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EDITOR'S NOTE: Big4Bio newsletters will not be published from Sept 4th-7th; they will resume distribution on Tuesday, Sept 8th.

September 3, 2026
Regional intelligence on Drugs, Diagnostics, Devices & Digital Health
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Big4Bio CEO Weekly - Q&A Life Sciences Leaders
BIG4BIO CEO WEEKLY Q&A:
James Mackay, Ph.D., President & CEO, Crystalys Therapeutics
In this Q&A, Mackay discusses the clinical setback that led him to found Crystalys, what sets dotinurad apart from earlier gout therapies, the company's recent milestones, and where he sees the company heading over the next three years. More

Press Releases

One Partner For Your Entire Vivarium. Research Ready From Day One.
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  • Revolution Medicines: New England Journal of Medicine Publishes Phase 1/2 Clinical Data on RASONQUE (daraxonrasib) in Metastatic Non-Small Cell Lung Cancer More More*
  • Ultragenyx: Phase 3 Aspire Results in Angelman Syndrome More More More* More*

Financial News

Investment Banking Advisory to the Life Science Industry
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  • LSN: Hot Investor Mandates (Updated 09/01) More
  • Olema Oncology: Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) More
  • Scribe Therapeutics: Second Quarter 2026 Financial Results and Recent Corporate Highlights More

Media/Misc Coverage

  • Big4Bio CEO Weekly Q&A: James Mackay, Ph.D., President & CEO, Crystalys Therapeutics More
  • Biotech & Pharma Updates | September 2, 2026 More
  • More on Ultragenyx FDA-Approved Treatment Showing Sustained Reduction in Cornstarch Intake More
  • Subscribe to LifeSci Startup for Updates on US Startups More

Career Moves

Telling Your Science Story to Investors
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  • Cellares Details Layoffs as Fast-Growing Bay Area Company Reacts to Loss of Major Customer More* More
  • Eikon Therapeutics: Appoints Ching-Pin Chang, M.D., Ph.D. as Executive Vice President and Chief Scientific Officer More
  • More on ArsenalBio Laying Off 99 Employees and Shifts Focus to In Vivo CAR-T Programs More More*
  • OPPORTUNITY: Head of Global Research & Development, Columbia, MD More
  • OPPORTUNITY: Head of Marketing & Communications, Remote More
  • OPPORTUNITY: Vice President, Business Development, Remote More
  • Slone Partners: Fractional Leadership in Biotech and Life Sciences: When it Works and Why More
  • Slone Partners: ICYMI - How to Keep Your Highest Performers Engaged More

Events

Note: Events may be in any Big4Bio region or virtual
Spotlight Event: BioFuture Oct 27-28
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SEE FULL EVENT SCHEDULE AT THE BIOCALENDAR

Companies

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