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RESIDENCY NEWS

 

DIDACTIC PEARLS

Graduating class at Winter Retreat, 2012

 

Anaphylaxis
Jonathan Davis, MD

  • Cutaneous findings can be absent in up to 15% of cases of anaphylaxis
  • Consider and document symptom trajectory in your reasoning to give (or not give) epinephrine
  • Treatment guidelines recommend intramuscular epinephrine (preferably in lateral thigh) over subcutaneous epinephrine

The diagnosis and management of anaphylaxis practice parameter: 2010 update. J Allergy Clin Immunol 2010;126:3:477.
Cydulka R, Davison D, Grammer L et al. The use of epinephrine in the treatment of older adult asthmatics. Ann Emerg Med 1988; 17:4:322-6.

Evidence Based Anecdotes
Munish Goyal, MD

  • Oxygen and IVF are drugs. Only use as much as you need.
  • Guide resuscitation with endpoints, usually a combination of gross (mental status), physiologic (HR, MAP) and laboratory (Lactate) markers.
  • Consider using BiPAP for 3+ minutes pre-intubation to increase PaO2 for hypoxemic patients who require intubation.
  • If you are going to cool a patient post-arrest, initiate ASAP. Also, titrate down the FiO2 to maintain an SpO2 around 96%.

Bickell WH, Wall MJ, et al.  Immediate versus delayed fluid resuscitation for hypotensive patients with penatrating torso trauma.  NEJM. Vol 331;17.  1994. 1105-9.   
Balan IS, Fiskum G, et al.  Oximetry-guided reoxygenation improves neurologic outcomes after experimental cardiac arrest.  Stroke.  2006, Dec.  37(12). 3008-13. 
Che D, Li L, et al.  Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest.  Critical Care Med, 2011.  39(6).  1423-30.   
Kilgannon JH, Jones AE, et al.  Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality.  JAMA, 2010.  303(21).  2165-71. 
Baillard C, Fosse JP, et al.  Noninvasive ventilation improves preoxygenation before intubation of hypoxic patients.  American Journal of Respiratory and Critical Care Med,  2006.  174.  171-7. 

Disaster Medicine
Lauren Wiesner, MD

  • Blast lung is the most common fatal injury among initial blast survivors
  • Beware of delayed presentation of blast injuries (especially GI), up to 48 hours after the explosion
  • Classic blast lung x-ray shows butterfly pattern
  • Avoid positive pressure ventilation if possible in blast lung. If necessary, use low peep, low tidal volumes (6-8ml/kg), low peak inspiratory pressures less than 35-40 cmH2O, and permissive hypercapnia to pH of 7.25