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June 5, 2026
T1D Week in Review (WiR):
your go to Friday highlight reel of T1D research.
Curating the scientific conversation in Type 1 Diabetes
Basic Science & Translational Papers
Format update: Preprints located at the end of each section
Adenosine as a modulator of human islet function and hypoxic tolerance
5/31/26
Nanofibrous Bioabsorbable Functionalized Scaffolds Augment Subcutaneous Islet Engraftment and Function in Mice
6/4/26
Cell type-specific expression and subcellular localization of the human insulin upstream open reading frame (INSU) protein in pancreatic β-cells
5/28/26
A Hormone Cell Atlas maps the human endocrine system at cellular resolution
5/28/26
Development and translational evaluation of a novel GPR119-targeted PET tracer for imaging pancreatic dysfunction in diabetes ABSTRACT
5/27/26
Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α-Cells
5/31/26
α/β-Hydrolase Domain Containing 5 Supports Glucose-Stimulated Lipolysis and Insulin Secretion in Pancreatic β-Cells
5/28/26
Pharmacology and nonclinical development of teplizumab, a first-in-class immunotherapy for delaying the onset of type 1 diabetes
4/21/26
Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells
6/2/26
Patient-derived induced pluripotent stem cells for precision modelling of monogenic beta cell disorders
6/2/26
Aberrant IL-21/STAT3 signaling disrupts regulatory T cell function and CD4+ T cell homeostasis in children with T1D
5/17/26
ETS1 activates heparanase transcription to drive intra-islet heparan sulfate degradation and macrophage-induced insulitis in type 1 diabetes
6/3/26
Alginate-Coated Collagen Hydrogel Tubes for Scalable Cell and Biotherapeutic Particle Manufacturing
6/2/26
Clinical Papers
Impact of Early Initiation of Automated Insulin Delivery on Glycemia Two Years from T1D Diagnosis
6/3/26
The role of biomarkers in early detection of type 1 diabetes
2026
Bringing early detection to life: real-world operationalization of a presymptomatic type 1 diabetes screening and monitoring pilot program
5/29/26
Sex differences in cardiovascular disease risk in type 1 diabetes: The vascular bed paradox in women
5/30/26
The use of automated insulin delivery system in people with type 1 diabetes and end stage kidney disease on hemodialysis
6/1/26
Associations between body composition and glycemic control: an exploratory analysis of bioelectrical impedance parameters in adolescents with type 1 diabetes
5/29/26
Time to resolution of diabetic ketoacidosis in children with T1D: a survival analysis of clinical predictors
5/29/26
Diabetes and Femoral Fracture Patterns: A Nationwide Registry Study
5/27/26
Increased Glycation Ratio and Risk of Complications in Latent Autoimmune Diabetes in Adults Compared With T1D Onset before 30 Years
5/28/26
Exploring the role of resistin as a biomarker of early renal changes in pediatric type 1 diabetes mellitus
5/26/26
Hyperglycemia metrics from continuous glucose monitoring are independently associated with platelet morphology in adults with T1D
6/1/26
Glycaemic Control by Sociodemographic Factors in Adults With Type 1 Diabetes in England: Trends From 2007-2008 to 2023-2024
6/2/26
Trends in Potentially Avoidable Hospitalisations Among People With Diabetes in Ireland; 2015-2024
5/31/26
Treatment burden and health-related quality of life in young adults with T1D
6/3/26
Impact of Removing Restrictive Haemoglobin A1C Eligibility Criteria for Insulin Pump Therapy Funding for Children With T1D in Ontario, Canada
5/28/26
A decade of insulin pump therapy in a Belgian paediatric diabetes centre: longitudinal outcomes and evolving practices
6/3/26
Three-Month Retreatment with Cyclosporine A for a Relapse of Type 1 Diabetes Mellitus after 5 Years of Remission
2026
Adopters and discontinuers: Mapping the diabetes device adoption journeys of adults with type 1 diabetes after continuous glucose monitoring uptake
5/28/26
T1D Data, -Omics, CGM, Tools
Increasing incidence of T1D in children and adolescents from 2012 to 2021 in Germany: trends before and during the COVID-19
6/2/26
Type 1 diabetes and risk of Parkinson's disease: A nationwide nested case–control study
5/29/26
Development of autoencoder-guided attention-LSTM models for predicting nocturnal hypoglycemia risk in T1D
6/1/24
The first epidemiological study of presymptomatic type 1 diabetes among first-degree relatives in Japan: PREP-T1D study
5/31/26
Association between Preexisting Type 1 and Type 2 Diabetes and Severe Maternal Morbidity
5/27/26
Prenatal exposure to ambient air pollution and the risk of type 1 diabetes in the offspring: a nationwide Danish study
6/1/26
Zero-shot automated insulin delivery for T1D via dynamic physiology-aware reinforcement learning
5/28/26
Lessons from Other Diseases
Kidney Transplantation after Clearing Anti-HLA Antibodies with CD19 CAR T Cells
6/3/26
Long-Term Outcomes and Follow-Up After Total Pancreatectomy with Islet Autotransplantation (TPIAT)
5/25/26
Therapeutic effect of T-cell engager in two patients with autoimmune neuropathy
5/30/26
Coordinated expression and assembly of BiP, p58IPK, and ER chaperone complexes maximize proinsulin folding in pancreatic β cells
6/1/26
Novel HLA class I and II insights into the pathogenesis of systemic sclerosis-associated interstitial lung disease
5/30/26
Epigenetic Profiling of Human Insulinomas Reveals AP-1 Family as Critical Regulators of Beta Cell Maturation
5/30/26
Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy
6/3/26
Stem cell-derived extracellular vesicles as immunomodulatory agents: targeting pathological crosstalk in SLE & MS
5/13/26
Autoantibodies in long COVID: A mechanistic foothold in a heterogeneous disease
5/28/26
PAX4 R192H variant impairs β cell function by disrupting β cell identity and compensatory capacity in response to metabolic stress
5/28/26
Integrated transcriptomic and epigenomic profiling reveals conserved molecular subtypes across systemic autoimmune diseases
5/30/26
Distinct senescent β-cell senotypes differentially drive islet aging and dysfunction
5/28/26
Identification of a shared antigen linking CD4+ T and B cell pathology in Sjögren’s disease
6/3/26
Risk of Autoimmune Hepatitis in Patients with IBD Treated with TNF Antibodies—Which Is Safer?
5/28/26
Current Causes of Death among Children and Adolescents in the United States
5/13/26
Temporal Single-Cell Transcriptional Dynamics of Murine Pancreatic Islet Remodeling During Hyperglycaemia Progression
6/1/26
Development and validation of a clinical prediction tool to identify adults with insulin-treated T2D and high C-peptide levels for potential insulin
5/28/26
Reviews & Op-eds
QUALITY CONTROL AND NON-CLINICAL TESTING OF IPSC- AND ESC-DERIVED MEDICINAL PRODUCTS
4/29/26
Type 1 Diabetes Management Beyond Insulin: Aligning Evidence, Research, and Regulation
5/26/26
Pathophysiology and Treatment of Type 1 Diabetes in Older Adults
6/4/26
NK cells in endocrine autoimmune disorders, current knowledge and implications for therapeutic strategies
2026
Towards mRNA therapeutics 2.0
6/3/26
Beyond Glycemia in T1D The Hidden Burden of Insulin Resistance and Cardiorenal Risk in Type 1 Diabetes—Part 1
5/27/26
Finerenone in Type 1 Diabetes and Chronic Kidney Disease- Correspondence
6/3/26
Efficacy and Safety of Once-Weekly and Once-Daily Basal Insulins in T1D
6/1/26
Toll-Like Receptors in Diabetes: Immunometabolic Mechanisms and Emerging Precision Therapeutic Strategies
5/29/26
Transcriptional and chromatin dynamics in macrophage differentiation and activation
5/29/26
Influence of islet purity on the proportion of smaller islets and graft outcomes in clinical transplantation
5/18/26
Type 1 Diabetes and Cardiovascular Risk: The Current Management Strategies
5/26/26
Regulatory T cells in cancer and inflammation
6/1/26
Synthetic gene circuits for gene- and cell-based precision therapy
6/2/26
THE POTENTIAL OF USING STEM CELL THERAPY TO TREAT TYPE 1 DIABETES thesis
2026
Regulatory & Business News
New Think Tanks on Demand
Upcoming conferences/meetings
