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IDCRC Newsletter: October 2025

IDCRC Publishes Supplement in Clinical Infectious Diseases (CID)

CID Supplement cover

The IDCRC is proud to announce publication of the supplement, “Infectious Diseases Clinical Research Consortium (IDCRC) and Vaccine and Treatment Evaluation Units (VTEUs): A Review,” in Clinical Infectious Diseases (CID).

This supplement, guest-edited by Nadine Rouphael, MSc, MD, chair of the Publications Key Function Committee and Emory VTEU principal investigator, features a range of articles that explore key aspects of the network’s history, structure, achievements, innovations, and lessons learned.

It highlights the value and impact of the collaborative partnerships among the National Institute of Allergy and Infectious Diseases (NIAID), the IDCRC Leadership Group, and the IDCRC VTEUs, as well as the global network of partner sites, all working together to improve the treatment and prevention of infectious diseases and to respond effectively to public health emergencies.

READ THE FULL ANNOUNCEMENT HERE
 

IDCRC shines at IDWeek 2025

IDWeek 2025 was held earlier this month in Atlanta, GA, from October 19-22. More than 11,000 infectious disease health professionals from various institutions and backgrounds worldwide gathered to collaborate, connect, and learn from each other’s expertise in patient care, research, and public health.

"The conference provided a perfect venue to connect with Peds and Adult ID colleagues and to hear updates on cutting-edge research advances in ID. At the same time, it was a sobering reminder of the many challenges that absent colleagues from the U.S. CDC and military continue to face in doing their work. While we celebrated achievements and successes, we acknowledged the obstacles that we must overcome together to achieve all that we can for public health." — Matthew B. Laurens, MD, MPH, University of Maryland

The IDCRC was well represented, with 42 presentations delivered by our members.

We are proud to highlight a few of these individuals below and many more in the full recap story on the IDCRC website.

  • IDCRC mentoring cohort members Paulina Sudnik, MD, and Cristina Tomatis Souverbielle, MD, each delivered a poster presentation. 
  • Robert Frenck, MD, Cincinnati Children’s Hospital Medical Center VTEU PI, Christina A. Rostad, MD, director of the Emory Children’s Center Vaccine Research Clinic, and Jennifer Whitaker, MD, MSc, Baylor VTEU investigator, served as panelists in an interactive session titled “Challenging Vaccine Issues: Beyond the Guidelines,” moderated by C. Mary Healy, MD, COU co-director and Flor Munoz, MD, Baylor VTEU investigator. 

Congratulations again to our VTEU partners and IDCRC members on being selected for these opportunities! 

VIEW FULL LIST OF PRESENTERS
READ FULL RECAP STORY HERE
 

Spotlight: "LARC2" Study Protocol Co-Chair, Sean C. Murphy, MD

This month, we're excited to spotlight, Sean C. Murphy, MD, PhD, protocol co-chair for the Phase 1 Clinical Trial for Experimental Malaria Vaccine (LARC2 Study). This study aims to evaluate the safety, immunogenicity, and efficacy of the Sanaria® PfSPZ-LARC2 vaccine, which is a late-arresting, replication-competent, genetically attenuated form of Plasmodium falciparum, through controlled human malaria infection in malaria-naïve healthy adults.

Headshot of Sean Murphy

Dr. Murphy is an assistant director of clinical microbiology and associate professor of laboratory medicine at the University of Washington (UW) School of Medicine. Dr. Murphy’s work focuses on the immune response to complex infectious diseases and on diagnostic test development. The major focus of the laboratory is malaria infection of humans and animal models by Plasmodium parasites.

"Because of the collaboration across IDCRC, NIH, and the VTEUs, we are able to continue to advance malaria vaccines, critical to maintain support and focus in our collective fight against this hugely important parasite. Malaria is mostly thought of as a tropical disease, but it is important to remember that 100 years ago there were over one million cases annually in the U.S. (i.e., the conditions can exist for transmission here) and even this year and in the past few years there have been cases of malaria transmitted by local mosquitoes in the U.S. to Americans who had not traveled outside of the U.S."

READ DR. MURPHY'S FULL SPOTLIGHT
 

Annual Meeting

Put it on your calendar: 2026 Annual Meeting

Save the date! Next year's IDCRC Annual Meeting will take place on Wednesday, May 13, and Thursday, May 14, 2026. We look forward to seeing everyone then. Stay tuned for more details in early next year!

ANNUAL MEETING WEBPAGE
 

Training

IDCRC Mentee Profile: Andrew B. Flemimg, MD

headshot of Andrew Fleming

Andrew B. Fleming, MD, is an assistant professor in the Division of Infectious Diseases & Immunology at NYU Langone. He has a special interest in emerging infections and zoonotic pathogens, and has worked on vaccines against Lyme disease and avian influenza.

Dr. Fleming is a member of the IDCRC's Mentorship Program cohort. He shares what he looks forward to as a member of the IDCRC's Mentorship Program below.

"I’m very grateful to be included in the IDCRC mentorship program. I look forward to learning from all my inspiring colleagues, hearing about their research interests, and, hopefully, developing relationships for future collaborations."

READ DR. FLEMING'S FULL SPOTLIGHT HERE
 

MCDC Mentoring Lecture Series

The IDCRC Mentoring Lecture Series brings the IDCRC mentees together with leading experts to discuss topics related to the VTEUs, vaccinology, and clinical trials development and management. Check out our recent lecture below!

 

October Lecture: Time Management Techniques

Presenter:
Monica Gandhi, MD, MPH
Professor of Medicine, Associate Division Chief (clinical operations/education)
Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco

October Lecture: Time Management TechniquesOctober Lecture: Time Management Techniques
VIEW FULL ARCHIVE OF MENTORING LECTURES HERE
 

News

IDSA | "RSV Immunization in Infants Is Safe and Provides High Antibody Levels Regardless of Mother’s Vaccination Status"

Vaccination against RSV is recommended by the Centers for Disease Control and Prevention for people between 32-36 weeks pregnant, as well as immunization for all infants under eight months not otherwise protected through vaccination during pregnancy. While most infants do not need both products to provide protection through their first respiratory season, there are some clinical scenarios when infants may receive both. 

Child with RSV

This study is ongoing as researchers will follow up with participants to access immune durability for one year in mothers, infants and in breast milk. While the vaccine is proven to be safe and well tolerated in infants, researchers say durability of immunity for mothers and infants has yet to be fully described. The study is being conducted by the Infectious Diseases Clinical Research Consortium through funding from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health (UM1AI48684).

READ FULL ARTICLE
 

NYU Langone Health launches Transplant ID Fellowship Program

Photo of ID fellows with NYU Grossman School of Medicine logo

The NYU Langone Health team established a NEW Transplant Infectious Disease Fellowship Program. This one-year program will start on July 1, 2026, located at the NYU Langone Health/NYU Transplant Institute.

This program will provide fellows with specialized training in transplant infectious diseases, clinical and research opportunities, interdisciplinary collaboration, and much more!

 Eligibility:

  • Completion of an accredited infectious diseases fellowship
  • Board-certified in internal medicine and infectious diseases

​​​​​​Application: 
Are you interested in applying? Do you know someone who might be a good fit? If so, please send your CV and LORs to Lucy Maldonado by Monday, December 15!

 

Contemporary Pediatrics spotlights C. Buddy Creech, MD

Contemporary Pediatrics recently spotlighted a presentation C. Buddy Creech, MD, MPH (Vanderbilt), delivered at the American Academy of Pediatrics 2025 National Conference and Exhibition. In this video, Dr. Creech discusses emerging trends in vaccine research and development.

Buddy Creech AAP Presentation
READ FULL ARTICLE AND WATCH HIS PRESENTATION
 

NFID Infectious IDeas | Fact vs. Fiction: Top Vaccine Myths Debunked with Kathy Neuzil, MD, MPH

NFID Infectious IDeas

Myths about infectious diseases can spread just as quickly as the viruses themselves. In this special compilation episode of Infectious IDeas, experts revisit some of the most common myths and misconceptions busted by past guests. Tune in to this episode to hear from several thought leaders, including former IDCRC principal investigator Kathleen M. Neuzil, MD, MPH!

CLICK HERE TO LISTEN
 

Job Postings

Newly Posted! Infectious Diseases Research Job Openings

  • Northwestern Medicine - Infectious Diseases Clinician-Educator
  • Rush University Medical Center - Microbial, Pathogens & Immunity Research Faculty
  • The Ohio State University Wexner Medical Center - Post Doctoral Scholar - Microbial Infection & Immunity

  • University of Birmingham at Alabama (UAB) - Postdoctoral Position in Biochemistry and Electron Microscopy of Membrane Proteins 

Visit the IDSA Career Center to browse other ID/HIV Medicine job postings.

 

Funding Opportunities

2026 Deadline: 

Notice of Special Interest (NOSI): Complement in Fundamental Immunology 
Deadline:  Tuesday, January 7, 2026

Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine 
Deadline: Thursday, January 15, 2026

Georgia CTSA TL1 (T32-like) Clinical and Translational Research Training Program *NEW*
Deadline: Tuesday, February 17, 2026

Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives
Deadline: Friday, July 17, 2026

Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses  
Deadline: Friday, July 17, 2026

Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)  
Deadline: Friday, August 7, 2026

2027 Deadline:

Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) 
Deadline: Wednesday, April 6, 2027

Notice of Special Interest (NOSI): Systems Modeling of Infection and Immunity Across Biological Scales 
Deadline: Wednesday, September 8, 2027

Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Universal Influenza Vaccine 
Deadline: Sunday, November 17, 2027

Notice of Special Interest (NOSI): Accelerating Malaria Vaccine and Monoclonal Antibody Discovery 
Deadline: Sunday, November 17, 2027

 

IDCRC Studies

Active Studies Recruiting Volunteers

  • A Phase 4 Study of a 3-Day vs. 7-Day Regimen of Doxycycline for the Treatment of Chlamydial Infection (DMID 22-0019)

Fully Enrolled Studies in Follow-up

  • A Randomized, Double-Blind, Placebo-Controlled Phase 1 Trial to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of Sanaria(R) PfSPZ-LARC2 Vaccine, a Late-Arresting, Replication-Competent, Genetically Attenuated Plasmodium Falciparum Vaccine by Controlled Human Malaria Infection in Malaria-Naïve Healthy Adults Conditions (DMID 23-0010)
  • Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults (DMID 23-0006)
  • A Phase 1 Trial to Evaluate the Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine, HydroVax-001B WNV in Healthy Adults (DMID 24-0008)

  • Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine (DMID 22-0020A)

  • A Phase 1, Randomized, Placebo-Controlled, Double-Blind Study to Assess the Safety and Pharmacokinetics of a Single Ascending Dose of EV-D68-228 in Healthy Adult Volunteers (DMID 23-0005)

  • A Prospective, Randomized, Open-label Phase 4 Study of the Immunology and Safety of Maternal RSV Vaccination (ABRYSVOTM), Infant Nirsevimab (BEYFORTUSTM) Immunization, or Both Products During the First Year of Life (PROMISE) (DMID 24-0003)
IDCRC ACTIVE AND COMPLETED STUDIES
 

IDCRC Concept Quick Stats

ICP Status

  • Approved: 70

  • Administratively Not Supported: 29

  • Not Approved: 77

  • EWG Review: 2

  • EWG Liaisons: 0

  • EMT Concurrence: 0

  • Withdrawn: 23

  • Hold: 0

  • Moved to Active Study: 7

EWG Assignment

  • COVID: 92

  • Respiratory: 50

  • Emerging Infections: 22

  • Enteric Inf.: 12

  • Malaria and Tropical Dis.: 13

  • Sexually Transmitted Infections: 19

  • Mpox: 7

ECP Status

  • EWG Review-In Process: 0

  • EMT Review: 0

  • Approved-moved to Prioritization: 0

  • Not Approved: 29

  • Approved-moved to Protocol development: 2

  • Active Study: 7

  • EMT Vote: 1

  • Study in Protocol Development: 5

  • Study Closed (LSLV Complete): 9

  • Other: 11

IDCRC STUDIES
 

Communication Resources

COMMUNICATION TOOLKIT
 

Please submit IDCRC news to idcrc@emory.edu for inclusion in the monthly newsletter and IDCRC.org.

VISIT IDCRC WEBSITE
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SUBSCRIBE TO NEWSLETTER
 
 
 

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