On The Cutting Edge | July 2023

July 21, 2023

Click the image below to check out what our research residents are working on!

Please note the room change!

In Case You Missed It

Mentorship Database: The Division of Research is implementing initiatives to organize the process of matching research residents and medical students with faculty members for research opportunities. If you are a faculty member interested in mentoring a medical student and/or a resident, please fill out this Qualtrics survey: Survey
NIH Scientific Data Sharing Website: Whether you are involved in an NIH-funded project and want to understand which sharing policies apply to your research and how to comply, or you are a researcher looking to access scientific data from NIH-affiliated repositories, this site is for you. | More information
Grant Writing Club: Designed for anyone in the grant writing process, provides peer feedback on grants prior to or after to submission. Meets Tuesdays evenings at 5:30 PM, quarterly in the HUB6520/virtually. Participants should send a draft of their grant 1-2 weeks prior to the meeting for dissemination to peer reviewers. The club is highly interactive and participants are required to review and/or submit. Please email Rachel Morris , MD if you are interested in participating.
Department of Surgery Intranet Site: Cultural Complications/Grand Rounds/Quality Minute presentations, Surgery Sparks of Gratitude, Global Surgical Programs, Finance/Reimbursement links, DOS Phone list, and resources for logos/fonts/templates. | More Information
Abstract Deadlines and Meeting List: List will be updated each month | More Information

SurPASS Tip of the Month

Outgoing Subawards

When a DOS PI identifies a potential subrecipient institution outside MCW to participate in a research project, we refer to that as an “outgoing subaward”.

Outgoing subawards are reviewed by GCO as part of the main application in eBridge.

Subrecipient institutions need to provide the following items for an outgoing subaward:

Statement of Work (SOW)
Detailed Budget
Budget Justification
Letter of Intent
Biosketches for Senior/Key personnel
Letter of Support
Facilities and Other Resources
Equipment, if applicable

GCO will review the main application from the PI as well as the outgoing subaward all at the same time. When approved, all application documents can be submitted to the sponsor.

Any questions? Contact Lynn Cummings, Grants Operations Coordinator

Clinical Research Tip of the Month

OnCore Financials is LIVE Effective July 10

We are excited to announce that OnCore Financials is LIVE effective July 10! Thank you to the identified trainees and pilot builders in the department for their dedication to this important initiative.

F&MCW has committed to the implementation of OnCore Financials to standardize workflows and enhance the way clinical research is conducted across the organization. The MCW Office of Research (MCW OOR) is now requiring use of OnCore for all new studies that involve Froedtert Health Charges and/or MCW Professional Charges requiring Epic billing. For all other new studies, protocol entry into OnCore is strongly recommended per the OnCore protocol decision tree. Please refer to the OnCore Financials Toolbox for a multitude of resources to guide you through this new workflow.

To facilitate Financials implementation, MCW OOR is defining “New” protocols as those that have not yet initiated any pricing/budget components as of 7/10/23. Studies that have not initiated these activities are required to follow the new process via OnCore. Full guidance on how to manage studies at different phases of the start-up process can be found here.

Please contact Krissa Packard at kpackard@mcw.edu with any questions regarding use of OnCore.

GRANT$ Alert

NIH High-Risk, High-Reward Funding Opportunities
See link more info on each opportunity
Due dates in mid-August and early September 2023

This program supports projects with highly innovative research with the potential for broad impact. There are 4 opportunities currently open.

American Cancer Society - Clinical Research Professor Award
$80,000/year for 5 years
Letter of Intent due: August 1, 2023
GCO deadline: October 8, 2023
Application due: October 15, 2023

Grant for investigators who have the rank of full professor and made seminal contributions in the area of cancer control that have changed the direction of clinical, psychosocial, behavioral, health policy, or epidemiologic cancer research.

2024 Searle Scholars Program
$100,000/3 years
Nomination documents due: August 1, 2023
GCO deadline: September 22, 2023
Application due: September 29, 2023

First-time Assistant Professors appointed on or after May 1, 2022 are eligible to apply. Only 1 nominee allowed from MCW. Please contact Lynn Cummings before submitting nomination documents.

Elsa U. Pardee Foundation Grant
No limit on funding, up to 1 year
GCO deadline: August 24, 2023
Application due: August 31, 2023

The Foundation funds projects which will allow establishment of capabilities of new cancer researchers, or new cancer approaches by established cancer researchers. It is anticipated that this early stage funding by the Foundation may lead to subsequent and expanded support using government agency funding. Project relevance to cancer detection, treatment, or cure should be clearly identified.

AHW MCW-Led Seed Grants
$50,000 for 1 year
Share draft app with AHW: August 28, 2023
GCO deadline: N/A
Application due: September 11, 2023

For MCW faculty to develop new approaches and methodologies, test innovative ideas, and foster greater collaboration to address Wisconsin’s leading health challenges. Successful seed grants will build a foundation for future research and healthcare provider workforce development endeavors beyond the project period.

Mellowes Center Mini-Grants - Sequencing, Bioinformatics, and Analysis
18 hours of Mellowes Center bioinformatics analytics services
Up to 10 eligible projects will be funded annually

Small-scale research projects will receive 18 hours of Mellowes Center bioinformatics analytics services.

AHW MCW-Led Learning Event Support Funding
$5,000 per learning event
Application accepted until December 31, 2023 as long as funding remains available

Rolling first-come, first serve basis.

Herma Heart Institute Seed Money
$10,000 one-time request
Proposal due in eBridge: N/A
Application due: Reviewed quarterly

Must have an HHI faculty member as the PI or co-PI.

Abstracts Alert

Society of Critical Care Medicine (SCCM) Critical Care Congress
January 21-23, 2024 | Phoenix, AZ
Abstract deadline: August 2, 2023

Eligibility Requirements 
Abstracts, case reports, and/or data previously presented or published nationally or internationally are not allowed.
Abstracts and case reports presented at an SCCM chapter meeting are allowed.
Abstracts and case reports may contain new research on a topic presented previously.
Submission of an abstract or case report constitutes a commitment by the author(s) to present the abstract or case report as accepted.
Stimulating and unique abstracts or case reports will be considered for the 2024 Congress program.

2023 Pacific Northwest Vascular Society (PNWVS) Annual Meeting
November 2-3, 2023 | Vancouver, B.C.
Abstract deadline: August 14, 2023

More information can be found here: https://pacificnwvascular.org/annual-meeting-2/

The Association of Academic Surgery (AAS)/The Society of University Surgeons (SUS) Annual Academic Surgical Congress
February 6-8, 2024 | Washington, D.C.
Abstract deadline: August 18, 2023

Abstract Type: Basic science, Clinical/Outcomes, Education
Clinical Area: Breast, Cardiothoracic, Colorectal, Cross disciplinary, Endocrine, General surgery, Global surgery, Hepatopancreatobiliary, Minimally invasive surgery, Oncology, Pediatrics, Plastics, Transplantation, Trauma/Critical care, Upper GI/Bariatric, Vascular
Scientific Area: Basic Science/Translational - Cellular and molecular biology, Developmental Biology/Tissue engineering, Experimental therapeutics, Genetics, Immunology/Immunotherapy, Physiology/Pathophysiology, Precision Medicine/Biomarkers, Preclinical surgical innovations, Other
Clinical/Outcomes - Clinical trials, Clinical surgical innovations, Cost effectiveness, Disparities and access to care, Ethics/Bioethics, Geriatric surgery and palliative care, Health informatics, Health policy/Patient safety, Patient-centered outcomes, Qualitative research methods, Quality of care, Other
Education - Continuing medical education, Resident education, Simulation education, Other

Wisconsin Surgical Society (WSS) Annual Conference
November 3-4, 2023 | Kohler, WI
Abstract deadline: September 3, 2023

Surgeons, students, residents, advanced practice practitioners, nurses, and researchers are all welcome to submit abstracts related to basic science, clinical, and health services research; quality improvement projects; education, policy, and advocacy initiatives; interesting case reports; and any other surgery-related topic you wish to share.
You may submit more than one abstract, but only one will be accepted for presentation. You may be a co-author or senior author on an unlimited number of abstracts.
All abstracts must be sponsored by a WSS member.

Western Trauma Association (WTA) Annual Meeting
February 25-March 1, 2024 | Snowmass, CO
Abstract deadline: September 4, 2023

Abstract Blinding: Abstracts must be blinded, meaning any references to authors or institutions should be removed from the abstract title, content and attachments. You must ensure that your abstract is blinded and does not reveal anything about you or your institution. Abstracts that are not blinded will be disqualified.
Abstract Content: Please structure your abstract using the following headings: Introduction, Methods, Results, Conclusion.
Attachments: Only one attachment per abstract may be submitted. Files must be in .jpg format and legible and fit in the parameters of the above-mentioned template along with your abstract content.
Abstract Sponsor: All abstracts must have a WTA Member Sponsor.

Vascular and Endovascular Surgery Society (VESS) 2024 Annual Winter Meeting
January 18-21, 2024 | Sun Valley, ID
Abstract deadline: September 6, 2023

Submissions Categories: Standard papers, Rapid fire presentations, Case reports, Video case reports

Department of Surgery Recent Publications

Early Shared Decision-Making for Older Adults with Traumatic Brain Injury: Using Time-Limited Trials and Understanding Their Limitations. Neurocritical Care. (Miranda SP, Morris RS, Rabas M, Creutzfeldt CJ, Cooper Z)

Attributional negativity bias and acute stress disorder symptoms mediate the association between trauma history and future posttraumatic stress disorder. Journal of Traumatic Stress. (Webb EK, Timmer-Murillo SC, Huggins AA, Tomas CW, deRoon-Cassini TA, Larson CL)

The Variation of Withdrawal of Life Sustaining Therapy in Older Adults With Traumatic Brain Injury. Journal of Surgical Research. (Pokrzywa CJ, Al Tannir AH, Sparapani R, Rabas MS, Holena D, Murphy PB, Creutzfeldt CJ, Somberg L, Nattinger A, Morris RS)

Applications of Viscoelastic Testing in Breast Cancer Patients: A Systematic Review Focusing on Hypercoagulability and Free Flap Thrombosis. Seminars in Thrombosis & Hemostasis. (Pamulapati S, Conroy M, Madireddy S, Kamaraju S, Cortina C, Moore H, Hartmann J)

Surgical Management of Breast Amyloidosis. [Review]. Clinical Breast Cancer. (Bacos JT, Doren E, D'Souza A, Jorns J, Kong A)

Development and Evaluation of an Enhanced Recovery Protocol to Reduce Length of Stay Following Elective Endovascular Aneurysm Repair. Annals of Vascular Surgery. (Polovneff AO, Olowofela AS, Rossi PJ, Hart J, Malinowski MJ, Lewis BJ, Brown KR, Mansukhani NA)

Shattered Kidney After Renal Trauma: Should it be Classified as an American Association for the Surgery of Trauma (AAST) Grade V Injury? Urology. (Keihani S, Rogers D, Wang SS, Gross JA, Joyce RP, Hagedorn JC, Majercik S, Sensenig RL, Schwartz I, Erickson BA, Moses RA, Patrick Selph J, Norwood S, Smith BP, Dodgion CM, Mukherjee K, Breyer BN, Baradaran N, Myers JB)

Grade V renal trauma management: results from the multi-institutional genito-urinary trauma study. World Journal of Urology. (Hakam N, Keihani S, Shaw NM, Abbasi B, Jones CP, Rogers D, Wang SS, Gross JA, Joyce RP, Hagedorn JC, Selph JP, Sensenig RL, Moses RA, Dodgion CM, Gupta S, Mukherjee K, Majercik S, Smith BP, Broghammer JA, Schwartz I, Baradaran N, Zakaluzny SA, Erickson BA, Miller BD, Askari R, Carrick MM, Burks FN, Norwood S, Myers JB, Breyer BN)

Altered contractility, Ca2+ transients, and cell morphology seen in a patient-specific iPSC-CM model of Ebstein’s anomaly with left ventricular noncompaction. American Journal of Physiology - Heart & Circulatory Physiology. (Thareja SK, Anfinson M, Cavanaugh M, Kim MS, Lamberton P, Radandt J, Brown R, Liang HL, Stamm K, Afzal MZ, Strande J, Frommelt MA, Lough JW, Fitts RH, Mitchell ME, Tomita-Mitchell A)

Deep learning classification of deep ultraviolet fluorescence images toward intra-operative margin assessment in breast cancer. Frontiers in Oncology. (To T, Lu T, Jorns JM, Patton M, Schmidt TG, Yen T, Yu B, Ye DH)

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