Top News in R&D





 Global Health Technologies Coalition 


R&D News Roundup: September 5, 2023


Top News in R&D

WHO secures first COVID-19 vaccine license from private pharmaceutical company
Health Policy Watch (8/31), features Medicines Patent Pool

The World Health Organization (WHO) last week announced its first COVID-19 vaccine license agreement through the COVID-19 Technology Access Pool (C-TAP) with Taiwanese manufacturer Medigen Vaccine Biologics Corp. The vaccine license was acquired through the Medicines Patent Pool, which also enabled last week additional agreements under C-TAP for a COVID-19 vaccine prototype and a test used to measure COVID-19 antibody levels. While C-TAP was launched at the height of the pandemic to promote technology sharing to improve access, particularly to vaccines, in low-income countries, major pharmaceutical companies have thus far declined to join the initiative.

Higher dose and shorter tuberculosis treatment proven safe for patients
MedicalXpress (8/29)

A clinical trial led by researchers at St George’s, University of London found that a higher dose of the antibiotic rifampicin for an abbreviated four-month treatment regimen for tuberculous (TB) was safe with no increases in side effects or toxicities, compared to the standard six months, which is WHO-recommended. The trial took place among adults with newly diagnosed pulmonary tuberculosis in Uganda, Guinea, Peru, Nepal, Botswana, and Pakistan. Experts say shorter treatment regimens will help lower costs and increase patient compliance, which will in turn reduce transmission and the development of resistance to available TB drugs.

$46.3 million award for more bird flu vaccines
Precision Vaccinations (8/28)

CSL Sequiris announced that it received an award from the Biomedical Advanced Research and Development Authority (BARDA) to deliver a vaccine for bird flu to the US government, increasing BARDA’s stockpile in case of an outbreak. The company will deliver one bulk lot of the H5N8 A/Astrakhan antigen to the US government, whose development has been supported by BARDA in recent years. The agreement is intended to improve US national vaccine preparedness and is especially significant as bird flu continues to be detected around the world, including a small number of human cases.



News from GHTC

CEPI and IVI renew partnership to accelerate development of vaccines against emerging infectious disease threats
Coalition for Epidemic Preparedness Innovations (CEPI) press release (9/1), features the International Vaccine Institute (IVI)

Gates Foundation awards multiple grants for Omics, Dx projects in August
360Dx (8/31), features the Bill & Melinda Gates Foundation

Researchers behind AstraZeneca's COVID shot reunite to prepare for future pathogens
Fierce Biotech (8/30), features CEPI

Global Fund secures deal to slash HIV treatment price
The East African (8/30), features the Gates Foundation

J&J, India's Lupin cut prices for tuberculosis drug in lower-income countries
Reuters (8/30), features Johnson & Johnson

Opinion: How do we solve a problem like tuberculosis?
Nature (8/30), features the Gates Foundation

Health Canada accepts Valneva’s Chikungunya vaccine license application for review
Valneva press release (8/29)

Day Zero Diagnostics wins $300K SBIR grant for fecal microbiota transplant assay
360Dx (8/29), features the Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X)



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