Each month, the NHS Blood and Transplant Systematic Review Initiative provides an overview of the most important new publications in transfusion medicine, enhanced with PICO Summaries.

All content is sourced from the Transfusion Evidence Library which is free to access worldwide.

Click here for the web version of the Transfusion Evidence Alert.

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Effectiveness of ferritin-guided donation intervals in whole-blood donors in the Netherlands (FIND'EM): a stepped-wedge cluster-randomised trial.
Meulenbeld, A., et al. (2024). Lancet.
PICO Summary available

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A systematic review of the cost and cost-effectiveness of immunoglobulin treatment in patients with hematological malignancies.
Carrillo de Albornoz, S., et al. (2024). International Journal of Technology Assessment in Health Care.

Transfusion outcomes and clinical safety of ABO-nonidentical platelets transfusion: a systematic review and meta-analysis.
Cheng, Z., et al. (2024). Transfusion and Apheresis Science. [Record in progress].

Impact of early versus delayed umbilical cord clamping on term neonates' haemoglobin levels: a randomized controlled trial.
Enyinna, K.P., et al. (2024). The Journal of International Medical Research.

Effects of individualized anemia therapy on hemoglobin stability: a randomized controlled pilot trial in hemodialysis patients.
Fuertinger, D.H., et al. (2024). Clinical Journal of the American Society of Nephrology. [Record in progress].

A modified low-priming cardiopulmonary bypass system in patients undergoing cardiac surgery with medium risk of transfusion: A randomized controlled trial.
Gao, S., et al. (2024). Heliyon.

Hemostatic effects of tranexamic acid in cardiac surgical patients with antiplatelet therapy: a systematic review and meta-analysis.
Tian, L., et al. (2024). Perioperative Medicine.

Liberal or restrictive transfusion strategy in patients with traumatic brain injury.
Turgeon, A.F., et al. (2024). The New England Journal of Medicine. [Record in progress].

Proton-pump inhibitors to prevent gastrointestinal bleeding - an updated meta-analysis.
Wang, Y., et al. (2024). NEJM Evidence.

A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial. Williams, E.V., et al. (2024). Nature Medicine. [Record in progress].

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The Systematic Review Initiative (SRI) is a clinical research group established in 2001 by NHS Blood and Transplant (NHSBT) and funded by the UK Blood Services. The primary objective of the SRI is to “develop the evidence base for the practice of transfusion medicine”, by undertaking systematic reviews and other evidence-based medicine research projects in the transfusion field. @sritransfusion