On The Cutting Edge | June 2025

June 20, 2025

In Case You Missed It

Faculty Mentorship/Student Help: The Division of Research has an established process for matching research residents and medical students with faculty members for research opportunities. These opportunities are to be strictly for volunteer work done by the student. Specifics on task work is completely up to the faculty member’s discretion. If you are interested in mentoring, please fill out this Qualtrics survey.
NIH Scientific Data Sharing Website: Whether you are involved in an NIH-funded project and want to understand which sharing policies apply to your research and how to comply, or you are a researcher looking to access scientific data from NIH-affiliated repositories, this site is for you. | More information
Department of Surgery Intranet Site: Funding Opportunities, Cultural Complications/Grand Rounds/Quality Minute presentations, Surgery Sparks of Gratitude, Global Surgical Programs, Finance/Reimbursement links, DOS Phone list, and resources for logos/fonts/templates. | More Information
Abstract Deadlines and Meeting List: List is updated weekly.| More Information

Upcoming Events

HRPP Professionals Meetings
- Tuesday, June 24 | OnCore Clinical Trials & Financials
- Tuesday, July 29 | Luau with the HRPP
- Tuesday, August 26 | The CRDW and CBMI Services
- Tuesday, September 30 | Custom Devices, Compassionate Use, & HDE/HUDs
- Tuesday, October 28 | QA/QI, Case Reports and NHSR Projects
- Tuesday, December 2 | TBD
CTSI Bootcamp: Clinical Research Basics
- Day 1: August 6, 2025; Day 2: August 19, 2025

Staff Feature

SurPASS Tip of the Month

Extension of Early Stage Investigator Status (ESI)

The NIH has released information about an extension of ESI eligibility for the following investigators (NOT-OD-25-114):

Investigators whose last submission date for a new/resubmission application, based on ESI eligibility, was October/November 2024 will be granted a three-receipt cycle extension (roughly twelve additional months). The last submission as an ESI will be October 2025
Individuals whose last submission date for a new/resubmission application, based on ESI eligibility, was February/March 2025 will be granted a two-receipt cycle extension (roughly eight additional months). The last submission as an ESI will be October 2025
Individuals whose last submission date for a new/resubmission application, based on ESI eligibility, will be June/July 2025 will be granted a one-receipt cycle extension (roughly four additional months). The last submission as an ESI will be October 2025

**Please reach out to Lynn Cummings, Grants Operations Coordinator, for assistance!**

Clinical Research Tip of the Month

Standardized Justification Documents for Budget Negotiations

Did you know MCW provides standardized clinical trial fee justification documents to streamline budget negotiations with industry sponsors? These documents, found on the OnCore Financials Budget webpage (OnCore Financials Budget), offer official MCW pricing language for key study start-up costs, including IRB fees, F&A, OnCore, Florence eReg, and more.

Using the current justification documents helps ensure consistency and reduces back-and-forth with sponsors, who are more likely to accept administrative costs when presented with standardized institutional language. These documents also save time for study teams by providing ready-to-use, institutionally approved language, helping avoid delays that can occur when starting from scratch or using outdated justifications.

Tip: Download a fresh copy for each use to ensure you’re working with the most up-to-date version.

Questions? Contact the OnCore Financials team for guidance or additional support.

GRANT$ Alert

DOD Rare Cancers Research Program (RCRP)
Preproposal due: July 1 or July 22, 2025
GCO deadline: August 19 or September 29, 2025
Application due: August 26 or October 6, 2025

Idea Development Award (IDA) and Resource and Community Development Award (RCDA) Preproposal due 7/1 and application due 10/6. Concept Award (CA) Preproposal due 7/22 and application due 8/26/25.

PCORI Broad Pragmatic Studies Supplemental Funding
GCO deadline: August 26, 2025
Application due: September 3, 2025

Cycle 2 2025 - no LOI required

NIH Director's New Innovator Award Program (DP2)
$475,000/year over 5 years
GCO deadline: August 12, 2025
Application due: August 19, 2025

PI must be an Early Stage Investigator, as identified in their eRA Commons profile. Proposals must be highly innovative with the potential for unusually high impact; preliminary data not required. Awardees are given unusual flexibility to pivot research direction as they see fit to maximize research impact.

NIH Director's Pioneer Award Program (DP1)
$700,000/year over 5 years
GCO deadline: September 2, 2025
Application due: September 9, 2025

Preliminary data and detailed experimental plans are not requested. This program requires proposed research that is substantially different from those being pursued by the PI's current research program. Awardees are required to commit 51% effort in the first 3 years, reduced down to 33% in year 4 and 25% in year 5.

American College of Surgeons 2026-2028 Faculty Research Fellowship
$40,000/year for 2 years
GCO deadline: 5 business days prior to app due
Application due: September 2025, date TBD

New for 2025: Franklin H Martin Award and C. James Carrico Award for Trauma and Critical Care. For Fellows or Associate Fellows who have completed chief residency year or fellowship training within the preceding 5 years and have a faculty appointment. Minimum 50% effort toward research project.

Robert Wood Johnson Foundation
Budget commensurate with project
3 year award period
Rolling deadline - submit LOI then invited to submit full proposal

Evidence for Action - research to advance racial equity; Pioneering Ideas - build a culture of health

Abstracts Alert

Southern Surgical Association (SSA) Annual Meeting
December 7-10, 2025 | Hot Springs, VA
Abstract deadline: June 30, 2025

More information can be found on the annual meeting page

Eastern Association for the Surgery of Trauma (EAST) Annual Scientific Assembly
January 20-23, 2026 | Atlanta, GA
Abstract deadline: July 1, 2025

Abstract categories: Basic Science, Clinical Science, and Injury Prevention*

International Surgical Week
April 19-23, 2026 | Mexico City, Mexico
Abstract deadline: August 8, 2025

Categories: General Topics; Digestive Surgery; Endocrine Surgery; Trauma & Intensive Care; Breast Surgery; Nutrition & Metabolism

Pacific Northwest Vascular Society (PNWVS) Annual Meeting
October 23-24, 2025 | Seattle, WA
Abstract deadline: August 11, 2025

More information can be found on the annual meeting page

Department of Surgery Recent Publications

A Piece of the Puzzle: Individualized Discharge Instructions for Firearm Injury Survivors. Journal of Surgical Research. (Prom JL, Manyitabot S, Laszkiewicz R, Cronn S, Schroeder ME)

Posttraumatic stress disorder mitigation in trauma patients: An evidence-based systematic review from the Eastern Association for the Surgery of Trauma. The Journal of Trauma and Acute Care Surgery. (Kartiko S, Atahar J, Rattan R, Zebley JA, Tatebe LC, Perea L, Ruggiero KJ, Levett P, Wassertzug D, Koenig S, Mashbari H, Smith RN, Hink AB, Allee L, Ortiz D, Hai SA, Butler C, Prince H, Murphy P, Teichman AL)

Hemolysis in Extracorporeal Membrane Oxygenation: A Comparative Analysis of Venovenous Versus Venopulmonary Arterial Approaches. ASAIO Journal. (Ramamurthi A, Derenne W, Donato B, Rein L, Butak W, Caswell C, Seadler BD, Alimi M, Ubert AH, Durham LA)

Breast Cancer Outcomes in Transgender and Gender-Diverse Patients in the National Cancer Database. JAMA Oncology. (Chan K, Cotler JH, Istl AC, Kamaraju S, Petroll AE, Stolley M, Cortina CS)

2024 Update to SAGES guidelines for the use of peroral endoscopic myotomy (POEM) in the treatment of achalasia. Surgical Endoscopy. (Calabrese EC, Kindel T, Slater BJ, Marks J, Swanstrom L, Saxena P, Docimo S, Athanasiadis DI, Hanna NM, Stefanidis D, Rooker C, Maddern G, Kohn GP)

Contemporary Biology, Management, and Outcomes of Renal Medullary Carcinoma in Children and Adults: A Pediatric Surgical Oncology Research Collaborative Study. Pediatric Blood & Cancer. (Beckhorn CB, Malek MM, Lovvorn HN, Leraas HJ, McKay KG, Kontchou NT, Kastenberg ZJ, Hoyt DW, Roach JP, Myers EK, Cost NG, Mullapudi B, Marchese CR, Jensen AR, Lautz TB, Carter M, Dasgupta R, Lundstedt J, Brungardt JG, Talbot LJ, Davidoff AM, Murphy AJ, Aldrink JH, Mansfield SA, Piche N, Lal DR, Craig BT, Schuh JM, Cromeens BP, Mannava SV, Castle SL, Lopez A, Mello K, Short J, Petroze RT, Rajaval S, Thompson GR, Mattei P, Rothstein DH, Fialkowski E, Fowler KL, Martchenke N, Rich BS, Glick RD, Brown EG, Doyle K, Abril P, Rinehardt HN, Seemann NM, Davidson J, Wilson CA, Le HD, Joshi D, Stellon M, Ahmed T, Dimmer AM, Newman EA, Hammoud M, Williams K, Grant CN, Gorgy M, Polites SF, Debertin J, Cameron DB, Stetson A, Kim ES, Lee WG, Barkhordar A, Austin MT, Coakley BA, Kahan A, Murphy JT, Pitonak M, Boehmer C, Tracy ET)

The intersection between firearm injury prevention and surgical practice: A qualitative study. The Journal of Trauma and Acute Care Surgery. (Waddle SD, Reyes AM, Thomas A, Betz ME, Johnson JK, Royan R, Ellyin A, Jang A, Crandall M, Stey AM, Campbell BT)

Improving Perioperative Mortality Rate Data Capture in Hawassa, Ethiopia: A Mixed-Methods Study. World Journal of Surgery. (Basmayor AMF, Fissehatsion J, Woisha B, Ergete AM, Sgro MV, Cook K, Ogunneye Q, Mellese B, Jaraczewski TJ, Dodgion C, Michael A, Beyene A, Iverson KR)

KRAS inhibition reverses chemotherapy resistance promoted by therapy-induced senescence-like in pancreatic ductal adenocarcinoma. Translational Oncology. (Abuelafia AM, Santofimia-Castano P, Estaras M, Grasso D, Chuluyan E, Lomberk G, Urrutia R, Dusetti N, Fraunhoffer N, Iovanna J)

Reutericyclin mitigates risperidone-induced suppression of anaerobic energy expenditure. American Journal of Physiology - Regulatory Integrative & Comparative Physiology. (Hadiono MA, Kazen AB, Aboulalazm FA, Burnett CML, Reho JJ, Kindel TL, Grobe JL, Kirby JR)

Damage control thoracotomy trends, techniques, and outcomes: An EAST multicenter trial. The Journal of Trauma and Acute Care Surgery. (Douglas AD, Puzio T, Murphy P, Nahmias J, Bugaev N, Kaafarani H, Tatebe L, Robinson B, Carrick M, Finch J, Smith H, Hoefer L, Keskey R, Snyder A, LeClair MJ, Turay D, Wang G, Capron G, Cheung D, Valgardsson A, Bankhead B, Liveris A, Taylor J, Cromer D, Goldenberg-Sandau A, Powers T, Ratnasekera A, Seng S, Figueroa J, Mulita F, Panagiotopoulos GI, Ramos J, Villalobos L, Frederick N, Favors L, Maxwell R, Spalding C, Kurian A, Sperwer K, Senekijan L, Gebran A, Burke R, Dalavayi S, Hoshal G, Cocanour C, Chang G, Meagher A)

Surgical Health Services Research as a Path to Health System Leadership. Annals of Surgery. (Broman KK, Greenup R, Dossett LA, Ghaferi A)

Primary repair versus resection for American Association for the Surgery of Trauma grades I and II colon injuries: Does the management approach really matter? An Eastern Association for the Surgery of Trauma multicenter trial. The Journal of Trauma and Acute Care Surgery. (Fitzgerald CA, Barnes C, Bisgaard EK, McLafferty BJ, Harrell KN, Fleming MM, Meizoso JP, Walker J, Sciarretta JD, Succar BE, Cheng M, Lewis RH Jr, Davis GR, Puli O, Egodage T, Mooney J, Nguyen S, Kirsch JM, Jose AM, Lumbard D, Finn A, Sheppard K, Shively KS, Butts C, Lasinski AM, Beattie NG, Noory MN, Chaudhary SA, Irish W, Leung P, Luketic K, Noorbakhsh M, Almahmoud K, Cash A, Bernard AC, Kumar A, DeSantis AJ, Kozar RA, Prasad A, Siletz AE, Schroeppel TJ, Rodriquez J, Tackett N, Mentzer C, Sabu-Kurian A, Bankhead BK, Bhattacharya B, Maung AA, Chang G, Ramoutar U, Farrell MS, Hamdan M, Wong YM, Deci RT, Fernandez L, Pero B, Palacio CH, Rendon Garcia JJ, Myall JJ, Riggle AJ, Golestani S, Dilday J, Miller A, Taveras L, Grande P, Scott S, Dumas RP)

Using Intraoperative Trauma Video Review to Assess Emergency Department to Operating Room Handoffs in Surgical Trauma Cases. Journal of Surgical Research. (Butak W, Caswell C, Gellings J, Wilson D, Tatakis A, Vala R, Farah A, Jankowski C, Milia D, Holena D)

Systematic review and meta-analysis of efficacy of helmet use and helmet laws to reduce mortality and cervical spine injury in adult motorcycle riders: A practice management guideline from the Eastern Association for the Surgery of Trauma. The Journal of Trauma and Acute Care Surgery. (Ratnasekera AM, Seng SS, Gardiner SK, Butler C, Goldenberg-Sandau A, Lu N, Abdel Aziz H, Appelbaum RD, Mashbari H, Hafiz S, Chowdhury S, Soe-Lin H, Reynolds JM, Teichman AL, Kartiko S, Kaufman EJ, Murphy P, Kodadek L, Rattan R)

National trends in neoadjuvant systemic therapy utilization in patients with early-stage HER2-positive breast cancer from 2016-2021: The impact of the KATHERINE trial. Breast Cancer Research & Treatment. (Cohen LN, Rogers CC, Lloren JIC, Kamaraju S, Chaudhary LN, Huang CC, Cobb AN, Singh P, Kong AL, Teshome M, Cortina CS)

Essential Knowledge and Skills for the Practice of Pediatric Surgical Oncology: A Modified Delphi Consensus Study by the APSA Cancer Committee. Annals of Surgical Oncology. (Tracy ET, Engwall A, Brown EG, Sun RC, Walther A, Beckhorn CB, Lal D, Rothstein DH, Roach J, Cost N, Rich BS, Ehrlich PF, Aldrink JH, Rodeberg D)

Trauma in pregnancy: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma. The Journal of Trauma and Acute Care Surgery. (Appelbaum RD, Yorkgitis B, Rosen J, Butts CA, To J, Knight AW, Zhang J, Kirsch JM, Levin JH, Riera KM, Kelley KM, Carter KT, Sawhney JS, Mukherjee K, Metz TD, Fiorentino MN, Cantrell S, Sapp A, Potgieter CJ, Kasotakis G, Como JJ, Freeman J)

Sentinel Node Biopsy Utilization in Wisconsin Women Undergoing Breast-Conserving Surgery for DCIS. Annals of Surgical Oncology. (Cortina CS, Schumacher JR, Cartmill RS, Venkatesh M, Lawson EH, Kong AL, Lautner MA)

An Educational Video Game in Trauma Triage at Nontrauma Centers: A Secondary Analysis of a Randomized Clinical Trial. JAMA Network Open. (Mohan D, Fischhoff B, Talisa V, Elmer J, White DB, Angus DC, Peitzman A, Bendesky B, Chapman AC, Forsythe RM, Guyette FX, Hynes AM, Oskvarek JJ, Weingart SD, Weinstock M,Chang CH)

Comparative survival of sleeve gastrectomy versus Roux-en-Y gastric bypass in adults with obesity: a systematic review and meta-analysis. Surgery for Obesity & Related Diseases. (Sakurai Y, Balakrishnan P, Kuno T, Yokoyama Y, Bowles M, Takagi H, Denning DA, Nease DB, Kindel TL, Munie S)

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