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IDCRC Newsletter: April 2026

IDCRC Spotlight: Marcela F. Pasetti, PhD, Endpoint Laboratory Principal Investigator, University of Maryland School of Medicine

This month's IDCRC investigator spotlight features Marcela F. Pasetti, PhD, the Endpoint Laboratory principal investigator for the PROMISE and Measles study at the University of Maryland School of Medicine. Dr. Pasetti is an immunologist, professor of pediatrics, and also serves as the chief of the Applied Immunology Section at the Center for Vaccine Development.

Her research focuses on vaccines and immunology to understand how protective immunity can be induced in animal models and in humans following infection and vaccination, and the mechanisms involved. Her primary areas of interest are pediatric vaccines, neonatal and infant immunology, and maternal immunization. She investigates novel vaccine strategies, antigen delivery systems, adjuvants, and immunization regimens for protection against pathogens that affect young children, as well as the influence of maternal immunity on infant immune responses to vaccines, and the impact of vaccine combinations on long-term health and protection. 

headshot of Marcela F. Pasetti, PhD

"The IDCRC is unique in its capacity to advance clinical research. It supports high-complexity, rigorous clinical trials involving multiple sites. It brings together accomplished investigators of multiple disciplines and institutions."

READ THE FULL INVESTIGATOR SPOTLIGHT
 

Annual Meeting

2026 annual meeting banner with group photo from 2025

2026 IDCRC Annual Meeting is two weeks away!

The 2026 Annual Meeting is just two weeks away! We look forward to seeing many of our Leadership Group, VTEU members, and DMID colleagues for our two-day meeting. This year's robust program will highlight the numerous scientific accomplishments of the IDCRC and VTEUs and provide ample networking opportunities for members. 

Meeting Overview:

  • Date: May 13-May 14
  • Location: NIAID Building, 5601 Fishers Lane, Rockville, MD, 20892
  • Visit the Annual Meeting webpage for information, including meeting goals, draft agenda, accommodations, and local dining options.

Reminder: This will be an invitation-only meeting for members of the IDCRC (VTEU and LG) and DMID. All attendees (in person and virtual) must have registered to attend. Virtual attendees will receive the meeting login information prior to the meeting with the email address provided at registration. 

Questions? Contact idcrc@emory.edu for more information.

 

Annual Meeting Schedule of Events

Wednesday, May 13, 2026

9 a.m.-3:40 p.m. | Annual Meeting Day 1 and Poster Session
NIAID Building, 5601 Fishers Lane, Rockville, MD, 20892

3:45-5 p.m. | Breakout Sessions
NIAID Building, 5601 Fishers Lane, Rockville, MD, 20892

 
Exterior of NIH Clinical Center Building

(NIAID HQ in Rockville| Credit: NIAID)

6-7:30 p.m. | IDCRC Reception and Awards Ceremony
Canopy by Hilton Washington DC/Bethesda North, 940 Rose Avenue, North Bethesda, MD, 20852

Thursday, May 14, 2026

9 a.m.-2:30 p.m. | Annual Meeting Day 2
NIAID Building, 5601 Fishers Lane, Rockville, MD, 20892

Exterior of Canopy by Hilton Washington DC/Bethesda North

(Canopy by Hilton Washington DC/Bethesda North)

VIEW FULL PROGRAM SCHEDULE HERE
 

Help us capture this year's meeting!

Clip art of purple camera

Attending the Annual Meeting? Help us capture the day! Send us photos, including selfies, group photos, and highlights of the day, to be featured in our recap story!
Email us at idcrc@emory.edu.

SEND US YOUR PHOTOS
 

Publications

NOTE: Please include the following citation in any publications resulting from direct or indirect IDCRC support: 

"Supported by the Infectious Diseases Clinical Research Consortium through the National Institute for Allergy and Infectious Diseases of the National Institutes of Health, under award number UM1AI148684. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."

 

View recent publications and updated quick stats below:

  • Impact of prior SARS-CoV-2 acquisition on binding and neutralizing antibody responses following COVID-19 vaccination: A cross-protocol analysis of individual-level data from six phase 3 clinical trials
  • SARS-CoV-2 spike sequence-based distance as a marker of binding antibody response to COVID-19
  • The vaccine platform used for COVID-19 primary immunization shapes the quality of the human B cell response to a vaccine boost
Quick stats for IDCRC publications (updated as of 3.31.2026)
VIEW FULL PUBLICATIONS ARCHIVE
 

Training

IDCRC Mentee Profile: Lauren Jatt, MD

Lauren Jatt, MD, is an infectious diseases fellow at the University of Washington whose research focus is on vaccinology and immune correlates of protection. Her work integrates vaccine clinical trials, controlled human infection models, and high-dimensional immunologic profiling to understand why vaccines succeed or fail. 

Dr. Jatt is a member of the IDCRC's Mentorship Program cohort. This program provides mentoring and development opportunities for early-career investigators and fellows in clinical and translational infectious diseases research.

Headshot of Lauren Jatt

I am most looking forward to the opportunity to learn from and interact with leading vaccinologists through the IDCRC Mentorship Program. I am also excited to build lasting relationships with my cohort, developing a sense of camaraderie and a professional network that will serve as a source of collaboration, support, and shared learning throughout our careers.

READ THE FULL MENTEE SPOTLIGHT
 

News

NFID| There’s Nothing New About Applying a ‘Gold Standard’ to Vaccine Trials with Angela Branch, MD

Headshot of Angela Branch

Angela R. Branche, MD, associate professor of medicine at the University of Rochester, was a recent writer for the National Foundation of Infectious Diseases (NFID)'s guest blog post on the rigorous standards for vaccine clinical trials. 

 

Many vaccines are initially tested in randomized trials with placebo or comparison groups. But once a safe, effective vaccine is available, using a placebo would be unethical, as it leaves participants unprotected. Imagine testing a new blood pressure medication by withholding standard treatment from some patients who need it.

So let me, a vaccinologist who has participated in many clinical trials, shed some light on this issue. Vaccine trial design begins with understanding the disease. Clinician-scientists who treat patients and study epidemiology help identify who needs protection and why, and often lead trial design, working with the National Institutes of Health, Centers for Disease Control and Prevention (CDC), and industry partners to ensure that the best science is being done to develop vaccines that protect those most at risk.

READ FULL BLOG POST HERE
 

IDSA | Let's Talk ID with Buddy Creech, MD, MPH, FPIDS

Check out the new Let's Talk ID featuring host Buddy Creech, MD, MPH, FPIDS, who is joined by pediatric infectious diseases fellows to explore what it takes to be an effective vaccine advocate, from patient conversations to policymaking.

They discuss the importance of clear communication, building trust, and advancing policies that protect equitable access to vaccines.

LISTEN TO THE EPISODE HERE
 

The American Association for the Advancement of Science
(AAAS) announces 2025 Fellows

headshots of Igho Ofotokun and Carlos del Rio

We're pleased to share that two IDCRC network members (both current and former) were named in the American Association for the Advancement of Science (AAAS) 2025 Class of Fellows. Congratulations to the following individuals: 

Igho Ofotokun, MD, MSc, former IDCRC MCDC co-chair, was selected for his distinguished contributions to the field of HIV medicine, enhancing knowledge of post-infection sequelae and age-related end-organ damage biology and burden.

Carlos del Rio, MD, MACP, FIDSA, Emory VTEU principal investigator, was selected for describing the HIV care cascade and conducting studies that have led to the incorporation of HIV testing into care and improved linkage for persons with HIV.

AAAS selects Fellows for their outstanding efforts in the advancement of science based on research, teaching, administration, and technology, as well as communicating and interpreting science to the public. Becoming an AAAS Fellow is considered a lifetime honor. In addition to advancing research, Fellows play a crucial role in shaping public policy and influencing national and global perspectives on critical issues.

VIEW FULL PRESS RELEASE
 

Job Postings

Newly Posted! Infectious Diseases Research Job Openings

  • Center for Anti-Infective Research and Development (CAIRD), Hartford Hospital - Antimicrobial Research and Infectious Diseases Fellowship
  • Centers for Disease Control and Prevention - Biologist
  • Great Hill Solutions, LLC/Seneca Nation Group (SNG) - Epidemiologist III
  • Virginia Commonwealth University  - Open Rank Faculty - Infectious Disease Epidemiology
  • Washington University in St. Louis - Staff Scientist - Infectious Diseases

Visit the IDSA Career Center to browse other ID job postings.

 

Events

Harvard Medical School: Infectious Diseases in Adults 2026

Infectious Diseases in Adults 2026
Monday, May 4-Friday, May 8
Attend online via live streaming

Harvard Medical School logo

Infectious Diseases in Adults 2026 provides state-of-the-art approaches for the prevention, diagnosis, and management of infectious diseases: common, challenging, rare, and emerging. Hear directly from world-renowned specialists and master clinicians on state-of-the-art methods to diagnose, treat, and prevent infectious diseases. This program comprehensively covers best practices for common, emerging, rare, and the most challenging diseases. 

VIEW SCHEDULE AND REGISTER
 

Infectious Disease Board Review Course

Infectious Disease Board Review Course logo

2026 Infectious Disease Board Review: Live/Virtual Course
Saturday, August 22-Thursday, August 26
Attend in person at the Ritz-Carlton, Tysons Corner, or virtually via live stream.

This course is designed to help physicians prepare for the American Board of Internal Medicine (ABIM) Infectious Disease certification and recertification exams. This comprehensive program includes web access to the entire archived course plus primers and study guides, online-only lectures, photo-based questions, and over 500 ABIM-style questions.

LEARN MORE AND REGISTER
 

Funding Opportunities

2026 Deadline: 

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed) 
Deadline: May 15, 2026  

Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)  *NEW*
Deadline: June 4, 2026

WashU Medicine faculty for Pilot and Feasibility Research Projects  
Deadline: June 29, 2026 

Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and Non-Protein Targets for the Development of Novel Anti-Infectives
Deadline: Friday, July 17, 2026

Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses  
Deadline: Friday, July 17, 2026

Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)  
Deadline: Friday, August 7, 2026

2027 Deadline:

Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) 
Deadline: Wednesday, April 6, 2027

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) 
Deadline: Saturday, May 8, 2027

Notice of Special Interest (NOSI): Systems Modeling of Infection and Immunity Across Biological Scales 
Deadline: Wednesday, September 8, 2027

NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed  
Deadline: Wednesday, September 8, 2027

Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Universal Influenza Vaccine 
Deadline: Sunday, November 17, 2027

Notice of Special Interest (NOSI): Accelerating Malaria Vaccine and Monoclonal Antibody Discovery 
Deadline: Sunday, November 17, 2027

 

IDCRC Studies

Fully Enrolled Studies in Follow-up

  • A Randomized, Double-Blind, Placebo-Controlled Phase 1 Trial to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of Sanaria(R) PfSPZ-LARC2 Vaccine, a Late-Arresting, Replication-Competent, Genetically Attenuated Plasmodium Falciparum Vaccine by Controlled Human Malaria Infection in Malaria-Naïve Healthy Adults Conditions (DMID 23-0010)
  • Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults (DMID 23-0006)
  • A Phase 1 Trial to Evaluate the Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine, HydroVax-001B WNV in Healthy Adults (DMID 24-0008)

  • A Prospective, Randomized, Open-label Phase 4 Study of the Immunology and Safety of Maternal RSV Vaccination (ABRYSVOTM), Infant Nirsevimab (BEYFORTUSTM) Immunization, or Both Products During the First Year of Life (PROMISE) (DMID 24-0003)
IDCRC ACTIVE AND COMPLETED STUDIES
 

IDCRC Concept Quick Stats

ICP Status

  • Approved: 70

  • Administratively Not Supported: 29

  • Not Approved: 77

  • EWG Review: 2

  • EWG Liaisons: 0

  • EMT Concurrence: 0

  • Withdrawn: 23

  • Hold: 0

  • Moved to Active Study: 7

EWG Assignment

  • COVID: 92

  • Respiratory: 50

  • Emerging Infections: 22

  • Enteric Inf.: 12

  • Malaria and Tropical Dis.: 13

  • Sexually Transmitted Infections: 19

  • Mpox: 7

ECP Status

  • EWG Review-In Process: 0

  • EMT Review: 0

  • Approved-moved to Prioritization: 1

  • Not Approved: 29

  • Approved-moved to Protocol development: 2

  • Active Study: 7

  • EMT Vote: 0

  • Study in Protocol Development: 5

  • Study Closed (LSLV Complete): 9

  • Other: 11

IDCRC STUDIES
 

Communication Resources

COMMUNICATION TOOLKIT
 

Please submit IDCRC news to idcrc@emory.edu for inclusion in the monthly newsletter and IDCRC.org.

VISIT IDCRC WEBSITE
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