Each month, the NHS Blood and Transplant Systematic Review Initiative provides an overview of the most important new publications in transfusion medicine, enhanced with PICO Summaries.

All content is sourced from the Transfusion Evidence Library which is free to access worldwide.

Click here for the web version of the Transfusion Evidence Alert.

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Andexanet for factor Xa inhibitor-associated acute intracerebral hemorrhage.
Connolly, S.J., et al. (2024). The New England Journal of Medicine.
PICO Summary available

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The impact of social media intervention based on functional motivation on repeat blood donation behavior: A prospective randomized controlled trial study.
Gao, C., Mei, H., and Mao, X., (2024). Transfusion. [Record in progress].

The role of sealants for achieving anastomotic hemostasis in vascular surgery.
Ma, G.W., et al. (2024). The Cochrane Database of Systematic Reviews.

Predicting blood transfusion following traumatic injury using machine learning models: a systematic review and narrative synthesis.
Oakley, W., et al. (2024). The Journal of Trauma and Acute Care Surgery. [Record in progress].

Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support.
Radford, M., et al. (2024). The Cochrane Database of Systematic Reviews.

Recombinant ADAMTS13 in congenital thrombotic thrombocytopenic purpura.
Scully, M., et al. (2024). The New England Journal of Medicine.

Early cold stored platelet transfusion following severe injury: a randomized clinical trial. S
perry, J.L., et al. (2024). Annals of Surgery. [Record in progress].

A randomized trial of the inflammatory cytokines levels and the blood transfusion rate between miniaturized tubing group and conventional tubing group in congenital heart disease open heart surgeries.
Wang, P., et al. (2024). Perfusion. [Record in progress].

Quantitative blood loss measurement methods for early detection of primary postpartum haemorrhage following vaginal birth: a scoping review.
Wang, T., et al. (2024). Journal of Clinical Nursing. [Record in progress].

Andexanet alfa versus PCC products for factor Xa inhibitor bleeding: a systematic review with meta-analysis.
White, C. M., et al. (2024). Pharmacotherapy.

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The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion