Pearls from Dr. Antonis Lectures [July]
Push Dose Pressors:
The following is true regarding the literature on push dose pressors:
A) Unequivocally supports there usage on all hypotensive patients
B) The dosage of Epinephrine for hypotensive patients is 1mg IVP of 1:10,000
C) Phenylephrine has been used on pregnant females undergoing spinal anesthesia
D) Phenylephrine is a pure Beta agonist and increases heart rate dramatically
E) All of the above
REFERENCES:
• Heffner AC et al. Predictors of the complication of postintubation hypotension during emergency airway management. J Crit Care, 2012 Dec;27(6):587-593.
• Thiele RH et al. The clinical implications of isolated alpha (1) adrenergic stimulation. AnesthAnalg. 2011 Aug;113(2):284-296.
• Magder et al. Phenylephrine and tangible bias. AnesthAnalg. 2011 Aug; 113(2): 211-213.
Anticoagulants:
The following is true regarding anticoagulants:
A) New antithrombotics are 100% effective and free of bleeding complications
B) Knowing the generic name of the drug results in 100% accurate medical reconciliation with the patient
C) There are multiple reversal agents with good effectiveness for all the new anticoagulants
D) Some anticoagulants have a narrow therapeutic window and are effected by kidney, bowel, and renal function
E) FFP can completely reverse anticoagulation from Vitamin K antagonists in six hours
REFERENCES:
• Evans G et al. Beriplex P/N reverses severe warfarin-induced overanticoagulation immediately and completely in patients presenting with major bleeding. Br J Haematol. 2001. Dec;115(4):998-1001.
• Connolly SJ et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009. Sep 17;361 (12):1139-51.
• Eerenberg ES et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation. 2011 Oct 4;124(14):1573-1579.
• Patel MR et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011 Sep 8;365(10):883-889.
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Pearls from Dr. Pontius's Chemical Injury Lecture [July]
In general, you can't go wrong with immediate, copious hydrotherapy
Special Circumstances:
--Dry Particles: brush off first
--Phenol: PEG Swab
--Chromic Acid: Topical 5% thiosulfate & ascorbic acid
--Hydrofluoric Acid: Calcium (Subcu or IV) after hydrotherapy
--Oxalic Acid: IV Calcium
--Elemental Oils: Cover with Mineral Oil -- water causes severe exothermic reaction
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Dr. Lane Lecture Pearls [July]
EM Update: Best Practices in Asthma Management
›Determine the severity (clinical pres, vitals, peak expiratory flow rates)
›Avoid testing
›Treat with albuterol, atrovent, oral steroids
›Consider adjuncts in severe asthma exacerbations (Bipap, Magnesium and IV steroids)
›Patiently watch them
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Dr. Ybarra's Vertigo Lecture Pearls [July]
To follow-up regarding my vertigo lecture. Here are some youtube clips:
Head Impulse Test: https://www.youtube.com/watch?v=Wh2ojfgbC3I
Positive skew test: https://www.youtube.com/watch?v=zgqCXef-qPs
Positive DHP followed by examples of nystagmus: https://www.youtube.com/watch?v=cZlXvRlxrRE
I am unaware of specific studies looking at steroids in cerebellar infarct, however in general there is not a role for steroids in the treatment of ischemic stroke.
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Ectopic Pregnancy Lecture Pearls [July]
Dr Omara gave an excellent summary of the issues surrounding 1st trimester bleeding. As supplemental info, attached is the powerpoint that was put together for a joint ob/em conference last winter. The key points are summarized below and were agreed upon by both services. I also have attached the last version of the guideline on ectopic pregnancy - I have reached out to Jeff Dubin for an updated version.
A few key points -
1. A gestational sac is an ultrasound feature of early pregnancy but is NOT diagnostic of an intrauterine pregnancy.
2. It is difficult to distinguish between a true gestational sac and a pseudo-gestational sac, thus if a yolk sac or fetal pole are not visualized, it is considered a "pregnancy of unknown location (PUL)" and needs to be followed with serial bhcg and ultrasounds if patient is stable.
3. Disposition and management are determined by whether a patient is "stable" - vitals, severity of symptoms, physical exam, whether this is a desired vs undesired pregnancy and whether the patient is reliable. Assisted reproductive fertility increases risk.
4. Methotrexate is a medical option that has risk and should only be ordered by gynecology (probably after a discussion with an OB if practicing in a community setting where OB is not in house 24/7). Ibuprofen is contraindicated with methotrexate.
5. Bhcg levels should be correlated with clinical context and ultrasound findings (size of gestational sac). Low bhcg levels may be seen in ectopic pregnancies, missed abortions, and early intrauterine pregnancies. High Bhcg levels above the discriminatory zone (1500 -3500 but we use 2000) with a non-diagnostic ultrasound raise the suspicion for an ectopic pregnancy or missed abortion.
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Dr. Sudarshan LVAD Lecture Pearls [September]
So take home points:
1. Focus on getting good vitals: either a SBP/DBP if they have a pulse, or a MAP by Doppler. Assess the patient by looking for signs of perfusion
2. Most LVAD patients are not in the ED for LVAD issues...assess other problems as usual
3. Call the heart failure team early if you have any issues
4. Echo, EKG, and coags are useful data points to help you figure out what is going on