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EDITOR'S NOTE: EDITOR'S NOTE: Big4Bio newsletters will not be published on Nov 11th; they will resume distribution on Wednesday, Nov 12th.

NoVEMber 7, 2025
Covering Life Sciences Drugs, Diagnostics, Devices, Digital Health
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Press Releases

  • Akero Therapeutics: Presents New Analyses From Phase 2b SYMMETRY and HARMONY Trials of Efruxifermin at 76th Annual AASLD The Liver Meeting 2025 More
  • A2 Biotherapeutics: Presents Initial Safety and Efficacy Data From Ongoing Phase 1/2 EVEREST-2 Study, Including First Report of a Complete Response to CAR T-Cell Therapy in a Patient With NSCLC More
  • Aulos Bioscience: New Phase 2 Data for Imneskibart Reveal Clinical Activity in Melanoma and Non-Small Cell Lung Cancer More
  • Coherus Oncology: Arvind Sood Joins As Chief Strategy and Corporate Affairs Officer More
  • Denali Therapeutics: Board and Executive Leadership Updates More More* More*
  • Gilead: Livdelzi Demonstrates Sustained Efficacy in Primary Biliary Cholangitis (PBC), Offering Alkaline Phosphatase (ALP) Reduction, Itch Relief and Potential to Slow Disease Progression More
  • Gilead: Update on Phase 3 ASCENT-07 Study More
  • Nurix Therapeutics: Presents New Translational Data from First-in-Human Clinical Trial of Oral CBL-B Inhibitor NX-1607 Demonstrating Immune Activation and Tumor Microenvironment Remodeling More
  • ORIC Pharmaceuticals: Publication in Cancer Research on the Discovery and Development of Enozertinib, a Highly Selective, Brain-Penetrant EGFR Inhibitor More
  • Synthekine: Presents Positive Initial Results from Phase 1a/1b Clinical Trial of STK-012 Plus Pembrolizumab and Chemotherapy in First-Line, PD-L1 Negative Nonsquamous Non-Small Cell Lung Cancer More
  • Tahoe Therapeutics: Welcomes Proven Discovery Leaders Wayne Spevak, Ph.D., and Ben Powell, Ph.D., to Advance Drug Discovery More
  • UroViu: Receives CE Certification of Its Wi-Fi Enabled Cystoscope and Hysteroscope Product Portfolio More
  • Vera Therapeutics: Positive ORIGIN Phase 3 Data for Atacicept in IgA Nephropathy Presented at ASN Kidney Week 2025 and Published in the New England Journal of Medicine More
  • 8 More*

Financial News

Investment Banking Advisory to the Life Science Industry
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  • Aligos Therapeutics: Recent Business Progress and Third Quarter 2025 Financial Results More
  • Allogene Therapeutics: Third Quarter 2025 Financial Results and Business Update More
  • Cerus: Record Results for Third Quarter 2025 and Raises Full Year 2025 Product Revenue Guidance More
  • Codexis: Third Quarter 2025 Financial Results More
  • Coherus Oncology: Third Quarter 2025 Financial Results and Provides Business Update More
  • CytomX Therapeutics: Third Quarter 2025 Financial Results and Provides Business Update More
  • Denali Therapeutics: Third Quarter 2025 Financial Results and Business Highlights More
  • Exclusive VC Funding Data from BYTE51, with Special Big4Bio Pricing More
  • Guardant Health: Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) More
  • JPM Week Conference Readiness Packages (Big4Bio Subscriber Discount) More
  • LSN: Hot Investor Mandates (Updated 11/04) More
  • Maze Therapeutics: Third Quarter 2025 Financial Results and Recent Highlights More
  • More on BillionToOne IPO Becoming $5 Billion Explosion As Bay Area Medical Test Maker’s Stock Soars in Debut More*
  • More on Braveheart Bio Bagging $185M for Drug That Could Rival a Bristol Myers Squibb Cardio Med More*
  • Nurix Targets $250 Million Stock Sale to Back Pivotal Study of Leukemia Drug More*
  • Pliant Therapeutics: Corporate Update and Reports Third Quarter 2025 Financial Results More
  • Rani Therapeutics: Third Quarter 2025 Financial Results; Provides Corporate Update More
  • Rezolute: First Quarter Fiscal 2026 Financial Results and Provides Business Update More
  • Seer: Third Quarter 2025 Financial Results More
  • Spotlight: Essential Financial Moves to Help You Survive the Biotech Winter More
  • Structure Therapeutics: Third Quarter 2025 Financial Results and Recent Highlights More
  • ‘We Jumped All Over It’: How Drug Maker Evommune Took Advantage of the Federal Shutdown To Nail a $150 Million IPO More* More*
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Media/Misc Coverage

San Francisco's most flexible contract vivarium lab space: Start with a few cages and grow.
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  • BioPharmGuy News: Weight Lost, AI Letters, Post Doctor, Correlation Lawsuit, Mr. Peanut Butter More 
  • Subscribe to LifeSci Startup for Updates on US Startups More
  • The Big4Bio Podcast: Every Moment Matters: Navigating the Complexities of Drug Discovery Podcast

Companies

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Career Center

Premier Executive Search and Talent Advisory Firm Slone Partners Launches Fractional Talent Service to Deliver On-Demand Leaders and Specialists
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  • Feature: The Rise of Fractional Talent in Life Sciences: What to Expect in 2026 More
  • ICYMI: CEO’s Perspective: Big Moves Come with Big Responsibility More
  • ICYMI: CEO’s Perspective: The High Cost of Job Hopping More
  • ICYMI: Elevating Executive Presence: A Blueprint for Life Sciences and Biotech Leaders More
  • ICYMI: The Power of Peer Learning - Why Even Top Biotech Leaders Need Mentorship More
  • ICYMI: What’s Next in Precision Medicine: Leadership Challenges and Opportunities More
  • OrbiMed-Backed Biotech Quickly Changes CEOs; Adaptimmune Co-Founder to Lead Evaxion More*
  • SJU: Path to Commercialization - Jennifer Rafferty (Field Reimbursement Manager) From Regeneron Podcast
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