The leading theory on the cause of Alzheimer’s disease is that proteins called amyloid and tau accumulate and clump in the brain, causing it to malfunction. This leads to the well-known symptoms of memory loss, poor judgment, delusions and confusion. However, post-mortem studies of brains show that some older people die in apparent good health despite their brains containing enormous amounts of these toxic protein tangles.
Researchers recently found that genes related to the immune system are more active in people who are resilient to Alzheimer’s. Does that mean you need to be born with the right genes to be resilient to Alzheimer’s disease? Not necessarily, says Michael Hornberger, a professor of applied dementia research. You just need to boost your immune system through lifestyle changes.
A rare plant from my home country, South Africa, is in search of a partner. Encephalartos woodii, a cycad, has been around since the dinosaurs, but all remaining plants have been cloned from a single male plant. Scientists are desperately seeking Mrs woodii.
The UK Labour party became the latest to launch its election manifesto yesterday. Among plans to launch a public energy company, stop illegal migrant smuggling, ban energy drinks for under-16s and
reform the House of Lords, one policy that stood out for us at The Conversation was the plan to recruit 6,500 new teachers. Because research shows we’re struggling to hold on to the ones we’ve got.
In Wednesday’s newsletter, we incorrectly stated that Michael Mosley invented the 5:2 diet. As one of our readers reminded us, he merely popularised it.
Our spring donation campaign ends on Sunday. If you value our work scrutinising the pledges of politicians of all colours, then a donation of any size will make a real difference in these last few days.
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Clint Witchalls
Senior Health Editor
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Andrey_Popov/Shutterstock
Michael Hornberger, University of East Anglia
A special group of people appear to have genes that protect them from the worst effects of Alzheimer’s disease.
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Map from drone mission search for the Encephalartos Woodii in the Ngoye Forest in South Africa.
© C-LAB
Laura Cinti, University of Southampton
The plant has been propagated worldwide, but every surviving specimen of Encephalartos woodii is a male clone – and without a female, natural reproduction is impossible.
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Shutterstock
Joshua Fullard, Warwick Business School, University of Warwick
It could be argued that teachers who have remained committed to the profession are the ones who most deserve a reward, not new entrants.
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Politics + Society
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Stephen Clear, Bangor University
Keir Starmer’s manifesto stops short of the abolition Gordon Brown had wanted, but some immediate changes are confirmed.
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David Suber, UCL
Connections between smuggling and other forms of serious organised crime remain largely unverified.
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Rob McNeil, University of Oxford
Government policies can affect how many people arrive, what rights and protections they have in the UK, and what happens to those who arrive without permission.
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Business + Economy
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Jamie Speirs, University of Strathclyde
A nationally owned energy company could help the UK towards its net-zero goals but on its own the plan won’t be enough to provide long-term security.
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Mladen Adamovic, King's College London
The theories behind building a strong team performance.
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Environment
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Anupama Sen, University of Oxford; Sam Fankhauser, University of Oxford
Proposals are either poor (and eventually expensive) solutions, or suggest processes that are already in place.
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William Perry, Cardiff University; Simon Creer, Bangor University
Our research suggests environmental DNA analysis could transform traditional ways of monitoring freshwater ecosystems.
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Health
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Christina Vogel, City, University of London
People under the age of 18 should be banned from buying energy drinks. There is good evidence to support this measure.
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Claire Booth, UCL
Great Ormond Street Hospital plans to apply to the UK drugs regulator for a gene therapy to cure a rare genetic disorder called ADA-SCID.
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World
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Dan Feather, Liverpool John Moores University
Cyril Ramaphosa sees a Government of National Unity as the way ahead, but finding parties to agree to go ahead with this is challenging.
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Paul Rogers, University of Bradford
All indications are that Hamas is surviving the Israeli onslaught more successfully than previously anticipated.
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John Strawson, University of East London
Recent events in the Middle East reveal internal divisions in both the Israeli and Palestinian leaderships.
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Colin John Irwin, University of Liverpool
As with the Good Friday agreement in 1998, both sides in the Gaza war need to negotiate in good faith – but this is sorely lacking.
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Jonathan Este, The Conversation
A selection of our coverage of the conflict in Gaza from the past fortnight.
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Education
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Jeff King, UCL; David Mead, University of East Anglia
University leaders have struggled with how to respond to campus protests.
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Arts + Culture
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Alana James, University of Reading
Inside Out 2 shows that anxiety is a normal feeling and can have a positive purpose – so long as it doesn’t take over.
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Matthew Leggatt, University of Winchester
Arcadian manages to be both highly derivative and also quite unusual. It is part thriller, part creature feature and part horror.
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John Caro, University of Portsmouth
The Boys are back and this season there’s more blood, violence and contradictions
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Science + Technology
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Ava Green, City, University of London; Claire Hart, University of Southampton
Narcissistic women can be violent in relationships.
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Podcasts
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Gemma Ware, The Conversation
Astronomers Vicent Martínez and Bernard Jones explain the mystery of the Hubble tension, and why it matters so much for our understanding of the universe, on The Conversation Weekly podcast.
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19 April - 21 June 2024
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