The leading cause of death, globally, is heart disease. So when cholesterol-lowering drugs called statins came along with the promise of cutting the risk of a heart attack and stroke by a third, doctors were over the moon. Some even suggested they should be added to the water supply.

Initially, the drugs were given to people who’d had a heart attack or stroke, to stop them from having a second “event” (secondary prevention). But they were soon also prescribed for people at risk of cardiovascular disease (primary prevention). And, over the past three decades, the group deemed “at risk” has grown and grown. The author of a new systematic review suggests that it has grown too much, with many people receiving little benefit from taking the pills.

Russia’s bloody invasion continues, with hints of how Putin may aim to further destabilise Ukraine through the creation of a patchwork of self-proclaimed statelets. And have you ever wondered what the carbon footprint of a T-shirt is? You’ll be horrified when you find out.

Clint Witchalls

Health + Medicine Editor (UK edition)

roger ashford/Shutterstock

Benefits of statins may have been overstated – new study

Paula Byrne, RCSI University of Medicine and Health Sciences

New review suggests many don’t benefit massively from taking a daily statin.

Kherson: occupied but defiant. Olexander Scherba via Twitter

Ukraine: how Putin could try to split the country into regional puppet governments

Stefan Wolff, University of Birmingham; Tatyana Malyarenko, National University Odesa Law Academy

Russia’s playbook for taking control of the Donbas and now Kherson province could be used beyond Ukraine.

Well travelled… Shutterstock

What your T-shirt reveals about ‘carbon colonialism’ and the global economy’s vast hidden emissions

Laurie Parsons, Royal Holloway University of London

Your T-shirt may have travelled one-and-a-half times round the world to reach you.

Ukraine invasion

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