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EDITOR'S NOTE: Big4Bio newsletters will not be published from Dec 16, 2025, to Jan 4, 2026; they will resume distribution on Monday, Jan 5, 2026.

DEcember 15, 2025
Covering Life Sciences Drugs, Diagnostics, Devices, Digital Health
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Press Releases

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  • Abpro: Submission of an IND Application to Initiate a Phase 1 Clinical Trial of T Cell Engager ABP-102/CT-P72 for HER2-positive Cancers More
  • Aviceda Therapeutics: Phase 2b SIGLEC Results for AVD-104 in Geographic Atrophy More
  • Fondazione Telethon and Orphan Therapeutics Accelerator: Sign Memorandum of Understanding to Pioneer Non-Profit Commercial Access Model for Ultra-Rare Disease Gene Therapy in the US More
  • Innoviva Specialty Therapeutics: U.S. FDA Approves NUZOLVENCE (zoliflodacin), a First-in-Class, Single-dose, Oral Antibiotic for the Treatment of Uncomplicated Urogenital Gonorrhea in Adults and Adolescents More
  • Insulet: Expands Omnipod U.S. Recycling Program, Diverting Millions of Pods From Landfills and Creating a More Sustainable Future More
  • Manifold Bio: Expands Leadership Team to Drive Its AI + In Vivo Targeted Biologics Platform More
  • Moderna: EMA Committee for Medicinal Products for Human Use Adopts Positive Opinion Recommending Authorization of mNEXSPIKE (COVID-19 Vaccine, mRNA) More
  • Thermo Fisher Scientific: Expands Gibco Bacto Portfolio With Next-Generation, Chemically Defined Media to Boost E. coli Biomanufacturing Productivity More
  • Zenas BioPharma: Partner, InnoCare Pharma, Announces Achievement of Primary Endpoint in Phase 2b Study of Orelabrutinib, a BTK Inhibitor, for Systemic Lupus Erythematosus More
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Financial News

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  • Attivare Therapeutics: Awarded $6.6 Million Grant to Advance Durable Malaria Vaccine More
  • Cambridge Biotech Receives $255M in Sale of Spinout to BMS More*
  • CAMP4 Therapeutics: Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) More
  • Enveric Biosciences: Closing of Exercise of Warrants for $3.1 Million Gross Proceeds More
  • Get Full Access to BYTE51 Life Sciences Intelligence for 50% Off  More
  • JPM Week Conference Readiness Packages (Big4Bio Subscriber Discount) More
  • NANOBIOTIX: Will Join CAC Mid 60 and SBF 120 Indices on Euronext Paris More
  • Navigating Post-IPO Financial Reporting More
  • Scholar Rock: New Employee Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) More
  • Vicarious Surgical: Full Year 2026 Cash Burn Guidance More
  • Vor Bio: $150 Million Private Placement More

Media/Misc Coverage

Pace® Life Sciences

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  • BiotechTV: CREATE Medicines’ Platform Allows It to Program CARs Into Multiple Immune Cell Types Inside the Body, and is Redosable. While This Includes CAR-T, They Believe That "In Vivo Is More Than T-Cells." Video
  • Boston's Lab Developers Are Falling Out Of Love With Spec Suites More*
  • Subscribe to LifeSci Startup for Updates on US Startups More
  • The Big4Bio Podcast: Every Moment Matters: Integrating AI into Drug Discovery Podcast

Companies

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Career Center

Premier Executive Search and Talent Advisory Firm Slone Partners Launches Fractional Talent Service to Deliver On-Demand Leaders and Specialists
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  • M&A in Life Sciences: The Turning Tide – Why Now is a Strategic Inflection for Biopharma and Biotech More
  • ICYMI: CEO’s Perspective: Big Moves Come with Big Responsibility More
  • ICYMI: CEO’s Perspective: The High Cost of Job Hopping More
  • ICYMI: Elevating Executive Presence: A Blueprint for Life Sciences and Biotech Leaders More
  • ICYMI: The Power of Peer Learning - Why Even Top Biotech Leaders Need Mentorship More
  • ICYMI: What’s Next in Precision Medicine: Leadership Challenges and Opportunities More
  • The Rise of Fractional Talent in Life Sciences: What to Expect in 2026 More

Event Center

Note: Events may be in any Big4Bio region or virtual
Biotech Showcase, Jan 12-14
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  • Know Before You Go: AI in 2026 — Signals, Risks, and Real-World Impact (Pre-JPM Event) Jan 6
  • BLPN Investor Summit Jan 8-10

SEE FULL EVENT SCHEDULE AT THE BIOCALENDAR

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