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R&D News Roundup: August 15, 2022

 

Top News in R&D

New Langya virus that can affect people identified in eastern China
Nature (8/11)

Scientists in eastern China have identified an animal virus that has jumped to people, infecting 35 since 2018. Named the Langya henipavirus, it causes respiratory symptoms and is closely related to two other human henipaviruses, Hendra and Nipah. While scientists believe the virus is not fatal, nor does it seem to spread easily between humans, experts have urged ongoing surveillance and further research into the virus, especially as zoonotic disease outbreaks become more common worldwide. The virus is believed to be carried by wild shrews although it is unclear whether people are infected directly or indirectly by these animals.

Additional coverage in Scientific American (8/11), Popular Science (8/11), The Washington Post (8/10), and Time (8/10)

Vaccine targeting fast-spreading Omicron subvariants could be ready for Fall as Pfizer, BioNTech announce trials
Forbes (8/8)

Last week, Pfizer and BioNTech announced new trials will start later this month of their updated mRNA vaccine aimed at protecting against the B.A.4 and B.A.5 Omicron subvariants, which have spread quickly and demonstrated heightened ability to evade existing vaccine protection. If the vaccines receive regulatory approval, the companies expect to roll out the updated vaccines by October. The approval process should be quicker than normal as the US Food and Drug Administration (FDA) is not requiring updated clinical data for the B.A.4- and B.A.5-updated shots, instead basing their approval on clinical data from the companies’ Omicron B.A.1-focused vaccine trials, which have already been submitted.

Additional coverage in Financial Times (8/8) and Reuters (8/8)

US moves to stretch out monkeypox vaccine supply
The New York Times (8/8) and NBC News (8/9)

The Biden administration is stretching out its limited supply of Jynneos monkeypox vaccine to address the growing public health issue and supply shortage in the face of high demand for the vaccine. On Tuesday, August 9, the FDA issued an emergency use authorization to allow the method of injecting one-fifth of the normal dose amount into the skin rather than a full dose into the fat. The guidance still urges health care providers to continue to follow the regimen of two shots 28 days apart with the lower dose amount. The administration is recommending this method to ensure more high-risk people can access at least some vaccine protection.

Additional coverage in CNN (8/9), STAT (8/9), and CBS News (8/9)

 

 

News from GHTC

The climate crisis and infectious diseases: What role for DNDi?
Drugs for Neglected Diseases initiative blog (8/12)

New report credits WHO with reforms that accelerate access to health innovations, but finds “pain points” persist that slow product reviews
GHTC press release (8/10)
Additional coverage in Health Policy Watch (8/11)

Opinion: Localise global health to transform Africa’s healthcare systems
Mail & Guardian (8/10), by Speak Up Africa, features the Bill & Melinda Gates Foundation

Scripps Research scientists discover antibodies that induce broad immunity against SARS viruses, including emerging variants
Scripps Research press release (8/10), features research supported by IAVI and Gates Foundation

Monkeypox bill provides crucial steps toward equitable access to testing
Infectious Diseases Society of America statement (8/10)

Cellid, IVI to apply for Covid-19 vaccine trial in Kenya, Tanzania
Korean Biomedical Review (8/8), features International Vaccine Institute

Women play a key role in food and nutrition security in Nigeria
Africa.com (8/8), features HarvestPlus

 

 

Highlights From the Week

 

 

COVID-19 R&D spotlight

 

 

Monkeypox R&D spotlight

 

 

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