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Domainex - Enrich your medicines pipeline
 

Domainex newsletter

All the latest news and industry insights from the Domainex team

 
 
 
Tom headshot

Tom Mander, CEO

Reflecting on the new year

We’re already into February (where does the time go?) but I hope everyone is having a good start to the year. 2021 was a record year for Domainex: growing as a company, celebrating our 20th anniversary and being awarded ‘Best Drug Discovery CRO’ were just a few highlights. 2022 promises to be even better. We have just announced our collaboration with Parkinson’s UK, which will focus on developing small molecule therapies targeting neuroinflammation. Also, last month we announced the exciting news that Queen’s University Belfast has entered into a collaboration and licensing agreement with Ipsen to progress a FLIP inhibitor programme which was supported by Domainex. There is more exciting news to come – watch this space! 

Thank you to our excellent team for all their hard work during 2021 and the beginning of 2022. As the new year gets into full swing, we can’t wait to support many more innovative drug discovery projects. 

I wish you all the best for 2022.

Parkinson's UK collaboration graphic

Parkinson’s UK and Domainex collaborate to develop therapies targeting neuroinflammation to slow the progression of Parkinson’s

Domainex and Parkinson’s UK have announced a collaboration focused on developing small molecule therapies targeting neuroinflammation that could slow the progression of Parkinson’s. Domainex will provide fully integrated drug discovery services including assay biology, medicinal and computational chemistry.

Read the full article
 
medicinal chemistry Domainex
 

Queen’s University Belfast enters agreement with Ipsen in FLIP inhibitor project supported by Domainex

The FLIP inhibitor programme has been supported by Domainex since its inception, including providing integrated medicinal chemistry services and assistance in securing a Wellcome Trust Seeding Drug Discovery award. Queen’s has now entered a collaboration and licensing agreement with Ipsen to research, develop, manufacture and commercialise FLIP inhibitors.

 
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One Nucleus Genesis

Rachel Pearce attended One Nucleus Genesis on behalf of Domainex and discussed science in person with old and new acquaintances.

 
Domainex CRO award logo
 

Domainex wins Best Drug Discovery CRO award

Domainex was awarded the Best Drug Discovery CRO 2021 in the Healthcare and Pharmaceutical Awards, marking two years of recognition in this sector.

 
Anticoagulant diagram
 

Medicinal Chemistry in Review

Factor XIa selective inhibitors as potential new anticoagulants for the treatment of thrombotic diseases.

 
Domainex team
 

Developing your career with Domainex

Welcome to Carlos Turrado García (Senior Scientist II, Chemistry), Carmina Micelli (Senior Scientist I, Protein Science), Fruzsina Hobor (Senior Scientist II, Protein Science), Hayley Jackson (Scientist, Protein Science), Ian Winfield (Team Leader, Assay Biology), Nima Abbasian (Senior Scientist I, Assay Biology), Phil Leonard (Team Leader, Protein Science) and Robina Akhtar (Financial Controller) who have all recently joined the Domainex team. And a huge congratulations to those of our team who have recently been promoted.

New publications

“Scar-in-a-jar”: in vitro assay for the quantification of key markers of fibrosis

Synthesis in Review: Understanding the latest developments in synthetic chemistry from Strain-Release enabled Friedel-Crafts Spirocyclisation to the single step conversion of amides to enamides

Medicinal chemistry in review: Overcoming PXR liability

Synthesis in Review: A look at the latest developments in synthetic chemistry from the direct deamination of primary amines to the gem-difluoroallylation of aryl halides and pseudo halides

Upcoming events

Biotechgate Digital Partnering: Virtual Business Development & Licensing Event
7th-11th February 2022 | Virtual
Providing a platform for business development in the field of licensing and collaboration.

8th RSC-BMCS Fragment-based Drug Discovery Meeting (Fragments 2022)
27th March 2022 | Cambridge, UK and Virtual
A look into fragment-based Drug Discovery case studies that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programmes.

ELRIG Research and Innovation
29th March 2022 | Oxford, UK
A conference discussing how cutting edge science continues to be identified and exploring how emerging technologies will enable this science to be translated into successful therapeutics.

Start your next project with Domainex

Contact one of our experts today
 
 
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Domainex is a registered company (number 4336899)
Chesterford Research Park
Little Chesterford
Saffron Walden, Essex
CB10 1XL, UK
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