A prospective study authored by Joshua Hill and Danielle Zerr determined that higher than average HHV-6B DNA levels increased the odds of developing delirium after cord blood transplantation (CBT) by almost three fold. Patients with DNA loads in the top quartile had a 4.5 fold increase in delirium. The authors point out that HHV-6B DNA may not always be detectable in liquid compartments such as plasma and cerebrospinal fluid at the time of delirium symptoms.The study also demonstrated that intensified antiviral prophylaxis with ganciclovir and valacyclovir may mitigate HHV-6B reactivation. READ MORE