Reminder: Research Resources 101: “Reliance agreements and external IRBs: A practical guide to collaborative research”
Thursday, 4/18 at noon in SOM 170A. Presenters include Rebecca Rousselle, Hannah Allen & Emory IRB investigators. Register | Read more National Institutes of Health news: “The protocol template for behavioral and social sciences research involving humans is here”
A new Behavioral and Social Sciences Research Template is now available to guide investigators through the systematic development of a comprehensive clinical protocol. Read more
Need help navigating the Department of Medicine Research Administration Service (RAS) Unit? The DOM RAS Unit has issued a one-page document to assist you in working your way through the grant submission process starting with pre-award. Download PDF
Georgia CTSA. The Georgia Clinical and Translational Science Alliance, a collaboration between Emory University, Morehouse School of Medicine, Georgia Institute of Technology and the University of Georgia, offers various programs to support clinical and translational research, including studio consultations for study design and biostatistics, pilot grants, a health services research symposium, clinical research units, a recruitment center and multiple training programs. Read more
Funding & Award Opportunities
Weekly NIH funding opportunities and notices
Federal funding opportunities for public health faculty
Searchable database of internal medicine funding opportunities Rare disease cohorts in heart, lung, blood, and sleep disorders (UG3/UH3 clinical trial not allowed)
Deadline: Friday, 5/17 The purpose of this Funding Opportunity Award (FOA) is to fund research centers that will establish longitudinal cohorts in rare HLBS diseases to investigate unaddressed research questions using epidemiologic study designs and methods that are appropriate for conditions affecting fewer than 200,000 persons in the US. Read more Targeting inflammasomes in substance abuse and HIV (R01 clinical trial not allowed)
Deadline: Friday, 5/24 The scientific objective of this FOA is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Read more Pragmatic clinical trial on efficacy of managing reduced iron stores on risk of clinically important events in older adults with heart failure and anemia (U01 clinical trial required)
Deadline: Wednesday, 6/5 This FOA invites applications for a pragmatic clinical trial to establish efficacy of managing reduced iron stores on risk of clinically important events in older adults with heart failure and anemia. Read more
Novel RNAs in virology (including HIV) and immune regulation: Basic science and therapeutic discovery (R21 clinical trial not allowed)
Deadline: Friday, 6/14 The purpose of this FOA is to support basic science research, from early exploratory studies to therapeutic discovery and development, in novel biologically active viral and/or host RNAs involved in virology (including HIV biology) and immune regulation. Read more Optimizing the management and outcomes for cancer survivors transitioning to follow-up care (R01 clinical trial required)
Deadline: Friday, 6/28 This FOA solicits applications that develop and test models of care for adult survivors of cancer who are transitioning from active treatment to follow-up care. Read more Development of sample sparing assays for monitoring immune responses (U24 clinical trial not allowed)
Deadline: Tuesday, 7/30 The purpose of this FOA is to accelerate the development and validation of sample sparing assays that can be applied for studying the human immune system in health and disease. Read more Targeted prevention for tickborme diseases (R01 clinical trial not allowed)
Deadline: Tuesday, 8/6 The purpose of this FOA is to encourage the development of vaccines and other approaches for the prevention of Lyme disease and/or other tick-borne diseases. Read more Clinical research to improve the oral health of older adults (R01 clinical trial not allowed)
Deadline: Standard dates apply The purpose of this FOA is to stimulate research to address gaps in our knowledge related to the risk factors, access to care barriers, oral health promotion and disease prevention strategies, and clinical management of dental, oral, and craniofacial (DOC) diseases more commonly experienced by older adults. Read more
Laura Hansen (Cardiology) received funding for an American Heart Association Career development award for a project entitled, “Skeletal muscle satellite cells play a role in arteriogenesis and angiogenesis in response to ischemia.” Susan Ray and Jay Steinberg (Infectious Diseases) received funding for a subcontract from the University of Illinois at Chicago for a project entitled, "SUpPress SSI - Single use negative pressure wound therapy (NPWT) to reduce surgical site infections.”
Have you or a colleague recently received an award or grant funding?
Division Research Seminars
Thursday, 4/11 at 7:30 a.m. in the Wesley Woods Health Center, 5th Floor Conference Room
Geriatrics Research Seminar: “The renin-angiotensin system, gut microbiome, and age-related disability: how are they connected?” (Thomas Buford, PhD, The University of Alabama at Birmingham, Nathan Shock Center & Center for Exercise Medicine)
Thursday, 4/11 at 8 a.m. in the Grace Crum Rollins Building, Rita Anne Rollins Room, 8th Floor, SPH
Infectious Diseases Seminar: “Research in progress” (ID Fellows)
Thursday, 4/11 at 8 a.m. in Whitehead, Conference Room 200
Pulmonary Division Research Seminar: “Improving outcomes one breath at a time: The relationship between lung protective ventilation and risk of developing acute respiratory distress syndrome in patients with sepsis” (Casey Cable, MD, MS)
Friday, 4/12 at noon in Emory University Hospital, Hurst Conference Room, E450
Clinical Cardiovascular Research Conference: “Digital approaches to cardiac and vascular rehabilitation: a millennial’s guide” (Arash Harzand, MD, MBA)
Monday, 4/15 at 9 a.m. in Emory University Hospital, Hurst Conference Room, E450
Cardiovascular Biology Seminar: (Ahsan Husain, PhD)
Monday, 4/15 at 5 p.m. in Woodruff Memorial Research Building, Room 317
Endocrine Conference: "Role of the sympathetic nervous system in regulating bone metabolism" (Sundeep Khosla, MD, Mayo Clinic)
Recent Notable Publications
Marina Sorrentino Hernandes (Cardiology)
Domenici RA, Campos ACP, Maciel ST, Berzuino MB, et al. “Parkinson’s disease and pain: Modulation of nocicptive circuitry in a rat model of nigrostriatallesion.” Exp Neurol. 2019 May;315:72-81. Read more
Would you like to highlight a recent notable publication?
Pediatric Research Alliance: “Genetic and cellular mechanisms in human early postnatal brain development.”
Friday, 4/12 at noon in the Whitehead Auditorium Biomedical Research Building.
Eric Morrow, MD, PhD, Mencoff Family Associate Professor of Biology, Brown University, Department of Molecular Biology, Cell biology, and Biochemistry (MCB), Department of Psychiatry and Human Behavior (DPHB) Department of Neuroscience, Director, Developmental Disorders Genetics Research Program (DDGRP), Emma Pendleton Bradley Hospital. Read more
The Emory Center for Clinical and Molecular Nutrition Seminar: “Can environmental pollutants increase child cholesterol levels? An exposome-wide association study”
Thursday, 4/18 at 4 p.m. in the Claudia Nance Rollins Building Room 2001. Vaia Lida Chatzi, MD, PhD, Associate Professor, Keck School of Medicine, University of Southern California will present. Snacks and coffee are provided. Read more (PDF) Health Innovation Commercialization Series - License vs. Startup
Thursday, 4/18 at 11 a.m. at the Parker H. Petit Institute for Bioengineering & Bioscience (IBB) 315 Ferst Drive NW. Learn the pros and cons of different commercialization strategies to help determine the best fit for your technology. Our panel discussion format will allow attendees to ask questions and receive feedback to better understand complex go-to-market strategies. Read more Reminder: 2019 Resident Research Day
Tuesday, 4/30 at noon in EUH Auditorium 2E, Poster session 4-6 p.m. in the Emory School of Medicine Lobby, and 6-8 p.m. at Marlow’s Tavern at Emory Point. This annual event showcases our residents' research achievements and celebrates the collaboration between residents and our dedicated faculty. The event will include a resident focused Grand Rounds with a keynote speech from Alanna Morris, MD and oral presentations from our resident abstract winners. Read more Reminder: Register Now! 6th Annual Health Services Research Day
Wednesday, 5/15 in the School of Medicine Auditorium 110. Join Georgia Clinical & Translational Science Alliance colleagues at this 6th annual health services research symposium and networking opportunity. Oral and poster presentations will be selected from submitted abstracts. Read more
Alicia Lyle, PhD
Division of Cardiology
What is your professional background?
I received my bachelor's degree in applied biology from the Georgia Institute of Technology in 2002. Prior to starting graduate school at Emory University, where I received my PhD in molecular and systems pharmacology in 2009, I worked as a research scientist. After I finished my PhD, I did a post-doctoral fellowship, and I joined the Division of Cardiology at Emory as a faculty member in 2015.
In what division do you work, and who is your mentor?
I am an assistant professor in the Division of Cardiology. I've been incredibly fortunate to have had excellent mentorship from Drs. Kathy Griendling and Bob Taylor. Dr. Bernard Lassegue has also been incredibly helpful and is a wonderful teacher for all things molecular biology.
Briefly describe your research. Why is it important?
My lab is focused on peripheral artery disease (PAD). 1 in 3 people with diabetes develops PAD and these patients are 5 - 10 times more likely to require a major limb amputation. Furthermore, current interventions for this condition are all surgical or invasive. My lab uses molecular, cellular, and in vivo strategies to better understand the neovascularization process and aims to identify potential therapeutic targets to promote neovascularization in PAD patients. We are currently focused on understanding how an inflammatory cytokine called osteopontin promotes the formation of new blood vessels in response to ischemia. More specifically, we have determined that human osteopontin isoforms act as divergent modulators of the neovascularization process, so we are interested in determining how one of the isoforms serves as a negative
inhibitor to the other two isoforms, which promote neovascularization, cell migration and proliferation. What do you like most about Emory?
Emory is an incredibly collaborative and supportive environment with numerous opportunities for service, teaching, and scholarship, which makes it an amazing institution to work.
What is your favorite book, movie, or TV show?
I really love to read, and the books I've enjoyed most recently include The Great Alone and The Nightingale, both by Kristin Hannah, and Where the Crawdads Sing by Delia Owens. What do you like to do in your spare time?
I spend most of my time with my family and friends. My husband and I have two boys (ages 9 and 4 years), and I love watching them figure out what they're really into doing. We also have a golden doddle named Bailey (3 years). Right now, I coach my 9-year old's soccer team, so that's fun! My hobbies include oil painting, running, spinning, and reading.
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