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EDITOR'S NOTE: Big4Bio newsletters will not be published from Dec 16, 2025 to Jan 4, 2026; they will resume distribution on Monday, Jan 5, 2026.

December 12, 2025
Covering Life Sciences Drugs, Diagnostics, Devices, Digital Health
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Press Releases

  • AtaiBeckley: New U.S. Patent Granted for EMP-01, Strengthening Intellectual Property Portfolio More
  • BeyondSpring: ESMO Asia Presentation on Plinabulin + Docetaxel Improving Survival in Large Phase 3 DUBLIN-3 Asian Subset for EGFR WT NSCLC Compared to Docetaxel, Strengthening the Case for a Global Registration Path More
  • Glenmark Pharmaceuticals: To launch Leucovorin Calcium for Injection USP, 350 mg/vial Single-Dose Vial More
  • ImmuneWalk Therapeutics: Positive Results From Phase 1 SAD/MAD Study of IW-601, a First-In-Class Therapeutic With Broad Potential in Inflammatory and Autoimmune Diseases More
  • Mesoblast: Independent Study Presented at American Society of Hematology (ASH) Annual Meeting Concludes Remestemcel-L Superior to Ruxolitinib in Clinical Outcomes as Treatment for SR-aGvHD More
  • OKYO Pharma: New Data Showing Favorable Corneal Nerve Outcomes in Phase 2 Study for Neuropathic Corneal Pain More
  • Syndax: Revuforj (revumenib) Named Best New Drug at the Scrip Awards 2025 More
  • Tharimmune: Appoints Jacob Asbury as Chief Financial Officer to Advance Canton Coin Treasury Strategy More

Financial News

  • Cosette Pharmaceuticals: Termination of Proposed Acquisition of Mayne Pharma More
  • Cycle Pharmaceuticals: To Acquire Applied Therapeutics More
  • Get Full Access to BYTE51 Life Sciences Intelligence for 50% Off More
  • JPM Week Conference Readiness Packages (Big4Bio Subscriber Discount) More
  • More on Biotech Venture Firm Apple Tree Going Bankrupt Amid Disputing With Billionaire Backer More
  • Roivant Updates Investors on Mosliciguat Development Plans More*
  • Tevogen: CEO Supports Local Law Enforcement With Personal Contribution of 230,000 Company’s Shares of Common Stock More
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Media/Misc Coverage

  • BioPharmGuy News: Pre-Holiday Roast, New Flu Dropped, Purdue Tumbles, High Energy Decision More
  • More on Priority Review for Opdivo and Chemo in cHL More*
  • Subscribe to LifeSci Startup for Updates on US Startups More
  • The Big4Bio Podcast: Every Moment Matters: Integrating AI into Drug Discovery Podcast

Companies

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Career Center

M&A in Life Sciences: The Turning Tide – Why Now is a Strategic Inflection for Biopharma and Biotech
Learn More  →
  • Centessa CEO to Step Down; John Maraganore, Clive Meanwell Find CMO for Their New Cardio Bet More*
  • ICYMI: CEO's Perspective: Big Moves Come with Big Responsibilities More
  • ICYMI: CEO's Perspective: The High Cost of Job Hopping More
  • ICYMI: Elevating Executive Presence: A Blueprint for Life Sciences and Biotech Leaders More
  • ICYMI: The Power of Peer Learning: Why Even Top Biotech Leaders Need Mentorship More
  • ICYMI: What’s Next in Precision Medicine: Leadership Challenges and Opportunities More
  • 9 Companies Hiring in New Jersey More

Event Center

Note: Events may be in any Big4Bio region or virtual
Biotech Showcase, Jan 12-14
Learn More  →
  • Know Before You Go: AI in 2026 — Signals, Risks, and Real-World Impact (Pre-JPM Event) Jan 6
  • BLPN Investor Summit Jan 8-10

SEE FULL EVENT SCHEDULE AT THE BIOCALENDAR

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