaws or areas for revision, preprints are an important vehicle for getting new information out quickly, if sometimes imperfectly. “When we saw this disruption in those microfibers… that was when we made the decision to pull the trigger and put out this preprint,” said co-author Todd McDevitt. “I’m not a scientist who likes to stoke these things [but] I did not sleep, honestly, while we were finishing this paper and putting it out there” (STAT). The scientists found damage in autopsy samples that was similar to but not as severe as the damage they saw in the lab, and they call for further post-mortem research. They also call for high-throughput screening of available drugs that might be of benefit and hope their work will help lead to new drug discoveries, possibly targeting the as yet unknown enzyme that slices through the muscle fibers. Meanwhile, doctors can test COVID-19 patients for heart problems through MRIs and a test for a protein called troponin, which is released by damaged cardiac tissue.
Around the World Europe Germany Sees Highest Daily Increases in Infections Since April Germany’s daily count of new coronavirus infections on Tuesday morning reached its highest level since April at 1,898 new cases. As is the case elsewhere in Europe, Germany has seen an uptick of new cases since August as social gatherings increase and travelers return from abroad amid relaxed restrictions. Chancellor Angela Merkel has ruled out new easings of public health measures as she warned that the situation will likely get worse. Public opinion polls in Germany have shown majority support for social distancing and hygiene rules despite well-publicized anti-lockdown protests in major cities. Despite the new rise, daily infections are still far lower than the almost 7,000 new cases experienced in late March. Germany’s total case count currently stands at 254,957 cases, with 9,409 deaths (Bloomberg). Sweden Sees Lowest New Infection Rate Since Beginning of Pandemic Swedish health officials reported that last week’s testing had a 1.2 percent positive rate, the lowest since the start of the pandemic, as the virus surges elsewhere in Europe. With 1,300 new infections discovered in last week's 120,000 tests, Sweden now has the lowest rate of spread in Scandinavia. Sweden’s high death rate and lax approach to the pandemic has for months spawned controversy both at home and abroad as public health authorities have from the beginning declined to implement a lockdown. With 5,838 dead since the pandemic’s start, its death toll has been proportionately several times greater than other Scandinavian nations. Jonas Ludvigsson, professor of epidemiology at Karolinska Institutet, told Reuters that Swedes likely have a higher level of immunity than other countries due to the government’s approach (Reuters). Such proclamations in the past have been controversial, and government administered studies conducted over the summer suggested that only six percent of Swedes have COVID-19 antibodies (BBC). England to Ban Gatherings Of More Than Six People The English government on Tuesday announced a ban of all gatherings of more than six people in an attempt to avoid a SARS-CoV-2 resurgence. While current rules already limit gatherings to six, a vaguely defined-exemption intended for occasional gatherings such as community events and weddings has allowed for up to 30 people. With police effectively unable to enforce the nominal ban on gatherings of more than six, government officials have complained that the exemptions were being abused. When the tightened rules go into effect on Monday, it will apply to all public and private places as well as to all age groups. Gatherings will still be allowed, however, for professional and educational purposes as well as for organized sports and weddings. Rules in Scotland, Wales, and Northern Ireland thus far remain unchanged (Guardian). Belarusian Prime Minister Receives Russian Vaccine A spokeswoman for Belarusian Prime Minister Roman Golovchenko said on Monday that her boss received a controversial Russian vaccine for COVID-19. Golovchenko, who is nominally Belarus’ head of government but a de-facto deputy to the president, reportedly felt fine after receiving the vaccine, known as Sputnik V, on Thursday. Plans for the inoculation had previously been announced by Russian Prime Minister Mikhail Mishustin during a meeting with Belarusian President Alexander Lukashenko (TASS). Sputnik V was approved for use within Russia in August despite still being in the early phases of testing. Experts around the world have derided the vaccine’s quick turnaround, arguing that it was declared safe and effective far too early in the trials. The Russian Health Ministry announced on Monday that the first batch of the vaccine has entered into public circulation (Al Jazeera). Belarus, which has reported 73,208 cases and 721 deaths, has imposed virtually no public health restrictions in response to the pandemic. President Lukashenko has described the global reaction as “psychosis,” arguing that the virus can perhaps be cured with home remedies such as a hot sauna or vodka. He reportedly tested positive for the virus over the summer without showing major symptoms (VOA). Asia-Pacific India Overtakes Brazil as Second Worst-Hit Nation India overtook Brazil on Monday to become the country with the second-highest number of coronavirus infections amid fears that it will overtake the U.S. to take first place. With around 80,000 new cases reported every day, India is currently seeing the pandemic spread faster within its borders than any other country in the world. Experts widely believe the official number of cases is an undercount as the virus spreads through underserved rural communities in the country of 1.3 billion people. While the government imposed a nationwide lockdown in March, it began lifting restrictions in June as millions of impoverished city dwellers struggled to survive with neither work nor safety nets. The resulting exodus of urban migrants back to their home villages after public transportation resumed has only exacerbated the pandemic’s spread in the countryside (Bloomberg). In the past month, the total case count doubled from two to four million. India’s GDP plunged 23.9 percent in the first quarter of 2020 compared to the previous year, making it the world’s worst-affected national economy amid the pandemic (CBS). Xi Honors “People’s War” Against Pandemic Chinese President Xi Jinping honored the fallen “heroes” in the “people’s war” against COVID-19 at a ceremony on Tuesday in a speech at the Great Hall of the People in Beijing. In spite of criticism from the U.S. and elsewhere that China was slow to respond in the pandemic’s crucial early phases, Xi’s defiant speech took credit for saving tens of millions of lives around the world through early action. The speech shifted focus toward economic recovery, applauding China as the first major economy to return to growth amid the pandemic. Xi also awarded Zhong Nanshan, the public health official at the center of China’s response, the Order of the Republic, the country’s highest honor for Chinese citizens. China, where the novel coronavirus first emerged late last year in the city of Wuhan, has come under criticism abroad for covering up the virus’ existence in its early stages and then later downplaying its significance. Li Wenliang, a Wuhan doctor who died of COVID-19 in February, was reportedly called in for questioning by police and forced to sign a confession in early January for publishing “untrue” information after his early warnings of the new disease went public on social media (Reuters). 14 Vietnamese Soldiers Return Coronavirus Positive From Russian Army Games Vietnam has isolated 14 soldiers after they tested positive for the coronavirus upon their return from the Russia-organized 2020 International Army Games. The soldiers, who had competed at the games at venues in Armenia, Azerbaijan, Belarus, and Uzbekistan from August 23 to September 5, are currently in quarantine at the National Hospital for Tropical Diseases in Hanoi. The hospital is also quarantining 11 other members of the delegation, whose tank crew was the Group 2 champion team in the Tank Biathlon. Vietnam has almost entirely shut its borders, with commercial air traffic in and out of the country shut down since April 1. The country has been largely successful in containing the pandemic, with no community spread reported for a 99-day period until a resurgence was detected in July. Hanoi and Ho Chi Minh City, the country’s two largest cities, have currently been free of community spread for 23 days and 37 days respectively. The total case count stands at 1,054 with 35 deaths (VNExpress). Middle East Jordan Experiences First Coronavirus Cases in Syrian Refugee Camps The first two cases of the coronavirus diagnosed at a Syrian refugee camp in Jordan were reported on Tuesday by the UN Refugee Agency. Both cases were detected at the Azraq camp, which houses 40,000 of the 650,000 Syrians refugees in Jordan who have fled the almost decade-long war in Syria. The UN High Commissioner for Refugees (UNHCR) also announced that all those living with or near the two refugees have been isolated at a center within the camp as health workers trace and test those whom the patients may have come in contact with. The diagnoses have raised concerns that spread of the virus within the camps would be devastating owing to poor sanitation conditions and inability to socially distance. Around 120,000 Syrians are living inside refugee camps in Jordan, with the rest living outside the camps’ perimeters. Four refugees living outside the camps previously tested positive, with three recovering. Jordan has reported 2,478 cases and 17 related deaths since the beginning of the pandemic (Al Jazeera).
U.S. Government & Politics Senate Returns From August Recess; Little Evidence of Forthcoming Coronavirus Aid Deal On Tuesday, the U.S. Senate returned from its August recess, but there is little evidence that it will be able to strike a deal on further coronavirus-related economic aid (Politico). As Politico writes, the Senate has “only days to reach a deal before lawmakers head back home to campaign.” Senate Majority Leader Mitch McConnell (R-KY) has been seeking to organize support for a narrow aid package. Politico writes, “The $500 billion-plus proposal includes $300-per-week federal unemployment payments on top of regular state benefits, another round of funding to aid small and medium-sized businesses, liability protections for businesses, schools and charities, and $105 billion for education, among other provisions.” Yet, it is not clear that McConnell can even gather 51 Republican votes let alone get Democratic support for the package. Democrats are seeking at least $2 trillion in the next aid package and are threatening to block a vote on any other plan that comes to the floor this week. USAID Coronavirus Task Force to Shut Down The U.S. Agency for International Development’s (USAID) Coronavirus Task Force is scheduled to shut down on Wednesday, according to an internal note sent to staffers and reported upon by Politico (Politico). The note read, “As we approach the deactivation of the Task Force on Sept. 9, the entire team is focused on ensuring a smooth transition of key functions back to Bureaus and Independent Offices.” Politico reports, “The decision to end the task force also comes as President Donald Trump and his aides downplay the pandemic in the run-up to November’s elections.” The task force will reportedly hand responsibilities over to other agencies, and a USAID spokesperson said that a new “Readiness Unit” would aid with the transition. USAID had worked on the distribution of American coronavirus aid for other countries. U.S. Economy Mortgage Market Booms Despite Virus-Driven Economic Troubles Even as the broader U.S. economy continues to struggle, the U.S. mortgage market “recorded its best quarter in years this spring,” according to the Wall Street Journal (WSJ). Home loans totaling $1.1 trillion were issued by lenders between April and June 2020, according to data from Black Knight, a mortgage data firm. That represents the highest level of lending since Black Knight began keeping records in 2000. According to the Journal, while many Americans struggle to pay rent and worry about eviction, “many wealthier Americans with steady jobs, stuck at home with fewer places to spend money, are faring well. The pandemic and record-low rates have nudged many of them to buy second homes in more-rural areas or to shop for houses with more space” helping to drive up lending. Home sales rose 25 percent in July 2020, the largest increase on record. However, Ralph McLaughlin, the chief economist at the home-finance startup Haus, warns “This boom in mortgage originations isn’t necessarily going to be that awesome for the broader economy.” Coronavirus Pandemic Hits Vulnerable Farm Workers The coronavirus pandemic is impacting America’s farmworkers, about half of whom are believed to be undocumented immigrants, challenging the Trump administration’s policies on immigration, according to a report in Politico on Tuesday (Politico). Politico writes, “For several weeks, many of the places that grow the nation’s fruits and vegetables have seen disproportionately high rates of coronavirus cases — a national trend that, as harvest season advances in many states, threatens already vulnerable farmworkers, their communities and the places they work.” For example, California’s Imperial County has the state’s highest per capita coronavirus rate of 5,930 cases per 100,000 people and is home to a “fertile valley that grows vast quantities of vegetables as well as melons and chili peppers.” Politico reports that advocates and others worry that the administration’s harsh rhetoric on immigration has made it more difficult to prevent the pandemic’s spread among the farmworker population. JPMorgan Probes Misuse of Coronavirus Funds On Tuesday, JPMorgan Chase & Co. said it would probe misuse of coronavirus relief funds by its employees in a memo sent to staff by the company’s senior leadership (Bloomberg). The memo mentioned “instances of customers misusing Paycheck Protection Program Loans, unemployment benefits and other government programs” adding, “employees have fallen short, too.” The memo noted some of the activity may have been illegal. U.S. Society Coronavirus Fears as Students Return to School On Tuesday, more than 1.8 million American students returned to school amid debates and concerns over safety of in-person schooling and effectiveness of alternatives (CNN). The largest school districts are generally operating entirely online but some districts are open for in-person classes. According to the American Academy of Pediatrics and the Children's Hospital Association, as of August 27, more than 476,000 children have been infected with the novel coronavirus, and the number jumped by 70,330 in the last two weeks of their study, a time period that also saw many school children returning to class. Bonus Read: “It’s Not Easy to Get a Coronavirus Test for a Child,” (NYT). Conspiracies and Lack of Response Hampering Contact Tracing Conspiracy theories and an overall lack of responsiveness are hampering contact tracing efforts across the United States (Politico). Politico writes, “Contact tracing data provided to POLITICO shows more than three-quarters of people interviewed in hard-hit states like California and Louisiana refused to cooperate with efforts to identify relatives or acquaintances who may have been exposed to the disease.” Kirstin Short, bureau chief of epidemiology at the Houston Health Department, commented, “We’ve had people worry that we’re the FBI or other government agencies.” Lori Freeman, chief executive officer of the National Association of County and City Health Officials, told Politico, “The more you begin to politicize the public health part of this response, the more likely it is that you will come up against some really strong public opinion about what it is you are trying to do.” Some conspiracies have suggested that tracing is part of an effort to impose gun control. Legislation penned by Representative Bobby Rush (D-IL) to help fund contact tracing efforts has received criticism conspiracy theorists who assert its an effort to force Americans into quarantine and even as some QAnon followers assert that the bill H.R. 6666 (116) is part of a Satanic conspiracy. Bonus Read: “The Opioid Crisis, Already Serious, Has Intensified During Coronavirus Pandemic,” (WSJ). Analysis & Arguments Contrary to expectations, the pandemic has challenged authoritarian systems, argues Ivan Krastev (NYT). Lyra Walsh Fuchs writes on the rise of tele-health during the pandemic (Dissent). Amanda Mull explores the impact of losing the ability to go to the gym during the pandemic (Atlantic). Bryce Covert writes on the delay and denial of workers comp claims during the pandemic (Intercept). New America Fellow Daniela J. Lamas explores convalescent plasma therapies for COVID-19 patients (NYT). Nature highlights three questions scientists are looking for answers to as they relate to the novel coronavirus. STAT outlines how the pandemic plays with a person’s perception of time.
Readers can send in tips, critiques, questions, and suggestions to coronavirusbrief@newamerica.org. The Brief is edited by Melissa Salyk-Virk and David Sterman and co-edited by Emily Schneider and Narisara Murray, and Bennett Murray with Brianna Kablack and Senior Editor Peter Bergen. Read previous briefs here and stream and subscribe to our weekly podcast here. About New America New America is dedicated to renewing the promise of America by continuing the quest to realize our nation's highest ideals. Read the rest of our story, or see what we've been doing recently in our latest Annual Report. Help us to continue advancing policy solutions and journalism by making a donation to New America. |