The Conversation

Happy Sunday − and welcome to the best of The Conversation U.S. Here are a few of our recently published stories:

Every drug has an origin story – and just as developing a new drug brings new possibilities, uncovering how it was discovered can bring new responsibilities.

One “miracle drug” called rapamycin – now used to treat cancer and prevent organ transplant rejection, but which could also possibly address a host of conditions that include diabetes, neurodegenerative diseases and aging itself – was found in the soils of Easter Island in 1964. Most researchers studying this drug know that much.

But who, how and why was this discovery made in the first place? The answer to this question is complicated – and raises ethical quandaries for scientists and pharmaceutical companies.

Molecular biologist Ted Powers has spent decades studying how rapamycin affects cells. After taking a pilgrimage to Easter Island to see where his career came from, so to speak, he made a discovery of his own: a newfound obligation to share the story of the Indigenous people whose role as “living laboratories” in the initial expedition have largely been erased from the narrative.

“Omissions in the origin stories of rapamycin reflect common ethical blind spots in how scientific discoveries are remembered,” writes Powers, who is now working toward building a stronger relationship with the island and avenues for more equitable exchange.

He traces the biases and power imbalances that led to discovery of rapamycin – raising questions about what fair compensation and recognition from the scientific community and pharmaceutical industry should look like.

Vivian Lam

Associate Health and Biomedicine Editor

Readers' picks

A billion-dollar drug was found in Easter Island soil – what scientists and companies owe the Indigenous people they studied

Ted Powers, University of California, Davis

Cancer. Diabetes. Aging itself. Rapamycin’s potential to treat an array of diseases has been a source of scientific fascination. But many aren’t aware of its origins – and its complicated legacy.

‘Warrior ethos’ mistakes military might for true security − and ignores the wisdom of Eisenhower

Monica Duffy Toft, Tufts University

As hundreds of military brass descend on a base in Virginia to be addressed by Pete Hegseth, his newly bestowed title is ‘Secretary of War.’ That means something.

Tibetan Buddhist nuns are getting advanced degrees − and the Dalai Lama played a major role in that shift

Darcie Price-Wallace, Northwestern University

A 2012 change has seen scores of Tibetan Buddhist nuns achieve the highest degree in Tibetan Buddhist philosophy. The implications go beyond just higher learning.

Venezuela and US edge toward war footing − but domestic concerns, international risks may hold Washington back

Robert Muggah, Instituto Igarapé

US military buildup in the Caribbean has prompted Venezuelan President Nicolás Maduro to reciprocate with military drills.

A staircase in a small, decorative arts museum tells a harrowing story of terror, abuse and enslavement

Susanna Ashton, Clemson University; Mollie Barnes, University of South Carolina Beaufort

The staircase was originally acquired due to its craftsmanship. Only later did scholars realize that it was where Harriet Jacobs suffered abuse at the hands of her enslaver.

Editors' picks

Jane Goodall, the gentle disrupter whose research on chimpanzees redefined what it meant to be human

Mireya Mayor, Florida International University

Without formal scientific training, Goodall upended the study of animal behavior. She also inspired countless people to protect nature.

As an OB-GYN, I see firsthand how misleading statements on acetaminophen leave expectant parents confused, fearful and lacking in options

Tami S. Rowen, University of California, San Francisco

Fever during pregnancy presents real dangers to both the mother and the fetus – an OB-GYN explains the critical role of acetaminophen in preventing serious outcomes.

Violent acts in houses of worship are rare but deadly – here’s what the data shows

James Densley, Metropolitan State University ; Jillian Peterson, Hamline University

Tragedies like the Sept. 28, 2025, shooting at the Church of Jesus Christ of Latter-day Saints chapel in Michigan are part of a longer pattern.

Trump administration is on track to cut 1 in 3 EPA staffers by the end of 2025, slashing agency’s ability to keep pollution out of air and water

Elizabeth Blum, Troy University; Chris Sellers, Stony Brook University (The State University of New York)

Careful research into public information and in-depth interviews has shown the scale of personnel cuts at the Environmental Protection Agency.

Ending taxes on home sales would benefit the wealthiest households most – part of a larger pattern in Trump tax plans

Beverly Moran, Vanderbilt University

Most sellers already pay no tax, so the proposal’s benefits would flow to the richest.

News Quiz 🧠

  • The Conversation U.S. weekly news quiz

    Fritz Holznagel, The Conversation

    Test your knowledge with a weekly quiz drawn from some of our favorite stories. Questions this week on chimpanzees, facial hair and nuns.