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IDCRC Newsletter: November 2025

During this season of gratitude, we want to thank all of our IDCRC members and partners for an excellent year so far. We extend our heartfelt appreciation to each of you for your hard work and remarkable contributions to our network. We hope that you take the time over the next week to relax and enjoy the holiday!

 

Enteric Infections (EWG) Group Co-Chair Announcement

Congratulations to Jennifer Whitaker, MD, MSc, on being named the next Enteric Infections EWG co-chair.  She assumes this role as Mark Mulligan, MD (NYU Langone Health) has stepped down due to his retirement. She joins Wilbur H. Chen, MD, MS, (University of Maryland), to co-chair this group.

Dr. Whitaker is an associate professor of Molecular Virology and Microbiology, as well as Medicine, within the section of Infectious Diseases at Baylor College of Medicine (BCM). She has been an investigator within the BCM VTEU since 2019. 

When asked what she looks forward to in her new role, she shared the following sentiments.

I have been a member of the Enteric EWG since 2020, initially serving as an early career member through the IDCRC mentoring program. I have learned so much from the EWG chairs and team members over the years. I am excited to see the completion of studies that were prioritized for implementation. I enjoy collaborating with colleagues across multiple institutions and look forward to working with the EWG co-chair, Dr. Chen!

READ THE FULL ANNOUNCEMENT HERE
 

IDCRC Spotlight: PROMISE Study
Site Principal Investigator, Jennifer Nayak, MD

Headshot of Jennifer Nayak, MD

This month's IDCRC investigator spotlight is Jennifer Nayak, MD (University of Rochester), site principal investigator for the PROMISE study. This study is evaluating the effects of maternal vaccination and infant monoclonal antibody administration on RSV antibody levels in mothers and infants, providing essential insights into how these interventions function independently and in combination.

"The strength of the IDCRC lies in its flexibility and inclusiveness, which enable the network to rapidly respond to emerging infectious threats through research spanning the entire human lifespan. This adaptable infrastructure is vital for addressing infectious diseases that are newly emerging or increasing in prevalence."

READ DR. NAYAK'S FULL SPOTLIGHT
 

New Webpage: Additional VTEU Studies 

We have a new webpage! In addition to the IDCRC studies that are listed on our studies page, the VTEUs are recruiting for clinical trials at their institutions. 

For more details on enrolling in studies, please visit the Additional VTEU Studies page here. 

Additional VTEU studies webpage screenshot
ADDITIONAL VTEU STUDIES WEBPAGE
 

Annual Meeting

Save the Date: 2026 Annual Meeting

Save the date! Next year's IDCRC Annual Meeting will take place on Wednesday, May 13, and Thursday, May 14, 2026. We look forward to seeing everyone then. Stay tuned for more details!

ANNUAL MEETING WEBPAGE
 

News

IDSA Let's Talk ID Podcast | Live from IDWeek 2025: Infectious Diseases Hot Takes with Buddy Creech, MD, MPH, FPIDS,

Let's Talk ID logo

Let's Talk ID hosts, Buddy Creech, MD, MPH, FPIDS, Mati Hlatshwayo Davis, MD, MPH, FIDSA, and Paul Sax, MD, FIDSA, reunited live at IDWeek 2025 and discussed their hottest takes on infectious diseases and public health. Topics ranged from the controversial dismantling of the CDC to exciting breakthroughs in treating Staph aureus bacteremia, as well as shifts that could shape the future of the field.

LISTEN TO THE EPISODE HERE
 

AAMC | Outbreaks of measles are fueled by outbreaks of mistrust with Adam Ratner, MD, MPH

The day in 2018 that a child with measles showed up at his New York City hospital was a watershed moment for infectious disease specialist Adam J. Ratner, MD, MPH. Part of the measles outbreak that emerged from Orthodox Jewish communities in Brooklyn and New York’s Rockland County, it heralded a comeback of the highly contagious disease in communities around the country that continues today.

Adam Ratner presenting at e AAMC Annual Meeting, on Tuesday, November 4

“What I learned over the ensuing months changed the way that I thought about vaccines, about how we communicate, and about what measles in particular, but vaccine-preventable diseases in general, mean in terms of how we think about public health,” he told attendees of the session, “Outbreak of Mistrust: What Measles Teaches Us Now,” at Learn Serve Lead 2025: The AAMC Annual Meeting, on Tuesday, November 4.

READ FULL ARTICLE HERE
 

WXXI News NPR | Medical professionals set the record straight on vaccines with Ann Falsey, MD

Medical professionals set the record straight on vaccines

Childhood vaccination rates are falling across the United States. NBC News reports that since 2019, more than three-quarters of American counties have seen declines. Some places have dropped 20 to 40 percentage points. The number of school children granted exemptions from vaccination requirements is rising, too.

Three Rochester-area doctors joined "Connections with Evan Dawson" to set the record straight on vaccine claims Dr. Weinberg, UR Medicine; Dr. Steven Schulz, Rochester Regional Health; and Dr. Ann Falsey, UR Medicine.

LISTEN TO THE CONVERSATION HERE
 

University of Maryland School of Medicine News | New Vaccine Shows Promise Against Typhoid and Invasive Salmonella in First Human Trial with Wilbur H. Chen, MD

Researchers at the University of Maryland School of Medicine’s Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella, two major causes of illness and death among children in sub-Saharan Africa. Results were published in the journal Nature Medicine on October 8, 2025.

headshot of Wilbur Chen
READ FULL PRESS RELEASE
 

Job Postings

Newly Posted! Infectious Diseases Research Job Openings

  • Gilead Sciences - Senior Director, Epidemiology 
  • Virginia Commonwealth University School of Medicine - Post-Doctoral Fellow - Department of Microbiology and Immunology 

  • The University of Texas MD Anderson Cancer Center - Postdoctoral Fellow - Infectious Disease & Infection Control-Research 

  • Tulane University School of Medicine - Tenure Track Faculty, Microbiology and Immunology 

Visit the IDSA Career Center to browse other ID/HIV Medicine job postings.

 

Funding Opportunities

2026 Deadline: 

Notice of Special Interest (NOSI): Complement in Fundamental Immunology 
Deadline: Tuesday, January 7, 2026

Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine 
Deadline: Thursday, January 15, 2026

Georgia CTSA TL1 (T32-like) Clinical and Translational Research Training Program 
Deadline: Tuesday, February 17, 2026

Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)  *NEW*
Deadline: Wednesday, February 18, 2026

Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives
Deadline: Friday, July 17, 2026

Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses  
Deadline: Friday, July 17, 2026

Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)  
Deadline: Friday, August 7, 2026

2027 Deadline:

Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) 
Deadline: Wednesday, April 6, 2027

Notice of Special Interest (NOSI): Systems Modeling of Infection and Immunity Across Biological Scales 
Deadline: Wednesday, September 8, 2027

Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Universal Influenza Vaccine 
Deadline: Sunday, November 17, 2027

Notice of Special Interest (NOSI): Accelerating Malaria Vaccine and Monoclonal Antibody Discovery 
Deadline: Sunday, November 17, 2027

 

IDCRC Studies

Active Studies Recruiting Volunteers

  • A Phase 4 Study of a 3-Day vs. 7-Day Regimen of Doxycycline for the Treatment of Chlamydial Infection (DMID 22-0019)

Fully Enrolled Studies in Follow-up

  • A Randomized, Double-Blind, Placebo-Controlled Phase 1 Trial to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of Sanaria(R) PfSPZ-LARC2 Vaccine, a Late-Arresting, Replication-Competent, Genetically Attenuated Plasmodium Falciparum Vaccine by Controlled Human Malaria Infection in Malaria-Naïve Healthy Adults Conditions (DMID 23-0010)
  • Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults (DMID 23-0006)
  • A Phase 1 Trial to Evaluate the Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine, HydroVax-001B WNV in Healthy Adults (DMID 24-0008)

  • Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine (DMID 22-0020A)

  • A Phase 1, Randomized, Placebo-Controlled, Double-Blind Study to Assess the Safety and Pharmacokinetics of a Single Ascending Dose of EV-D68-228 in Healthy Adult Volunteers (DMID 23-0005)

  • A Prospective, Randomized, Open-label Phase 4 Study of the Immunology and Safety of Maternal RSV Vaccination (ABRYSVOTM), Infant Nirsevimab (BEYFORTUSTM) Immunization, or Both Products During the First Year of Life (PROMISE) (DMID 24-0003)
IDCRC ACTIVE AND COMPLETED STUDIES
 

IDCRC Concept Quick Stats

ICP Status

  • Approved: 70

  • Administratively Not Supported: 29

  • Not Approved: 77

  • EWG Review: 2

  • EWG Liaisons: 0

  • EMT Concurrence: 0

  • Withdrawn: 23

  • Hold: 0

  • Moved to Active Study: 7

EWG Assignment

  • COVID: 92

  • Respiratory: 50

  • Emerging Infections: 22

  • Enteric Inf.: 12

  • Malaria and Tropical Dis.: 13

  • Sexually Transmitted Infections: 19

  • Mpox: 7

ECP Status

  • EWG Review-In Process: 0

  • EMT Review: 0

  • Approved-moved to Prioritization: 1

  • Not Approved: 29

  • Approved-moved to Protocol development: 2

  • Active Study: 7

  • EMT Vote: 0

  • Study in Protocol Development: 5

  • Study Closed (LSLV Complete): 9

  • Other: 11

IDCRC STUDIES
 

Communication Resources

COMMUNICATION TOOLKIT
 

Please submit IDCRC news to idcrc@emory.edu for inclusion in the monthly newsletter and IDCRC.org.

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