Tuesday, September 10, 2019
Reminder: Research Resources 101- Emory Integrated Genomics Core (EIGC)
Thursday, 9/19 at noon in SOM 190P Lyra Griffiths, PhD (Associate Scientist and Core Director) will present this seminar with the following objectives: - To understand the role of integrated cores at Emory
- To understand the services that the Emory Integrated Genomics Core provides including single cell sequencing.
- To learn how to contact the Emory Integrated Genomics Core and how to place an order
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Register Now! 2019 Department of Medicine Research Day
Friday, 11/1 from 7:30 a.m. to 5 p.m. in Cox Hall Ballroom. The full-day program includes both oral and poster presentations as well as a keynote address titled “Seizing unprecedented opportunities in discovery science” from Gary Gibbons, MD Director, National Heart, Lung, and Blood Institute at the National Institutes of Health. Awards are given at the conclusion of the day to recognize the most outstanding presentations. Register | Agenda | Read more Study participants needed! Healthy volunteers needed to immune reaction to flu vaccine
Requirements: Healthy males and females between the ages of 18 and 49 years of age who are interested in receiving an FDA approved flu vaccine and participating in follow-up lab studies to measure the body’s immune response to vaccination. Participants could not have been vaccinated with the flu vaccine with in the past 3 years. Read more (PDF) Notice of Special Interest: High-priority research topics for PA-19-053 and PA-19-056
This Notice invites applications on research employing genetically defined and/or modified mouse models, other animal models such as dogs and monkeys, or archived human joint tissues to explore the biological mechanisms underlying the initiation and progression of osteoarthritis. Read more Notice of Special Interest: Administrative supplements to support emerging physician- scientists to develop research expertise in Diabetes, Endocrinology, and metabolic diseases
The purpose of the NIDDK’s Division of Diabetes, Endocrinology and Metabolic Diseases (DDEMD) Administrative Supplement Program is to enable additional clinical perspectives to be brought to on-going research projects within the Division's mission and to enhance the research expertise of selected physicians. Read more Need help navigating the Department of Medicine Research Administration Service (RAS) Unit? The DOM RAS Unit has issued a one-page document to assist you in working your way
through the grant submission process starting with pre-award. Download PDF
National Institute on Aging Clinical Research Study Investigators toolbox: The purpose of the NIA Clinical Research Toolbox is to provide a Web-based informational repository for investigators and staff involved in clinical research. The Toolbox contains templates, sample forms, guidelines, regulations and informational materials to assist investigators in the development and conduct of high-quality clinical research studies. Read more
Funding & Award Opportunities
Weekly NIH funding opportunities and notices
Federal funding opportunities for public health faculty
Searchable database of internal medicine funding opportunities Patient Centered Outcomes Research Institute (PCORI) Improving healthcare systems research grants
Deadline: Tuesday, 10/1 (LOI) Improving Healthcare Systems Research Grants will offer for research that studies the comparative clinical effectiveness of alternative features of healthcare systems that are intended to optimize the quality, outcomes, and efficiency of patient care and that have the greatest potential for sustained impact and replication within and across healthcare systems. Read more Prevention of Lower Urinary Tract Symptoms (PLUS) research consortium clinical research centers (U01 clinical trial optional)
Deadline: Monday, 10/7 The Prevention of Lower Urinary tract Symptoms (PLUS) Research Consortium will use qualitative and quantitative strategies to conduct collaborative, transdisciplinary studies to establish the scientific basis for future intervention studies to promote bladder health and prevent lower urinary tract symptoms (LUTS) and associated bladder conditions such as bladder infections, urinary incontinence, voiding dysfunction, overactive bladder and interstitial cystitis/bladder pain syndrome in adolescent and adult women across the life course. Read more Planning grant for global infectious
disease research training program (D71 clinical trials not allowed)
Deadline: Friday, 10/11 The overall intent of this funding opportunity is to support a LMIC-US collaborative planning process that will prepare faculty and design advanced courses and resources for a research training program to enhance capacity at LMIC institutions to conduct research directly related to prevention, treatment and control of infectious diseases causing major morbidity and mortality. Read more Trans-agency blood-brain interface program (R61/R33- clinical trials not allowed)
Deadline: Monday, 12/2 This Funding Opportunity Announcement (FOA) will support high risk/high reward research on the blood/vascular component and regulation of the neurovascular blood unit (aka. Blood-Brain Barrier; BBB) in normal and pathological states to stimulate the development of a new field of science and re-define the neurovascular unit to also include the blood/vascular component to identify targets for diagnostics and regulation of the Blood-Brain Interface. Read more Myeloid- Deprived Suppressor Cells (MDSCs) as potential therapeutic targets in TB/HIV (R01 and R21 clinical trial not
allowed)
Deadline: Monday, 1/20/20 The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for support of innovative clinical, preclinical and non-clinical research to determine the potential of MDSCs as a target for host-directed therapeutics for tuberculosis in the context of HIV co-infection, and to better understand the role of host-induced immunosuppression in the progression of Mycobacterium tuberculosis pathogenesis. Read more
Camille Vaughan (General Medicine and Geriatrics) received funding from the NIA for a R34 entitled, “Coexisting nocturia and insomnia in older adults: Planning a trial of integrated therapy.”
Colleen Kelley (Infectious Diseases) received funding from the NIAID for a R01 entitled, “Understanding the rectal mucosal effects of cross-sex hormone therapy among US and Thai transgender women.” Wendy Book (Cardiology) received funding from the CDC for a project entitled, “Surveillance of congenital heart defects among children, adolescents, and adults.” Have you or a colleague recently received an award or grant funding?
Division Research Seminars
Thursday, 9/12 at 7:30 a.m. in the Wesley Woods Health Center, 5th Floor Conference Room
Geriatrics Research Seminar: “CONCERN Network- Cancer Oncology Emergency Research Network: Opportunities for collaboration" (Tammie E. Quest MD)
Thursday, 9/12 at 8 a.m. in the Grace Crum Rollins Building, Rita Anne Rollins Room, 8th Floor, SPH
Infectious Diseases Seminar: "Explaining racial differences in HIV viral suppression among MSM in Atlanta” (Patrick Sullivan, DVM, PhD)
Thursday, 9/12 at 8 a.m. in Whitehead, Conference Room 200
Pulmonary Division Research Seminar: “Therapeutic targeting of age-associated pathological mechanisms in pulmonary fibrosis” (Louise Hecker, PhD, University of Arizona College of Medicine)
Monday, 9/16 at 5 p.m. in Woodruff Memorial Research Building, Room 317
Endocrine Conference: “Adjunctive therapies to insulin for patients with Type 1 diabetes” (Guillermo Umpierrez, MD)
Recent Notable Publications
Igancio Sanz (Immunology)
Dale GA, Wilkins DJ, Bohannon CD, Dilernia D, et al. “Clustered mutations at the murine and human IgH locus exhibit significant linkage consistent with templated mutagenesis." J Immunol. 2019 Sep 1;203(5):1252-1264. Read more
Jeff Sands (Renal Medicine)
Sands JM. “Translating kidney fibrosis: Role of the EP2 receptor."Acta Physiol (Oxf). 2019 Sep;227(1):e13318. Read more Guillermo Umpierrez (Endocrinology)
Ledesma G, Umpierrez GE, Morley JE, Lewis-D'Agostino D, et al. “Efficacy and safety of lingaliptin to improve glucose control in older people with type 2 diabetes on stable insulin therapy: A randomized trial.” Diabetes Obes Metab. 2019 Jul 12. Read more Alberto Moreno (Infectious Diseases)
Arsiwala A, Varner C , McCaffery JN , Kell A, at al. “Nanopatterning protein antigens to refocus the immune response.” Nanoscale. 2019 Aug 15;11(32):15307-15311. Read more Laura Plantinga, Stephen Pastan, Rachel Patzer (Renal Medicine)
Hamoda RE, McPherson LJ, Lipford K, Jacob Arriola K, et al. “Association of sociocultural factors with initiation of kidney transplant evaluation process.” Am J Transplant. 2019 Jul 6. Read more
Pediatric Research Grand Rounds: “From engineered human heart tissue models to gene therapy for inherited heart disease”
Wednesday, 9/11 at 8 a.m. in Egelston (1405 Clifton Road NE) Classroom 5 William T. Pu (Professor of Pediatrics, Harvard Medical School, Director of Basic and Translational Cardiovascular Research, Department of Cardiology, Boston Children’s Hospital). Read more Emory IRB webinar: "Data migration dates, revised documents for new submissions and other news!" Thursday, 9/12 at noon The presentation will last approximately 20 minutes, including time for questions and answers. The session will be recorded for future reference. Read more Last Chance: September K-Club: “The fundamentals of finding funding: Considerations and strategies to find research funding that’s right for you”
Monday, 9/16 at noon in Egelston Classrooms 5-7 Nicole Crowell, MS, grant proposal development associate at Emory University presents this seminar. Read more Lunch and Learn: Controlled Substances and Dangerous Drugs
Tuesday, 9/24 at noon in the Nursing School Room 108 Topics include: storage, record keeping, license information, what to do when leaving the lab and reverse distribution. Space is limited so register quickly. Register | Questions
Reminder: Health Services Research Center (HSRC) Lunch and Learn
Wednesday, 9/25 at noon in SOM 190P Join the HSRC for an interactive Q&A on major federal sources for funding health services research, including AHRQ, PCORI, VA HSR&D, and the NIH. The panel includes: Rachel Patzer (Director Health Services Research), Neal Dickert (Associate Professor- Cardiology), Laura Plantinga (Assistant Professor- Renal Medicine), Camille Vaughan (Associate Professor- General Medicine/Geriatrics). Register | Read
more Think BIG Symposium Series- “The promise of precision medicine: Harnessing new technologies for public health impact”
Thursday, 10/31 from 12:15-1:15 p.m. in the Claudia Nance Rollins Auditorium, Rollins School of Public Health Dr. Gary Gibbons (Director, National Heart, Lung, and Blood Institute at the National Institutes of Health) presents this exciting topic. Register | Read more
Ali Kashkouli, MD
Division of Nephrology What is your professional background?
I completed my residency and chief residency at Emory University prior to a three-year research fellowship at the University of California, San Diego. I worked with Dr. Roland Blantz and Dr. Scott Thomson on the intricacies of tubuloglomerular feedback with incretin administration. I returned to Emory in 2011, and I am currently the Assistant Chief of Nephrology at the VA Medical Center.
In what division do you work, and who is your mentor?
I am an Assistant Professor in the Division of Nephrology. My mentor is Dr. Robert Steiner, UC San Diego, Division of Renal Transplant, also an avid fisherman who recently wreaked havoc on the aquatic life of upper New Hampshire. He is not only a mentor, but a friend. He is probably the most responsible for how I think through any medical problem. Briefly describe your research. Why is it important?
I am currently involved in a renal denervation trial using alcohol ablation for patients with resistant hypertension. Assuming the results are positive this sort of technology will be a boon to any patient who cannot control their blood pressure with diet and medications alone. What do you like most about Emory?
The people. The Emory community at large is a tightknit bunch that is difficult to replicate. What do you like to do in your spare time?
I publish the occasional article in online humor magazines. Literally 10’s of people have read my work.
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