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RESIDENCY NEWS
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DIDACTIC PEARLS
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Graduating class at Winter Retreat, 2012
Anaphylaxis
Jonathan Davis, MD
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Cutaneous findings can be absent in up to 15% of cases of anaphylaxis
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Consider and document symptom trajectory in your reasoning to give (or not give) epinephrine
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Treatment guidelines recommend intramuscular epinephrine (preferably in lateral thigh) over subcutaneous epinephrine
The diagnosis and management of anaphylaxis practice parameter: 2010 update. J Allergy Clin Immunol 2010;126:3:477.
Cydulka R, Davison D, Grammer L et al. The use of epinephrine in the treatment of older adult asthmatics. Ann Emerg Med 1988; 17:4:322-6.
Evidence Based Anecdotes
Munish Goyal, MD
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Oxygen and IVF are drugs. Only use as much as you need.
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Guide resuscitation with endpoints, usually a combination of gross (mental status), physiologic (HR, MAP) and laboratory (Lactate) markers.
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Consider using BiPAP for 3+ minutes pre-intubation to increase PaO2 for hypoxemic patients who require intubation.
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If you are going to cool a patient post-arrest, initiate ASAP. Also, titrate down the FiO2 to maintain an SpO2 around 96%.
Bickell WH, Wall MJ, et al. Immediate versus delayed fluid resuscitation for hypotensive patients with penatrating torso trauma. NEJM. Vol 331;17. 1994. 1105-9.
Balan IS, Fiskum G, et al. Oximetry-guided reoxygenation improves neurologic outcomes after experimental cardiac arrest. Stroke. 2006, Dec. 37(12). 3008-13.
Che D, Li L, et al. Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest. Critical Care Med, 2011. 39(6). 1423-30.
Kilgannon JH, Jones AE, et al. Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA, 2010. 303(21). 2165-71.
Baillard C, Fosse JP, et al. Noninvasive ventilation improves preoxygenation before intubation of hypoxic patients. American Journal of Respiratory and Critical Care Med, 2006. 174. 171-7.
Disaster Medicine
Lauren Wiesner, MD
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Blast lung is the most common fatal injury among initial blast survivors
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Beware of delayed presentation of blast injuries (especially GI), up to 48 hours after the explosion
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Classic blast lung x-ray shows butterfly pattern
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Avoid positive pressure ventilation if possible in blast lung. If necessary, use low peep, low tidal volumes (6-8ml/kg), low peak inspiratory pressures less than 35-40 cmH2O, and permissive hypercapnia to pH of 7.25
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