The advent of genomic sequencing opened a new era of precision medicine in which treatments can take into account the unique differences between individuals. But there’s one major hurdle: The data is overwhelmingly from white people. As a result, researchers are unable to capture much of the genetic diversity of populations around the world. And lacking a full picture of all the forms the human genome can take can limit understanding of a given disease.

One global initiative is trying to change that. Researchers in 14 countries across four continents are collecting and analyzing DNA samples from around the world, trying to uncover the genetic underpinnings of mental illness. Hailiang Huang and his colleagues describe the guiding principles of the collaboration, and the new sequencing method they’ve developed to help capture the genetic diversity of humanity.

Ukrainian armed forces have made stunning progress in counteroffensives against Russia in the north-east and south, despite being significantly outgunned. As Russia and security expert Matthew Sussex explains, Russia’s ailing military performance raises the question of where Putin goes next. Escalation looks increasingly likely - but what form would that take?