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R&D News Roundup: December 4, 2023

 

Top News in R&D

BioNTech Rwanda vaccine manufacturing plant to be launched next month
The New Times (11/30)

This month, with support from the local government, German biotechnology company BioNtech is opening an mRNA vaccine factory in Rwanda, which is expected to become the first of what the company says will be a decentralized and robust end-to-end mRNA vaccine manufacturing network in Africa that will manufacture novel vaccines for Africans across the continent. The plant is expected to start by producing 50 million vaccines and will increase production based on demand. BioNTech is currently advancing vaccine candidates to address malaria and tuberculosis based on its mRNA vaccine platform.

South African company to start making vaginal rings that protect against HIV
Associated Press (11/29), features Population Council

Last week, Population Council announced that South African company Kiara Health will start producing vaginal rings for HIV prevention in the next few years, which could make the innovative tool cheaper and more readily available to women in Africa. The dapivirine ring, which has been authorized by nearly a dozen countries and the World Health Organization, offers women an alternative HIV prevention method that can be taken without anyone else’s knowledge or consent. Population Council owns the rights to the ring, which is currently produced by a Swedish company. About a half million rings have been made available freely in Africa through donor support. Population Council and Kiara estimate that the company will be able to produce double the currently available supply annually.

CEPI, IVI and MRC Unit The Gambia partner to bolster clinical research capacity in West Africa to combat regional viral threats
CEPI press release (11/28), features CEPI and IVI

The Coalition for Epidemic Preparedness Innovations (CEPI), the International Vaccine Institute (IVI), and Medical Research Council Unit The Gambia last week announced the launch of the Research Preparedness Program West Africa, which will support a consortium of regional stakeholders to bolster the growing clinical research sector across the region. Specifically, the partners will work toward building up clinical trial capacity to conduct the first-ever large-scale phase 2b and 3 clinical trials of Lassa fever vaccines in the region. The program also aims to improve general preparedness to ensure the capacity to generate high-quality clinical trial data during future outbreaks of other diseases in the region in as little as 100 days.

 

 

News from GHTC

HIV vaccine: Scientific advances spark cautious optimism
Vaccines Today (12/1), features IAVI and AVAC

Africa: As the world watches, Africa rises to face the infectious disease epidemic
All Africa (11/30), features the Drugs for Neglected Diseases initiative and the Global Antibiotic Research & Development Partnership

Will AI crack the code for antigens?
IAVI Report (11/30), features CEPI

These volunteers want to be infected with disease to aid research — will their altruism help?
Nature (11/28), features 1Day Sooner

Opinion: Bending the curve: What a decade-long roll-out of the anti-HIV pill can teach the world
Bhekisisa (11/28), written by AVAC

Report provides insight into USAID health R&D programs; shows increase in funding and projects supported but remaining needs
GHTC's Breakthroughs Blog (11/28)

 

 

Highlights From the Week

As dengue expands beyond the global 'dengue belt,' scientists dispel conventional wisdom about the disease
MedicalXpress (12/1)

Lab stakeholders question if FDA has resources to implement LDT oversight plans
360Dx (11/30)

Could CRISPR cure HIV someday?
Live Science (11/30)

A protein inhibited by GSK's Rukobia could be culprit behind HIV comorbidities, study suggests
Fierce Biotech (11/30)

These 10 lifesaving medical products are contributing to climate change
Devex (11/29)

Sequencing implicates older H5N1 avian flu clade in Cambodia's latest case and death
CIDRAP (11/29)

Anthrax outbreak: Kyotera death toll now rises to 17
Monitor (11/29)

Researchers develop a new early alert model for pandemic predictions in Germany
NewsMedical (11/29)

African civil society groups launch new alliance to combat pandemics and climate change
Health Policy Watch (11/29)

Africa Epidemics Fund slated for approval in February
Devex (11/29)

UK Biobank releases half a million whole-genome sequences for biomedical research
Science (11/29)

Denver Health medical team receives Ebola vaccine
News9 (11/28)

After Cyfendus' full approval, Emergent clinches $75M anthrax vaccine supply pact in US
Fierce Pharma (11/28)

Science advisory project eyes better pandemic response
SciDevNet (11/28)

Progressions in HIV research compromised by COVID-19 pandemic
Pharmacy Times (11/27)

UK detects its first human case of swine flu strain
The Guardian (11/27)

Mpox hits DR Congo hard as officials note sexual spread, 581 deaths
CIDRAP (11/27)

 

 

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