VIEW IN BROWSER

EDITOR'S NOTE: Big4Bio newsletters will not be published Nov 26th-28th; they will resume distribution on Monday, Dec 1st.

november 25, 2025
Covering Life Sciences Drugs, Diagnostics, Devices, Digital Health
* may need subscription to view
Enter JPM26 prepared for any conversation with a defensible commercialization plan that captures your asset's value and journey. CORVAL COMPASS | See a sample >>

Press Releases

Boston's most flexible contract vivarium lab space: Start with a few study cages and grow.
Learn More  →
  • Biogen: Eisai Completes Rolling Submission to US FDA for LEQEMBI IQLIK (lecanemab-irmb) Supplemental Biologics License Application as a Subcutaneous Starting Dose for the Treatment of Early Alzheimer’s Disease Under Fast Track Status More
  • HKeyBio: Launches the HKEY-AIDMD 3.0--a Next-Generation Platform to Crack the Toughest Challenge in Autoimmune and Allergy Drug Development - Multi-target Combination Strategy Optimization More
  • Kelonia Therapeutics: Late-Breaking Oral Presentation of First-in-Human Data From in vivo BCMA CAR-T Therapy at the American Society of Hematology (ASH) 2025 Annual Meeting More
  • Kymera Therapeutics: First Patient Dosed in BROADEN2 Phase 2b Atopic Dermatitis Clinical Trial of KT-621, a First-in-Class, Oral STAT6 Degrader More
  • NeuroSense: Receives FDA Clearance to Initiate Pivotal Phase 3 Trial for PrimeC in ALS More
  • 1910: Publishes CANDID-CNS, an AI Model That Unlocks Beyond Rule of 5 Chemical Space and Stereochemistry to Predict Blood–Brain Barrier Penetration More
  • Vertero: Initiates Phase 1 Study of VT-5006, a Selective Small Molecule Therapy for Parkinson’s Disease More
  • Vyome: Appoints Renowned Medical Oncologist, Dr. Aditya Bardia, as Senior Medical Advisor to Guide the Development of MFW Program More
A single platform for private Biotech & VC intelligence. Reliable. Real-time. Affordable. BYTE51 - Exclusive pricing for Big4Bio Readers

Financial News

The Charles River CFO Advantage
Reassessing your business plan?
We provide financial leadership.
Smart. Nimble. Flexible.
Learn More  →

  • BYTE51: Exclusive Pricing on Private Biotech & VC Intelligence More
  • Climb Bio: Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) More
  • CureVac: Financial Results for the Third Quarter and First Nine Months of 2025 and Provides Business Updates More
  • Dana-Farber Cancer Institute: Awarded $20 Million Grant From the Elaine and Eduardo Saverin Foundation More More*
  • Enquyst Technologies: Demonstrates First-in-Class, Chromatography-free Downstream Processing of a Monoclonal Antibody (mAb) With Its Patented Isoelectric Point Purification (IPP) Technology Platform and Announces Receipt of a National Institute for Innovation in Manufacturing Biopharmaceutical (NIIMBL) Led Gates Grand Challenge Program Award More
  • IQHQ Halts Development on $1B Fenway Center Life Sciences Project More*
  • JPM Week Conference Readiness Packages (Big4Bio Subscriber Discount) More
  • MindImmune: Extends Series A to $30M to Advance Inflammation-Focused Alzheimer’s Therapy Into the Clinic and Appoints Isaac Stoner as CEO More
  • More on Versant’s Dayra Dawning With $50M Biogen Pact, Oral Macrocyclic Peptide Mission More More More
  • Nanobiotix: Third Quarter 2025 Operational and Financial Update Along With 2026 Clinical Outlook More
  • Nuvalent: Closing of Public Offering of Common Stock and Full Exercise by Underwriters of Option to Purchase Additional Shares From Selling Stockholders More
  • ProMIS Neurosciences: Reverse Stock Split More
  • The One Big Beautiful Bill Act: A Guide to Small Business Taxes More
  • Thermo Fisher Scientific: Prices Offering of Euro-Denominated Senior Notes More
Need financial expertise? Flexible. Fractional. Finance. CRCFO >>

Media/Misc Coverage


  • Broad: New AI Model Could Speed Rare Disease Diagnosis More
  • ICYMI: Boston Life Sciences Times Announces 2025 Vanguard Award Winners More
  • Moderna Exec Explains Shift to Onshore Manufacturing, Norwood Investment More*
  • More on Sarepta Sharing Positive Safety Update on DM1 Asset as Arrowhead Snares $200M Milestone More
  • Subscribe to LifeSci Startup for Updates on US Startups More
  • The Big4Bio Podcast: Every Moment Matters: How NAMs Are Rewriting the Rules of Antibody Discovery Podcast
Cyprotex - An Evotec Company | Your trusted ADME-Tox partner. Cyprotex offers validated NAMs ready to deliver human-relevant insights from day one! Learn more >>

Companies

DISCOVER COMPANIES
Big4Bio: Boston Life Science Company Directory
Locate a specific company or explore new companies in life science.
Explore our Company Directory
Provided courtesy of
BioPharmGuy Logo
Feature your company
Apply to have your company showcased by Big4Bio
Apply Today
Wacker Biotech - We are your partner. Flexible, reliable delivery of your: pDNA - mRNA - LNP | Proteins | Live Microbials | Vaccines. Partner with a global  CDMO backed by a science-driven powerhouse. Better with WACKER >>

Career Center

Premier Executive Search and Talent Advisory Firm Slone Partners Launches Fractional Talent Service to Deliver On-Demand Leaders and Specialists
Learn More  →
  • M&A in Life Sciences: The Turning Tide – Why Now is a Strategic Inflection for Biopharma and Biotech More
  • ICYMI: CEO’s Perspective: Big Moves Come with Big Responsibility More
  • ICYMI: CEO’s Perspective: The High Cost of Job Hopping More
  • ICYMI: Elevating Executive Presence: A Blueprint for Life Sciences and Biotech Leaders More
  • ICYMI: The Power of Peer Learning - Why Even Top Biotech Leaders Need Mentorship More
  • ICYMI: What’s Next in Precision Medicine: Leadership Challenges and Opportunities More
  • Jeff Bluestone, Stephen Dilly Talk CEO Handoff, What’s Next for Sonoma; Scott Gottlieb’s Next Move More
  • The Rise of Fractional Talent in Life Sciences: What to Expect in 2026 More
2025 Advancing Drug Development Forum | Use code MP225 to Save $225 off! - 11 December 2025, UMass Club, Boston, MA

Event Center

Note: Events may be in any Big4Bio region or virtual
Biotech Showcase, Jan 12-14
Learn More  →
  • Compounding Pharmacy Compliance (Save 10% with VIP code: 25B4B10) Dec 9-10
  • PBM Contracting Summit (Save 10% with VIP code: 25B4B10) Dec 9-10
  • Trade and Channel Strategies (Save 10% with VIP code: 25B4B10) Dec 9-11
  • The Power of Presenting at Biotech Showcase Dec 10
  • Advancing Drug Development Forum Dec 11
  • Know Before You Go: AI in 2026 — Signals, Risks, and Real-World Impact (Pre-JPM Event) Jan 6
  • BLPN Investor Summit Jan 8-10

SEE FULL EVENT SCHEDULE AT THE BIOCALENDAR

Boston Sponsors

Follow us

Spotlights       Get Featured       Company Directory      News       Contact       Subscribe

You are receiving this email because you signed up for one of our newsletters at Big4Bio.com, signed up at one of our partner or sponsor events, or given as a gift subscription by your firm or organization. Unsubscribe

Big4Bio:Boston, all rights reserved 2025

© 2025 Big4Bio, a division of BigBio Communications. All rights reserved.