Division of Research - On the Cutting Edge Newsletter

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January 24, 2025

Award Announcements

Congratulations!

 
 

Applied Proteogenomics and OrganizationaL Learning and Outcomes (APOLLO)/Veterans Affairs Biobanking Initiative Program (VABIO)

Zablocki VA Medical Center - selected site

Timothy Ridolfi, MD, MS
Associate Professor
Division of Colorectal Surgery

 

2025 AHW MCW-Led Seed Grant awards 

Pharmacogenomic Mediators of Immunotherapy Resistance and Toxicity

Callisia Clarke, MD, MS
Chief, Associate Professor
Division of Surgical Oncology

Epigenetic Alterations Initiated by Gender-Affirming Testosterone in Breast Tissue

Angela Mathison, PhD
Assistant Professor
Division of Research

Cell-free DNA analytical validation supporting small blood volume test for infants and neonates

Michael Mitchell, MD
Chief, Professor
Division of Congenital Heart Surgery 

 

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In Case You Missed It

  • Faculty Mentorship/Student Help: The Division of Research is implementing initiatives to organize the process of matching research residents and medical students with faculty members for research opportunities. These opportunities are to be strictly for volunteer work done by the student. Specifics on task work is completely up to the faculty member’s discretion. If you are interested in mentoring, please fill out this Qualtrics survey.
  • NIH Scientific Data Sharing Website: Whether you are involved in an NIH-funded project and want to understand which sharing policies apply to your research and how to comply, or you are a researcher looking to access scientific data from NIH-affiliated repositories, this site is for you. | More information
  • Department of Surgery Intranet Site: Funding Opportunities, Cultural Complications/Grand Rounds/Quality Minute presentations, Surgery Sparks of Gratitude, Global Surgical Programs, Finance/Reimbursement links, DOS Phone list, and resources for logos/fonts/templates. | More Information
  • Abstract Deadlines and Meeting List: List will be updated each week.| More Information
 

Upcoming Events

  • CTSI Bootcamp - Clinical Research Basics
    • Day 1 - Self Guided, Day 2 - February 26, 2025
  • CTSI Research Coordinator Enrichment Series
    • Study Closeout Logistics | February 27, 2025 
 
 
 
SurPASS logo
 

SurPASS Tip of the Month

Keep your eRA Commons “Personal Profile” Updated

The Personal Profile module in eRA Commons is where you - as a principal investigator, award recipient, trainee, reviewer or other Commons user - tell NIH and other awarding agencies about yourself. Awarding agencies need to know about you to grant awards, process those awards and more. Here are a few reasons that it is extremely important to keep your Personal Profile updated.

  • Early Stage Investigator (ESI) status is calculated from Personal Profile data entered by principal investigators in the Education section.
  • Personal Profile data is used to help agency review staff identify reviewers’ conflict of interest with applications they are reviewing; and is the place reviewers enter information to get their review meeting honorariums.
  • All communications between awarding agencies and you are sent to contact methods that you enter into your Personal Profile.
  • Reports, such as the Research Performance Progress Report (RPPR), cannot be submitted if award recipients have incomplete Personal Profiles.
  • Trainees cannot be appointed without complete Personal Profiles.

Personal Profile is the central repository of information about all Commons registered users. It lets you own and maintain the accuracy for your own personal information. This profile information is integrated throughout eRA systems. It is used to determine reviewer conflicts, link publications, populate application data, track trainee effort, and to ensure that Early Stage Investigator status is accurately calculated. In addition, you have the option to provide demographic information to help NIH better understand its research workforce. Read more about how to manage your Personal Profile.

Linking your ORCID iD (Open Researcher and Contributor ID) to your eRA Commons account enables automatic importation of publications into biosketches, reducing burden and saving you time. You can use Personal Profile to connect your eRA Commons account to your ORCID iD (Open Researcher and Contributor ID), which is a unique 16-digit identifier that enables connections between researchers and their research and scholarship. A linked ORCID iD is required for all senior/key personnel listed on an application for a due date on or after May 25, 2025. See the video titled Link Your ORCID iD to Your eRA Commons Account.

If you have not recently updated your Personal Profile, please do so soon!

Reach out to Lynn Cummings, Grants Operations Coordinator, with any questions.

Clinical Research Tip of the Month

Routine Reviews of IRB-Approved Projects

Q: Did you receive a request for a routine review of your study?
Routine Reviews are a mechanism of the MCW Human Research Protections Program (HRPP) to verify the conduct of human research projects. These reviews are scheduled and conducted by the HRPP Quality Improvement staff.

Q: What is the purpose of a Routine Review?
Routine Reviews serve multiple important purposes:

  • Provide feedback to the PI and research team regarding the conduct of the research in accordance with the approved protocol, MCW policies/SOPs, federal regulations, and good clinical practices.
  • Offer an opportunity for the PI and study team to address questions or concerns about the research.
  • Support the HRPP mission to protect the rights, welfare, and privacy of human research participants by ensuring safety, regulatory compliance, scientific quality, and ethical standards are met.
     
    Additional Details

    Q: How are studies selected for Routine Review?
    Studies are randomly selected from eBridge. Each division will have four projects reviewed annually:

    • 2 Full IRB projects
    • 1 Expedited Review project
    • 1 Flex Review project

    Annual Review Schedule by Division

    • Surgical Oncology: Jan 15 – Feb 14
    • Colorectal Surgery: Mar 22 – Apr 20
    • Minimally Invasive and Gastrointestinal Surgery (MIGS): Mar 22 – Apr 20
    • Vascular Surgery: Jun 8 – Jul 7
    • Transplant Surgery: Aug 8 – Sep 6
    • Cardiothoracic Surgery: Aug 22 – Sep 20
    • Trauma & Acute Care Surgery: Oct 8 – Nov 6

    Q: What if the selected study has already been published and the project can be closed?
    If your study results have been published and the project can be closed, inform the HRPP QAQI review team. In most cases, they will not review your project.

    Q: How can I prepare for a Routine Review?
    Here are a few tips to ensure readiness:

    1. Verify that the study team members listed in eBridge are accurate and all have up-to-date CITI training.
    2. Review the collected data to confirm alignment with the approved study plan, including the time period and variables.
    3. If applicable to your study, check consent forms for completeness.

    Please contact Krissa Packard with any questions.

     

    GRANT$ Alert

    Damon Runyon Clinical Investigator Award
    $600,000 over 3 years
    GCO deadline: January 27, 2025
    Application due: February 3, 2025

    Requires 80% protected time conducting research.

    MCW Cancer Center Internal Funding
    $150,000/year over 2 years
    Letter of Intent due: February 15, 2025
    Application due: April 1, 2025
    no GCO

    Team Science Award

    MCW Cancer Center Internal Funding
    $40,000/year for 1 year
    Letter of Intent due: February 15, 2025
    Application due: April 1, 2025
    no GCO

    American Cancer Society - MCW Cancer Center Institutional Research Grant (ACS-IRG)

    MCW Cancer Center Internal Funding
    $150,000/year over 2 years
    Letter of Intent due: February 15, 2025
    Application due: April 15, 2025
    no GCO

    Clinical Trial Concept Award 

    Cardiovascular Center Keelan Research Foundation Award
    $75,000 for 1 year
    Application due: March 18, 2025

    Eligibility is for an Assistant Professor without current R01-equivalent funding.

    Cardiovascular Center Sally Bentley ESI Pilot Award
    $20,000 for 1 year
    Application due: March 18, 2025

    Eligibility is for an Assistant Professor without current R01-equivalent funding to acquire preliminary data, early stage ideas, and/or answer important research questions related to cardiovascular health or disease.

    Robert Wood Johnson Foundation
    Budget commensurate with project
    3 year award period
    Rolling deadline - submit LOI then invited to submit full proposal

    Evidence for Action - research to advance racial equity; Pioneering Ideas - build a culture of health

     

    Abstracts Alert

    The Endocrine Society ENDO 2025
    July 12-15, 2025 | San Francisco, CA
    Abstract deadline: January 30, 2025

     Topical Areas for Scientific Abstracts and Clinical Trials

    The American Association for the Surgery of Trauma (AAST) Annual Meeting
    September 10-13, 2025 | Boston, MA
    Abstract deadline: February 15, 2025

    Abstract Submission Guidelines

    World Transplant Congress (WTC) 2025
    August 2-6, 2025 | San Francisco, CA
    Abstract deadline: February 19, 2025

    Abstract Categories: Administrative; Basic Science; Vascularized Composite Allografts; Public Policy; Psychosocial & Ethics; Infectious Disease; Pharmacy; Kidney; Liver; Heart; Lung; Pancreas; Intestine; Organ Inclusive; Advanced Practice Provider

    American Society for Radiation Oncology (ASTRO) Annual Meeting
    September 27-October 1, 2025 | San Francisco, CA
    Abstract deadline: February 25, 2025

    Abstract Categories: Breast Cancer; Central Nervous System; Digital Health Innovation and Informatics; Diversity, Equity and Inclusion in Health Care; Gastrointestinal Cancer; Genitourinary Cancer; Gynecological Cancer; Head and Neck Cancer; Health Services Research/Global Oncology; Hematologic Malignancies; International/Global Oncology; Lunch Cancer/Thoracic Malignancies; Nonmalignant Disease; Nursing and Supportive Care; Palliative Care; Patient Reported Outcomes/QoL/Survivorship; Patient Safety; Pediatric Cancer; Professional Development/Medical Education; Biology - Radiation and Cancer Biology; Physics - Radiation and Cancer Physics; Sarcoma and Cutaneous Tumors

    American College of Surgeons (ACS) Clinical Congress 2025
    October 4-7, 2025 | Chicago, IL
    Abstract deadline: March 3, 2025

    Submission Categories: Bariatric/Foregut; Breast; Cardiac Surgery; Colon and Rectal Surgery; Endocrine; Ethics; General Surgery; Geriatric/Palliative Care; Global Surgery & Humanitarian Outreach; Health Services Research; Hepatobiliary and Pancreas; Military; Neurosurgery; Obstetrics and Gynecology; Ophthalmic Surgery; Orthopaedic Surgery; Otolaryngology; Pediatric Surgery; Plastic & Maxillofacial Surgery; Surgical Education; Surgical Oncology; Thoracic Surgery; Transplantation & Tissue Engineering; Trauma/Burn/Critical Care; Urological Surgery; Vascular Surgery

     
     

    Department of Surgery Recent Publications

    Bedside mental health risk screening of traumatic injury patients is enhanced by measurement of injury mechanism and social support. Injury. (Brier ZMF, Ruggiero KJ, deRoon-Cassini TA, Espeleta HC)

    Management of pleural effusion in mechanically ventilated critically ill patients: A systematic review and guideline. American Journal of Surgery. (Chiu WC, Bugaev N, Mukherjee K, Como JJ, Kasotakis G, Morris RS, Downton KD, Ho VP, Towe CW, Capella JM, Robinson BRH)

    Characterizing patterns of opioid prescribing after outpatient ventral hernia repair with mesh. Hernia. (Woo KP, Zheng X, Goel AP, Higgins RM, Iacco AA, Harris TS, Warren JA, Reinhorn M, Petro CC)

    Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review. Journal of Developmental Biology. (Marquart JP, Nie Q, Gonzalez T, Jelin AC, Broeckel U, Wagner AJ, Reddi HV)

    Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial. Trauma Surgery & Acute Care Open. (Choron RL, Piplani C, Kuzinar J, Teichman AL, Bargoud C, Sciarretta JD, Smith RN, Hanos D, Afif IN, Beard JH, Dhillon NK, Zhang A, Ghneim M, Devasahayam R, Gunter O, Smith AA, Sun B, Cao CS, Reynolds JK, Hilt LA, Holena DN, Chang G, Jonikas M, Echeverria-Rosario K, Fung NS, Anderson A, Fitzgerald CA, Dumas RP, Levin JH, Trankiem CT, Yoon J, Blank J, Hazelton JP, McLaughlin CJ, Al-Aref R, Kirsch JM, Howard DS, Scantling DR, Dellonte K, Vella MA, Hopkins B, Shell C, Udekwu P, Wong EG, Joseph B, Lieberman H, Ramsey WA, Stewart CH, Alvarez C, Berne JD, Nahmias J, Puente I, Patton J, Rakitin I, Perea L, Pulido O, Ahmed H, Keating J, Kodadek LM, Wade J, Reynold H, Schreiber M, Benjamin A, Khan A, Mann LK, Mentzer C, Mousafeiris V, Mulita F, Reid-Gruner S, Sais E, Foote CW, Palacio CH, Argandykov D, Kaafarani H, Bover Manderski MT, Moko L, Narayan M,Seamon M)

    The Impact of Interactions with Nonsurgical Staff on the Surgical Resident Experience in the Nonoperative Clinical Learning Environment: A Qualitative Study. Journal of Surgical Education. (Linn E, Perez J, Winkowski M, Higgins RM, Goldblatt MI, Hooyer K, Dream S)

    Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children’s Oncology Group Bone Tumor Committee Consensus Statement. Journal of the National Comprehensive Cancer Network. (Dietz MS, Al-Ibraheemi A, Davis JL, Hawkins CM, Craig BT, Dasgupta R, Geller DS, Shulman DS, Cohen-Gogo S, Gupta A, Whiteway SL, Slotkin EK, Heske CM, Ahmed SK, Indelicato DJ, Albert CM, Montgomery N, Sandberg JK, Grier HE, Krailo M, Isakoff MS, Rubin E, Lawlor ER, DuBois SG, Mascarenhas L, Grohar PJ, Binitie O, Reed D, Janeway K, Roberts RD, Bailey KM)

    Practical Guide to the Use of AI-Enabled Analytics in Research. JAMA Surgery. (Kothari AN, Kaji AH, Melton GB)

    Unmasking the Environmental Costs of In-Person General Surgery Residency Interviews. Journal of Surgical Education. (Bello RJ, Love E, Peterson KJ, Wagner CL, Reminick JI, Higgins RM)

     
     

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