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Latest News from the ISSM - February 7, 2014 Member Login
Study: ED Treatment Should Target Both Physical and Psychosocial Factors

Treatment that addresses both the physical and psychosocial aspects of erectile dysfunction (ED) could be the most effective, American researchers report.

Their study, published online in November in the Journal of Sexual Medicine, examined 40 studies involving ED treatment with phosphodiesterase type 5 (PDE5) inhibitors. 

They focused on psychosocial outcomes of ED treatment because, in their view, past studies have given physical outcomes more emphasis.

They found that men tended to have good relationships and a good quality of life overall.  But men were not satisfied with their sexual relationships.

After PDE5 inhibitor treatment, most men saw improvements, but not in their overall satisfaction with life and relationships. 

The authors pointed out a cyclical relationship between ED and depression. ED often improved when depression symptoms were alleviated. In turn, men felt less depressed when they had better erections.

They wrote, “PDE5 inhibitors are effective in the treatment of ED and, as shown by this review, may be effective in addressing a number of psychosocial factors.”

Please click here for more details on this study. 

New Research Examines Efficacy and Safety of Ospemifene for Dyspareunia

A new research summary has been posted to the ISSM website. 

"The Efficacy and Safety of Ospemifene in Treating Dyspareunia Associated with Postmenopausal Vulvar and Vaginal Atrophy: A Systematic Review and Meta-Analysis" by Yuanshan Cui, MD; Huantao Zong, MD; Huilei Yan, MD; Nan Li, MD; and Yong Zhang, PhD was published online in November in the Journal of Sexual Medicine.

The study is a meta-analysis of six randomized controlled trials involving 1,772 postmenopausal women with vulvar and vaginal atrophy (VVA). The researchers focused on the safety and efficacy of ospemifene in treating dyspareunia in these women.

Please click here to read the summary.

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