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Issue 1: FY2019 Q2 (October 1, 2018 – January 31, 2019)
Letter from the Director
Welcome to the first edition of the PM&R Research Newsletter! This new, quarterly update from the Research Program will assist in keeping all members of the Department up to date on PM&R research studies, faculty and trainee research accomplishments, important deadlines and information, and exciting events you don’t want to miss. Our goal is to increase transparency, improve communication and provide better access to research resources. Our department hosts diverse research interests, and our faculty, residents, fellows and staff conduct research at multiple locations, including Froedtert Hospital, the Clement J. Zablocki VA Medical Center, and Children’s Hospital, in addition to collaborating with partners at UW-Milwaukee, UW-Madison, Marquette University and beyond!
Our Research Program has made some significant advances over the last year, including the addition of the Research Intensive Track to our Residency Program. Developing this track was a collaborative effort between the Education and Research Programs. The Research Intensive Track provides an advanced research experience for residents and includes advanced mentorship, protected time, non-competitive funding, and greater expectations for productivity. We have welcomed three residents (Erin Beddows, Michael Harper, Nick Donahue) onto the Research Intensive Track and look forward to continuing to grow our resident research experience.
The Research Program also offers funding opportunities through the Research Administration Committee (RAC). The RAC funds pilot projects up to $5,000 for PM&R faculty members through our Pilot Award Program. The intent of this award is to provide funding to generate necessary preliminary data that will lead to extramural funding or significant improvements to clinical care. The RAC also funds travel to national meetings to present original research through the RAC Travel Award. Although applications for both awards are currently paper-based, we will be taking the application process online beginning July, 2019. Please contact Moriah Iverson, MS, Program Manager, at miverson@mcw.edu for more information.
We are excited about the opportunity to share information about our Research Program with the Department. Please let us know if you have questions, comments, feedback or suggestions for items to include in future quarterly updates.
Sincerely,
Matt Durand, PhD
Research Director
Assistant Professor
Moriah Iverson, MS
Program Manager, Research and Community Engagement
Meet the Team
The PM&R Research Team is comprised of Matt Durand, PhD, Research Director, Moriah Iverson, MS, Program Manager II, and Rachel Minkin, MS, Clinical Research Coordinator II. Jennifer Nguyen is the Research Assistant for the Durand Lab. Together, we serve all PM&R faculty, fellows, residents and staff at Froedtert Hospital & Medical College of Wisconsin, the Clement J. Zablocki VA Medical Center, and Children’s Hospital. We also serve the Stroke Rehabilitation Center of Southeastern Wisconsin, a collaborative initiative between Marquette University’s Departments of Biomedical Engineering and Physical Therapy and the Medical College of Wisconsin Department of Physical Medicine and Rehabilitation.
The best way to contact the research team is through email. We make every effort to respond within 1 business day. Below is a list of common research issues and who to contact. When in doubt, please send an email to Matt Durand and cc Moriah Iverson and Rachel Minkin.
Questions about the IRB (FH/MCW, VA CH), OCRICC or other research regulations, Research Administration Committee applications, or accessing the Stroke Survivor Recruitment Database: Rachel Minkin, MS
Questions about research project budgets, an invoice, subaward, account, grant applications, or community engagement: Moriah Iverson, MS
Questions about writing a manuscript or abstract, how to establish/manage a research collaboration, or project development: Matt Durand, PhD
Submission of travel reimbursement materials for the PGY2 Research Education Fund or RAC Travel Award: Jennifer Nguyen, BS
Back row (left to right): Moriah Iverson, MS, Program Manager; Matt Durand, PhD, Research Director. Front row (left to right): Jennifer Nguyen, BS, Research Assistant; Rachel Minkin, MS, Clinical Research Coordinator
Currently Approved Studies
The Department of PM&R currently has 32 IRB approved studies with a PM&R faculty Principal Investigator. The Research Program provides assistance on opening, monitoring and reporting, and closing IRB protocols at Froedtert Hospital & Medical College of Wisconsin, the VA and Children’s Hospital. If you are interested in opening a new research study or have any questions related to the IRB please contact Rachel Minkin, Clinical Research Coordinator II at rminkin@mcw.edu.
Scholarly Activity in PM&R
Faculty in PM&R published three peer-review manuscripts and three book chapters this quarter. Our Department was represented in three posters presented at the AAPM&R National Assembly in October, two posters presented at the AAP National Meeting in February in February, and one oral presentation at the International Stroke Conference in February. Our faculty had one grant funded, submitted three grants as Principal Investigators, and submitted four grants as Co-Investigators in collaboration with the Department of Neurology, the Department of Pediatrics at Children’s Hospital of Wisconsin, the University of Wisconsin-Milwaukee, and Marquette University. Congratulations and good luck to our applicants!
Please reach out to Moriah Iverson, MS at miverson@mcw.edu if you have any questions regarding grant applications. The Research Program is always available to proofread or assist with development of your manuscripts, posters, grants and any other research related materials.
Peer-Review Articles
Connelly, P., List C. The effect of understanding issues of personal finance on the well-being of physicians in training. Wisconsin Medical Society 117:4. October 2018
Murphy, SA; Negro, F; Farina, D; Onushko, T; Durand, MJ; Hunter, SK; Schmit, BD; Hyngstrom, AS. Stroke Increases Ischemia- related decreases in Motor Unit Discharge Rates. J Neurophysiol. 2018 Dec 1;120(6):3246-3256. doi: 10.1152/jn.00923.2017. Epub 2018 Oct 31.
Durand, MJ; Ait-Aissa, K; Levchenko, V; Staruschenko, A; Gutterman, DD; Beyer, AM. Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries. Cardiovasc Res. 2018 Nov 22
Durand, MJ; Boerger, T; Nguyen, J; Alqahtani, S; Wright, M; Schmit; B; Gutterman; DD; Hyngstrom; A. Two Weeks of Ischemic Conditioning Improves Walking Speed and Reduces Neuromuscular Fatigability in Chronic Stroke Survivors. Appl Physiol (1985). 2019 Jan 17
Book Chapters
Del Toro, D; Seslija D; King J. (2019) Fibular Neuropathy. Frontera, Silver, Rizzo. Essentials of Physical Medicine and Rehabilitation (Chapter 75). Philadelphia, PA Elsevier
Del Toro D; Seslija D. (2019) Tibial Neuropathy. Frontera, Silver, Rizzo. Essentials of Physical Medicine and Rehabilitation (Chapter 94). Philadelphia, PA Elsevier
Braza, DW; Yacub Martin, J. (2019) Diabetic Food and Peripheral Artery Disease. Frontera, Silver, Rizzo. Essentials of Physical Medicine and Rehabilitation (Chapter 129, pp. 719-723). Philadelphia, PA Elsevier
Posters and Oral Presentations
Miller, C., Garlanger, K., Kortes, S., Riebe, J., Schnorenberg, A., Slavens,B., Lee, K. (2018, October). Biomechanical Analysis of Wheelchair Athletes with Paraplegia during Cross-training Exercises. Poster session presented at the American Academy of Physical Medicine and Rehabilitation Annual Assembly, Orlando, FL.
Beddows, E., Orr, M. (2018, October). A Case Report: Ascending Paresis: An Atypical presentation of Bannwarth Syndrome. Poster session presented at the American Academy of Physical Medicine and Rehabilitation Annual Assembly, Orlando, FL.
Cyr, A., Nelson, A. (2018, October). Thoracic Back Pain and Spinal Cord Compression as Initial Presentation as Diffuse Large B-Cell Lymphoma: A Case Report. Poster session presented at the American Academy of Physical Medicine and Rehabilitation Annual Assembly, Orlando, FL.
Jozwiak, M., Wu, H. (2019, February). Management of Complex Regional Pain Syndrome with Spinal Cord Stimulator During Pregnancy: A Case Report. Poster session presented at the Association of Academic Physiatrists Annual Meeting, San Juan, Puerto Rico.
Pfeiffer, J., White, C. (2019, February). Conservative, pain management of pre-sacral schwannoma. Poster session presented at the Association of Academic Physiatrists Annual Meeting, San Juan, Puerto Rico.
Durand, M., Nguyen, J., Wright, M., Gutterman, D., Schmit B., Hyngstrom S. (2019, February). Ischemic Conditioning Improves Brachial Artery Flow Mediated Dilation in Chronic Stroke Survivors. Oral presentation at the International Stroke Conference, Honolulu, Hawaii.
Grants Awarded
Title: Ischemic Conditioning Improves Walking Function Post Stroke
Principal Investigator: Allison Hyngstrom, PT, PhD, Marquette University
Co-Investigator: Matt Durand, PhD
Sponsor: American Heart Association Institutional Research Enhancement Award (AIREA)
Total Award: $154,000
Award Dates: 01/01/2019 – 12/31/2020
Grants Submitted
(all submissions are pending sponsor decision)
Title: Ischemic Conditioning and Improved Motor Function Post Stroke
Principal Investigators: Matt Durand, PhD, Allison Hyngstrom, PT, PhD, Marquette University
Sponsor: NIH Child Health and Human Development - R01
Total award: $2,250,071
Title: Botulinum Toxin A for the Treatment of Chemotherapy-induced Peripheral Neuropathy
Principal Investigator: Erin McGonigle, MD, and Erin Beddows, MD
Sponsor: Merz Pharmaceuticals
Total award: In-kind product donation
Title: Determining the usefulness of soft continuum robot for stroke rehabilitation
Principal Investigator: Jinsung Wang, PhD
Co-Investigator: Brian Robertson-Dick, MD
Sponsor: University of Wisconsin-Milwaukee: Research Growth Initiative
Total award: $3,700
Title: Upper Extremity Spasticity Quantification Using Muscle Resistance Force and EMG Signals
Principal Investigator: Jinsung Wang, PhD
Co-Investigator: Brian Robertson-Dick, MD
Sponsor: University of Wisconsin-Milwaukee: Research Growth Initiative
Total award: $8,506
Title: A novel bilateral training approach in upper extremity stroke rehabilitation utilizing wearable soft robotic technology
Principal Investigator: Jinsung Wang, PhD
Co-Investigator: Brian Robertson-Dick, MD
Sponsor: University of Wisconsin-Milwaukee, NIH Neurological Disorders and Stroke - R03
Total award: $14,206
Title: Using art to increase health literacy of physical activity in patients with Parkinson Disease
Principal Investigators: Ryan Brennan, MS, Neurology and Erin McGonigle, MD
Sponsor: Parkinson’s Foundation
Total award: $25,000
Title: Quantification of Shoulder Pathology and Manual Wheelchair Propulsion in Children and Adults with Spinal Cord Injury using Advanced Biomechanical Modeling and Diagnostic Imaging
Principal Investigator: Brooke Slavens, PhD, UW-Milwaukee
Co-Investigator: Mark England, MD
Significant Contributors: Ken Lee, MD, Vaishnavi Muqeet, MD
Sponsor: University of Wisconsin – Milwaukee, NIH National Institute of Child Health Development - R01
Total award: $1,250,000
Research Administration Committee
The Research Administration Committee (RAC) is comprised of PM&R faculty, residents and staff. The purpose of the RAC is to guide research and research administration in the department to facilitate high-quality, novel research that will significantly contribute to our field and to identify strategic ways to use PM&R resources to leverage research growth. The RAC monitors the status of IRB-approved studies, Quality Improvement Reviews conducted by MCW’s Human Research Protection Program, PM&R research events such as Research Grand Rounds and Research Day and offers opportunities for research funding through the PGY2 Research Education Fund, the RAC Pilot Award and the RAC Travel Award. Interested in joining the RAC? Please contact Moriah Iverson for more information on membership!
The RAC Pilot Award budget for FY2019 was $20,000. We have $18,500 in Pilot Award funds remaining through June 30, 2019 and encourage PM&R faculty to apply. Please contact Rachel Minkin for information on the application process. The RAC Pilot Award application process will be moved online beginning July 1, 2019!
The RAC Travel Award budget for FY2019 is $10,000. We have $2,500 remaining through June 30, 2019. Please contact Rachel Minkin for the application form. The RAC Travel Award will also be available online as on July 1, 2019. Travel reimbursement materials can be submitted to Jennifer Nguyen. As a reminder, RAC Travel Award recipients are required to submit their work as a manuscript prior to applying for another RAC Travel Award. We strongly encourage all RAC Travel Award Recipients to submit their work and are happy to assist in that process. Please contact Matt Durand for questions regarding publication.
The PGY2 Research Education Fund has provided the opportunity to send all six PGY2 residents to national conferences this year. Residents will present on their experience at Research Grand Rounds. Many thanks to the John Melvin Endowment for providing this wonderful opportunity for our trainees! Our department is one of the only PM&R residency programs to provide this experience. If you are interested in contributing funds for this important program, please contact Moriah Iverson.
Research Day 2019
Research Day will be held May 16 from noon to 5 p.m. in the Hub for Collaborative Medicine at MCW (Room A1015). Research Day is a time to celebrate the research accomplishments of our graduating trainees as they present on their resident and fellowship research projects. Our trainees are dedicated to advancing cutting-edge patient care through research. Please join us in congratulating them on all of their accomplishments!
We are thrilled to share that Sara Cuccurullo, MD, will be this year’s Research Day keynote speaker. Dr. Cuccurullo is a leader in the field of PM&R, serving as Clinical Professor and Chairman, and Residency Program Director at Rutgers-Robert Wood Johnson Medical School/JFK Medical Center, and is the Medical Director and Vice President of the JFK Johnson Rehabilitation Institute. She is dedicated to resident education and has taught the Board Review Course for PM&R residents since 1991. Dr. Cuccurullo serves as the Editor in Chief of the Physical Medicine and Rehabilitation Board Review textbook (Demos Publishing) and is the Vice President of the National Residency and Fellowship Program Directors Council for the AAP. She also serves as an invited editor for The American Journal Of PM&R.
Dr. Cuccurullo has multiple publications on a competency model she pioneered and has presented this model nationally at the AAP and the AAPM&R meetings. She cares for patients on the JFK Medical Center Consult Service, where she has collaborated on developing the Total Joint Protocols and Stroke Protocols used in the acute care hospital. We are excited that such a dedicated faculty will be with us to celebrate our graduating trainees! Please contact Rachel Minkin at rminkin@mcw.edu with any questions.
Upcoming Research Events
March 2019
March 21: MCW Libraries Orientation, 3:30–4 p.m., HUB A3540, registration recommended
March 22: Research Administration Committee Meeting, 1–2 p.m.
April 2019
April 8: Citation Mangers Drop-in Training 10–11 a.m., Medical Education Building M3250
*in-depth citation manager training can be obtained by completing the Reference Consultation Service form! This training includes EndNote, which PM&R has a license for. Contact MCW IS to get EndNote installed on your computer.
April 19: Research Grand Rounds, noon–1 p.m.
April 25: MCW Libraries Orientation, 3:30–4 p.m., HUB A3540, registration recommended
April 26: Research Administration Committee Meeting, 1–2 p.m.
May 2019
May 13: Citation Mangers Drop-in Training, 10–11 a.m., Medical Education Building M3250
*in-depth citation manager training can be obtained by completing the Reference Consultation Service form! This training includes EndNote, which PM&R has a license for. Contact MCW IS to get EndNote installed on your computer.
May 16: Research Day with guest speaker Sara Cuccurullo, MD, noon–5 p.m., HUB 1015
May 17: Research Grand Rounds, noon–1 p.m., Moriah Iverson, MS
May 23: Searching for Grant Funding 2–2 p.m., HRC Todd Wehr Library, Lois Martin Memorial Conference Room, 3rd floor
May 24: Research Administration Committee Meeting, 1–2 p.m.
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