On The Cutting Edge | August 2023

August 18, 2023

Award Announcements!

In Case You Missed It

The Advanced Research Projects Agency for Health (ARPA-H) has announced “Proposer’s Day” ahead of a forthcoming Broad Agency Announcement (BAA). The BAA is scheduled to be released at the end of August for their new Precision Surgical Interventions (PSI) Program. Proposer’s Day will take place Thursday, Sept. 7 from 9:00 a.m. to 5:00 p.m. with in-person and virtual registration options available. Registration for the event closes Aug. 28 at 11:00 a.m.
Mentorship Database: The Division of Research is implementing initiatives to organize the process of matching research residents and medical students with faculty members for research opportunities. If you are a faculty member interested in mentoring a medical student and/or a resident, please fill out this Qualtrics survey: Survey
NIH Scientific Data Sharing Website: Whether you are involved in an NIH-funded project and want to understand which sharing policies apply to your research and how to comply, or you are a researcher looking to access scientific data from NIH-affiliated repositories, this site is for you. | More information
Grant Writing Club: Designed for anyone in the grant writing process, provides peer feedback on grants prior to or after to submission. Meets Tuesdays evenings at 5:30 PM, quarterly in the HUB6520/virtually. Participants should send a draft of their grant 1-2 weeks prior to the meeting for dissemination to peer reviewers. The club is highly interactive and participants are required to review and/or submit. Please email Rachel Morris , MD if you are interested in participating.
Department of Surgery Intranet Site: Cultural Complications/Grand Rounds/Quality Minute presentations, Surgery Sparks of Gratitude, Global Surgical Programs, Finance/Reimbursement links, DOS Phone list, and resources for logos/fonts/templates. | More Information
Abstract Deadlines and Meeting List: List will be updated each month | More Information

SurPASS Tip of the Month

Sample Applications - NIH

If you are new to writing grant applications, sometimes seeing how someone else has presented their idea can help as you are developing your own application. With the gracious permission of successful investigators, some institutes have provided samples of funded R01, R03, R15, R21, SBIR/STTR, K, and F applications, sharing plans, leadership plans, and more. They have even provided sample summary statements so you can know what to expect to receive as the outcome of the review of your application.

When referencing these resources, it is important to remember:

Proceed with caution – These applications were developed using the forms and instructions that were in effect at the time of their submission and may not apply to the funding opportunity to which you are responding. Follow current application instructions and requirements included in the funding opportunity carefully.
Different strokes – The best way to present your science may differ substantially from the approach taken by those who wrote the example applications. Seek feedback on your draft application from mentors and others.
Don’t be afraid to reach out – Talk to an NIH program officer in your area of science for advice about the best type of grant program and the Institute or Center that might be interested in your idea.
Get scrappy – Samples are not available for all grant programs. Many programs have common elements and the available samples can still provide helpful information.

Any questions? Contact Lynn Cummings, Grants Operations Coordinator, lcummings@mcw.edu

Clinical Research Tip of the Month

Your Trials are Now on the Froedtert Study Information Portal (SIP)

The Froedtert Study Information Portal for non-cancer trials is now live. Clinical trial information from active trials in OnCore is pulled to the Froedtert website to provide a patient-facing portal of available clinical trial opportunities, organized by category. It is important to update the status of trials in OnCore so that the information on the Froedtert SIP remains current.

More information can be found here.

Get Ready! The eBridge Agreements Module Goes Live This Month

The eBridge Agreements module will go live on August 26, 2023. This new module in eBridge will serve as the enterprise system solution for the routing, negotiation, execution, and maintenance of incoming and outgoing Confidentiality Disclosure Agreements (CDAs), Material Transfer Agreements (MTAs), and Data Use Agreements (DUAs). The new module will leverage users’ existing knowledge of eBridge, streamline, automate, and centralize the review and execution process, and enhance transparency.

To create a new CDA, MTA, DUA, or MDA in eBridge, follow the steps below:

Log into eBridge.
From the left column, select New Agreement.
In the Agreement SmartForm, respond to all questions.
On the Agreement Upload page, carefully select the appropriate agreement type. This response determines the next set of pages and questions.
Click on the Question Mark Icon to open Help Text.
Upload attachments as required by selecting Add.
Select Continue to complete the SmartForm one page at a time.
When all pages are complete, select Finish to return to the agreement workspace.
From the left column, select Submit to initiate the review process.

GRANT$ Alert

NIH High-Risk, High-Reward Funding Opportunities
See link more info on each opportunity
Due dates in mid-August and early September 2023

This program supports projects with highly innovative research with the potential for broad impact. There are 4 opportunities currently open.

Elsa U. Pardee Foundation Grant
No limit on funding, up to 1 year
GCO deadline: August 24, 2023
Application due: August 31, 2023

The Foundation funds projects which will allow establishment of capabilities of new cancer researchers, or new cancer approaches by established cancer researchers. It is anticipated that this early stage funding by the Foundation may lead to subsequent and expanded support using government agency funding. Project relevance to cancer detection, treatment, or cure should be clearly identified.

AHW MCW-Led Seed Grants
$50,000 for 1 year
Share draft app with AHW: August 28, 2023
GCO deadline: N/A
Application due: September 11, 2023

For MCW faculty to develop new approaches and methodologies, test innovative ideas, and foster greater collaboration to address Wisconsin’s leading health challenges. Successful seed grants will build a foundation for future research and healthcare provider workforce development endeavors beyond the project period.

ACS-IRG Pilot Awards
$40,000 for 1 year
LOI due: September 1, 2023
Application due: October 1, 2023

Junior faculty establishing cancer research programs can apply for funding.

CTSI PTCS Methodological Innovation Award
$25,000 for 1 year
LOI due: October 31, 2023
Application due: January 8, 2024

Applications should adhere to the principles of translational science. Proposals must be inter-institutional and Lead PI must be from MCW.

Mellowes Center Mini-Grants - Sequencing, Bioinformatics, and Analysis
18 hours of Mellowes Center bioinformatics analytics services
Up to 10 eligible projects will be funded annually

Small-scale research projects will receive 18 hours of Mellowes Center bioinformatics analytics services.

AHW MCW-Led Learning Event Support Funding
$5,000 per learning event
Application accepted until December 31, 2023 as long as funding remains available

Rolling first-come, first serve basis.

Herma Heart Institute Seed Money
$10,000 one-time request
Proposal due in eBridge: N/A
Application due: Reviewed quarterly

Must have an HHI faculty member as the PI or co-PI.

Abstracts Alert

Wisconsin Surgical Society (WSS) Annual Conference
November 3-4, 2023 | Kohler, WI
Abstract deadline: September 3, 2023

Surgeons, students, residents, advanced practice practitioners, nurses, and researchers are all welcome to submit abstracts related to basic science, clinical, and health services research; quality improvement projects; education, policy, and advocacy initiatives; interesting case reports; and any other surgery-related topic you wish to share.
You may submit more than one abstract, but only one will be accepted for presentation. You may be a co-author or senior author on an unlimited number of abstracts.
All abstracts must be sponsored by a WSS member.

Western Trauma Association (WTA) Annual Meeting
February 25-March 1, 2024 | Snowmass, CO
Abstract deadline: September 4, 2023

Abstract Blinding: Abstracts must be blinded, meaning any references to authors or institutions should be removed from the abstract title, content and attachments. You must ensure that your abstract is blinded and does not reveal anything about you or your institution. Abstracts that are not blinded will be disqualified.
Abstract Content: Please structure your abstract using the following headings: Introduction, Methods, Results, Conclusion.
Attachments: Only one attachment per abstract may be submitted. Files must be in .jpg format and legible and fit in the parameters of the above-mentioned template along with your abstract content.
Abstract Sponsor: All abstracts must have a WTA Member Sponsor.

Society for Clinical Vascular Surgery (SCVS) Annual Symposium
March 16-20, 2024 | Scottsdale, AZ
Abstract deadline: September 5, 2023

Collaboration Abstract Category:
3 or more SCVS members
Original abstract
Encourage multi-institution experiences
Priority will be given to papers not derived from large national databases
Case Report Submission Categories Include:
Abdominal Aortic
Thoracic Aortic
Peripheral & Other
Venous & Dialysis
Video Submission Categories Include:
"How I Do It" videos about common vascular procedures that illustrate technique
Unique, Interesting and Rare Vascular Case Videos

Vascular and Endovascular Surgery Society (VESS) 2024 Annual Winter Meeting
January 18-21, 2024 | Sun Valley, ID
Abstract deadline: September 6, 2023

Submissions Categories: Standard papers, Rapid fire presentations, Case reports, Video case reports

Society of Interventional Radiology (SIR) Annual Scientific Meeting
March 23-28, 2023 | Salt Lake City, UT
Abstract deadline: September 21, 2023

Original scientific research: A structured abstract is required and should be organized into the following four paragraphs:
Purpose
Materials and methods
Results
Conclusions
Educational exhibit: Intended for educational exhibits that highlight a technique, concept or subject, rather than hypothesis-driven research. The material in this category is unsuitable for scientific abstract presentation. Examples include a review of a topic, "how-to" demonstrations and pictorial essays. A structured, 4-part abstract is required with the format:
Learning objectives
Background
Clinical findings/procedure details
Conclusion or teaching points

Department of Surgery Recent Publications

Severity of Prior COVID-19 is Associated with Postoperative Outcomes Following Major Inpatient Surgery. Annals of Surgery. (Verhagen NB, SenthilKumar G, Jaraczewski T, Koerber NK, Merrill JR, Flitcroft MA, Szabo A, Banerjee A, Yang X, Taylor BW, Figueroa Castro CE, Yen TWF, Clarke CN, Lauer K, Pfeifer KJ, Gould JC, Kothari AN)

Association of Rural Residence With Surgical Outcomes Among Infants at US Children's Hospitals. Hospital Pediatrics. (Georgeades C, Vacek J, Thurm C, Hall M, Rangel S, Minneci PC, Oldham K, Van Arendonk KJ)

Shared Decision-Making in the Surgical Sciences. JAMA Surgery. (Hawkins AT, Fayanju OM, Maduekwe UN)

Frequent upregulation of HER2 protein in hormone-receptor-positive HER2-negative breast cancer after short-term neoadjuvant endocrine therapy. Breast Cancer Research & Treatment. (Chaudhary LN, Jorns JM, Sun Y, Cheng YC, Kamaraju S, Burfeind J, Gonyo MB, Kong AL, Patten C, Yen T, Cortina CS, Carson E, Johnson N, Bergom C, Tsaih SW, Banerjee A, Wang Y, Chervoneva I, Weil E, Chitambar CR, Rui H)

National Trends in "Going Flat" After Mastectomy. Annals of Surgical Oncology. (Johnson MK, Cortina CS, Hsu TL, Huang S, Frebault J, Huang CC, Kong AL)

Supporting the right ventricle in postcardiotomy renal dysfunction: A case series. Clinical Case Reports. (Sow M, Seadler BD, Chandratre SR, Koratala A, Carlson SF, Joyce LD, Kohmoto T, Durham LA, Joyce DL)

Predictors of initial management failure in traumatic hemothorax: A prospective multicenter cohort analysis. Surgery. (Beyer CA, Byrne JP, Moore SA, McLauchlan NR, Rezende-Neto JB, Schroeppel TJ, Dodgion C, Inaba K, Seamon MJ, Cannon JW)

Changing Landscape of Routine Pediatric Surgery for Rural and Urban Children: A Report from the Child Health Evaluation of Surgical Services (CHESS) Group. Annals of Surgery. (Gadepalli SK, Leraas HJ, Flynn-O'Brien KT, Van Arendonk KJ, Hall M, Tracy ET, Ricca R, Goldin AB, Ehrlich PF)

Management of abdominal wall hernias in patients with severe obesity. Surgical Endoscopy. (Ghanem OM, Orenstein S, Lloyd SJ, Andalib A, Race A, Burt HA, Husain F, Goldblatt M, Kroh M)

Management of complicated diaphragmatic hernia in the acute setting: a WSES position paper. [Review]. World Journal Of Emergency Surgery. (Giuffrida M, Perrone G, Abu-Zidan F, Agnoletti V, Ansaloni L, Baiocchi GL, Bendinelli C, Biffl WL, Bonavina L, Bravi F, Carcoforo P, Ceresoli M, Chichom-Mefire A, Coccolini F, Coimbra R, de'Angelis N, de Moya M, De Simone B, Di Saverio S, Fraga GP, Galante J, Ivatury R, Kashuk J, Kelly MD, Kirkpatrick AW, Kluger Y, Koike K, Leppaniemi A, Maier RV, Moore EE, Peitzmann A, Sakakushev B, Sartelli M, Sugrue M, Tian BWCA, Broek RT, Vallicelli C, Wani I, Weber DG, Docimo G, Catena F)

Isolation and survival: The impact of local and MSA isolation on survival among non-Hispanic Black women diagnosed with breast cancer in the United States using a SEER-Medicare cohort. Health & Place. (Canales B, Laud PW, Tarima S, Zhou Y, Bikomeye JC, McGinley EL, Yen TWF, Bemanian A, Beyer KMM)

Facility type is associated with improved perioperative and oncologic outcomes after minimally invasive surgery for pancreatic cancer. HPB. (Servin-Rojas M, Shafique N, Sell NM, Gamblin TC, Qadan M)

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