In This Issue:

Upcoming Event: NIDDK Chronic Disease Workshop

Recent Event: C4 Center-Wide Seminar

Affiliate Spotlight: Bonny Rockette-Wagner, PhD

C4 Members Awarded 2023 CTSI Grant

Funding Opportunities

Member & Affiliate Publications

Other Recent Publications of Note


Upcoming Event

NIDDK Chronic Disease Workshop

The NIDDK is hosting a workshop titled “Optimizing Clinical Trials In Chronic Disease” on July 24-25, 2023.

This webinar will focus on optimizing clinical trials, focused on improving recruitment, planning, and reviewing available tools from NCATS/CTSA to assist investigators in planning trials.  The agenda includes patient and research coordinator panels, as well as lessons learned from successful clinical trials in the COVID era.

For more information, please email Dr. Kevin Abbott.

Recent Event

C4 Center-Wide Seminar

In February, C4 Affiliate Mylynda Massart, MD, PhD and Kathryn Hartman, MPH from All of Us Pennsylvania presented on the potential ways to use the data from the NIH All of Us Research Program for chronic condition research. 

The NIH is awarding up to $4.75 million in Fiscal Year 2023 for research grants to advance the use of All of Us data, and organizations such as the NHLBI are awarding extra funding through two companion FOAs.

Click here to watch the seminar recording

Affiliate Spotlight: Bonny Rockette-Wagner, PhD

This issue’s C4 Center Affiliate Spotlight features Dr. Bonny Rockette-Wagner. Dr. Rockette-Wagner is an Assistant Professor of Epidemiology at the University of Pittsburgh School of Public Health whose research expertise includes the assessment of the role of physical activity and lifestyle interventions to prevent and treat chronic diseases.

Dr. Rockette-Wagner’s research utilizes pragmatic and community-based clinical trials and epidemiological studies to better integrate referral to physical activity within primary care practice towards improving patient care and long-term health outcomes related to chronic conditions. Dr. Rockette-Wagner is currently working on her K01 project, The Clinical Referral to Physical Activity Study, which is the second of two pilot studies to develop an intervention program aimed at increasing physical activity levels in adult primary care patients with low activity levels and with cardiometabolic risk factors. 

To learn more about Dr. Rockette-Wagner’s work, see her Pitt School of Public Health faculty profile.

C4 Members Awarded 2023 CTSI Grant

In their grant titled Geospatial Analysis of Disparities in Access to and Use of Metabolic Disease Specialty Care, C4 Core Member Margaret Zupa (PI), Affiliate Amber Johnson (Co-I), and Director Ann-Marie Rosland (Co-I) will explore how geographic, transportation, and internet access barriers impact the use of specialty care for adults with type 2 diabetes and cardiovascular disease, and how widespread use of telemedicine since 2020 has impacted disparities in care utilization.

Funding Opportunities

NIH PAS-23-086: Small R01st for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required). Multiple submission deadlines. Next deadlines: 6/5/2023 and 11/5/2023.

NIH PAR-22-092: Health Care Models for Persons with Multiple Chronic Conditions from Populations that Experience Health Disparities: Advancing Health Care towards Health Equity (R01 - Clinical Trials Optional). Multiple submission deadlines. Next deadlines: 6/5/2023 and 2/5/2024.

NIH RFA-OD-23-013: Understanding Chronic Conditions Understudied Among Women (R21 Clinical Trial Optional). Submission deadline 6/20/2023 or 6/20/2024.

NIH RFA-OD-23-014: Understanding Chronic Conditions Understudied Among Women (R01 Clinical Trail Optional). Submission deadline 6/20/2023 or 6/20/2024. 


Member & Affiliate Publications

Seasonal Variation in Blood Pressure Control Across US Health Systems. Nilles EK, Champon X, Mulder H, Shaw KM, Smith M, Lampron ZM, Wozniak G, Chamberlain AM, Carton T, Viera AJ, Ahmad FS, Steinberg BA, Chuang CH, Mctigue KM, McClay JC, Polonsky TS, Maeztu C, Sanders M, Warren N, Singh R, Liu M, VanWormer JJ, Park S, Modrow MF, Rakotz M, Cooper-Dehoff RM, Pletcher MJ, O'Brien EC. J Hypertens. 2023 Mar 6. doi: 10.1097/HJH.0000000000003396. Epub ahead of print. PMID: 36883471.

Insulin Pump-Associated Adverse Events: A Qualitative Descriptive Study of Clinical Consequences and Potential Root Causes. Estock JL, Codario RA, Keddem S, Zupa MF, Rodriguez KL, DiNardo MM. Diabetes Technol Ther. 2023 Mar 3. doi: 10.1089/dia.2022.0498. Epub ahead of print. PMID: 36724310.

Adherence to Diabetes Medications and Health Care Use During the COVID-19 Pandemic Among High-Risk Patients. Yoon J, Chen C, Chao S, Wong E, Rosland AM. J Am Board Fam Med. 2023 Mar 3:jabfm.2022.220319R1. doi: 10.3122/jabfm.2022.220319R1. Epub ahead of print. PMID: 36868867.

Perceived and Calculated Diet Quality Improvements in a Randomized mHealth Weight Loss Trial. Cheng J, Costacou T, Rockette-Wagner B, Sereika SM, Conroy MB, Kriska AM, Kariuki JK, Klem ML, Parmanto B, Burke LE. Behav Med. 2023 Feb 15:1-6. doi: 10.1080/08964289.2023.2178374. Epub ahead of print. PMID: 36789848.

Examining Real-World Therapy Practice of Cognitive Screening and Assessment in Post-Acute Care. Rouch S, Terhorst L, Skidmore ER, Rodakowski J, Gary-Webb TL, Leland NE. J Am Med Dir Assoc. 2023 Feb;24(2):199-205.e2. doi: 10.1016/j.jamda.2022.11.007. PMID: 36525988.


Other Recent Publications of Note

Adjustment for Social Risk Factors in a Measure of Clinician Quality Assessing Acute Admissions for Patients With Multiple Chronic Conditions. Lipska KJ, Altaf FK, Barthel AGB, et al. JAMA Health Forum. 2023 Mar;4(3):e230081. doi:10.1001/jamahealthforum.2023.0081.

How Frequently and for How Long Do Adults With Type 2 Diabetes Use Management Apps? The REALL Study. Fisher L, Fortmann AL, Florissi C, et. al. J Diabetes Sci Technol. 2023 Mar;17(2):345-352. doi: 10.1177/19322968211058766. PMID: 34802281; PMCID: PMC10012363.

Effect of a Telephone Health Coaching Intervention on Hypertension Control in Young Adults: The MyHEART Randomized Clinical Trial. Hoppe KK, Smith M, Birstler J, et al. JAMA Netw Open. 2023 Feb;6(2):e2255618. doi:10.1001/jamanetworkopen.2022.55618.

Early Intervention and Intensive Management of Patients with Diabetes, Cardiorenal, and Metabolic Diseases. Handelsman Y, Butler J, Bakris GL, et. al. J Diabetes Complications. 2023 Feb;37(2):108389. doi: 10.1016/j.jdiacomp.2022.108389. PMID: 36669322.

Adherence to a Healthy Lifestyle in Association With Microvascular Complications Among Adults With Type 2 Diabetes. Liu G, Li Y, Pan A, et al. JAMA Netw Open. 2023 Jan;6(1):e2252239. doi:10.1001/jamanetworkopen.2022.52239.


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