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R&D News Roundup: December 19, 2022

 

Top News in R&D

Medicines for Malaria Venture joins African manufacturing initiative
Health Policy Watch (12/15), features Medicines for Malaria Venture

Last week, Medicines for Malaria Venture and the Africa Centres for Disease Control and Prevention (CDC) signed a memorandum of understanding for providing technical support to African manufacturers for the development of antimalarial drugs. The support is aimed at helping improve the quality of antimalarial products to meet World Health Organization’s (WHO’s) standards in order to increase the use of locally produced drugs and make them eligible for bulk procurement by global institutions, as well as to address the high burden of malaria on the continent. This effort is also part of a wider initiative to increase African manufacturing after COVID-19 uncovered the risks of the continent’s over-reliance on imported drugs.

Aspen, CEPI and the Bill & Melinda Gates Foundation expand commitments to improve access to vaccines in Africa
CEPI press release (12/12), features CEPI and the Gates Foundation

The Bill & Melinda Gates Foundation and the Coalition for Epidemic Preparedness Innovations (CEPI) are investing US$30 million in Aspen Pharmacare Holdings Limited to support the manufacturing of routine and outbreak vaccines for Africa. Through a ten-year agreement with the Serum Institute of India, Aspen will use the investment to manufacture and distribute the routine Pneumococcal, Rotavirus, Polyvalent Meningococcal, and Hexavalent vaccines, as well as support technology-transfer activities and build regional vaccine manufacturing capacity for potential future outbreaks. The investment underlies a wider effort to ensure vaccine manufacturing capacity and supply of affordable vaccines on the continent.

As drug resistance surges, experts call for antibiotics for newborns to be prioritized
Health Policy Watch (12/12), features Global Antibiotic Research & Development Partnership

Joining a growing call for action in response to the increasing threat of antibiotic resistance, WHO recently published the Global antimicrobial resistance and use surveillance system (‎GLASS)‎ report: 2022, which identified a high level of antibiotic resistance in bacteria that can cause fatal bloodstream infections and an increasing level of resistance in bacteria that can cause common infections. The report echoes a wider concern about the need for the development of new antibiotics for newborn babies to address the up to 570,000 deaths and estimated three million cases of neonatal sepsis each year, many of which occur in the absence of effective antibiotics due to rising antimicrobial resistance.

 

 

Happy Holidays!

The R&D Roundup will be taking a break for the holidays and will be back in your inbox on January 3. 2023!

 

 

News from GHTC

COVID spurs boom in genome sequencing for infectious diseases
Nature (12/15), features FIND and the Bill & Melinda Gates Foundation

Ebola vaccine regimens safe, immunogenic in adults and children
US National Institutes of Health media advisory (12/14), features Johnson & Johnson

LumiraDx gets $14.2M in Gates Foundation grants to develop point-of-care molecular TB test
360Dx (12/14), features the Gates Foundation

Senegal joins CEPI in the fight against pandemics
CEPI press release (12/14)

Opinion: Even after COVID, the world’s vaccine strategy is failing
Nature (12/13), features CEPI and IAVI

Africa’s efforts to harmonize regulation of medicines are making progress
Health Policy Watch (12/13), features the Gates Foundation

An early lesson from the Uganda Ebola vaccine trial: Shots must be ready to go before the next outbreak strikes
STAT (12/13), features IAVI and Sabin Vaccine Institute

 

 

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