They are two of the most recognisable voices in Australian sport, she the assured and personable anchor for ABC Radio's weekend Grandstand program, he an authoritative sports commentator for cricket, footy, the Olympics, Commonwealth Games and everything in between.
Karen Tighe and Glenn Mitchell are also husband and wife. Karen will be very familiar to MEDCON21 participants by the end of the three-day event, as she is the MC. Glenn is a keynote speaker, in his role as mental health advocate, having dealt with a major depression and suicide attempt.
But MEDCON21 will be something more for the couple. It's the first time Karen is plying her trade at a major event since encephalitis deprived her of her precious gift, a prodigious memory, almost 18 months ago.
It's been an unusual turn of events for the partners, after Karen turned carer for her stricken husband during his mental health challenge. They've worked closely together before but with Karen now on the comeback trail, MEDCON21 will be a significant milestone for the power couple. They will even share the stage for the question and answer session after Glenn's keynote address.
As sporting comebacks go, it's hard to think of any more satisfying than the one that will unfold for those attending MEDCON21.