Research Team Studies Long-Term Effects of Different Testosterone Formulations
ESSM Congress Planned for February 2016 in Madrid, Examinations Offered
Men taking testosterone usually use one of three methods - gels applied to the skin, injections into a muscle, or pellets implanted under the skin. While all of these methods are effective, data on the long-term effects of these formulations have been lacking.
Researchers from Baylor College of Medicine conducted a three-year study of 178 men on these three formulations to compare the effects on testosterone levels, estradiol, hemoglobin, hematocrit, prostate-specific antigen (PSA), total cholesterol, triglycerides, LDL cholesterol, and HDL cholesterol.
Men receiving injections had the biggest increases in testosterone. They also had the highest rates of erythrocytosis based on hemoglobin and hematocrit measurements. Those using gels and those receiving injections had the most significant increases in estradiol. None of the men had significant PSA or cholesterol increases.
The study was published recently in Sexual Medicine, the ISSM's open access journal. Please click here for more details.