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March 20, 2026 T1D Week in Review (WiR): Curating the scientific conversation in Type 1 Diabetes Th1nkTanks next week Virtual talks on the latest T1D papers and science Basic Science & Translational Papers Format update: Preprints located at the end of each section Efficient control of enterochromaffin versus islet differentiation from human pluripotent stem cell-derived pancreatic progenitors3/18/26Role of small intronic RNAs in the crosstalk between immune cells and β-cells during T1D development3/17/26Selenium-loaded sustained-release schizophyllan alleviates pancreatic and pulmonary inflammatory damage in T1D by modulating gut microbiota and T cell balance3/14/26Human Alpha Cell Dysfunction in Diabetes(Thesis)3/1/26Quality control strategy for differentiating induced pluripotent stem cells into pancreatic β-cells before transplantation3/11/26β-Cell-Derived Extracellular Vesicles Boost β-Cell Functionality in Human Pancreatic Islets3/17/26Design, Synthesis, and Characterization of Prodrugs of Sulfonamide TLR4 Signaling Inhibitor TAK-242 (Resatorvid)3/16/26Sex-Dependent Diabetes Impact of Acute Grp78 Deletion in β-Cells of Adult Mice3/12/26Proteomic analyses of human islets reveal potential markers of β-cell dysfunction during prediabetes3/19/26Human decellularized extracellular matrix from adipose tissue is a permissive microenvironment for pancreatic organoids generation3/12/26Clinical Papers Fulminant type 1 diabetes with high-titer anti-glutamic acid decarboxylase antibodies: Likely rapid progression from stage 2 to 33/17/26Long-term efficacy and safety of Control-IQ technology in younger children with T1D in Italy (2020–2023)3/11/26Highly Uncontrolled Cardiovascular Risk in Emerging Adults With Paediatric-Onset Type 1 Diabetes-A Cross-Sectional Analysis From the Diabetes Prospective Follow-Up Reg...3/16/26Cardiovascular risk equations in type 1 diabetes:from generic models to personalized prediction3/13/26Type 1 Diabetes and Incident Dementia (medRxiv 2025)3/18/26The glycaemic response to morning fasted resistance exercise is more consistent than the response to afternoon fed resistance exercise for T1D adults3/14/26Salivary microbiota signatures of periodontitis are associated with CGM-derived short-term glycaemic control in adults with T1D: a pilot study3/12/26Early Implementation Insights from a Community-Integrated Care Model to Strengthen Type 1 Diabetes Management in Rural Gujarat3/9/26Epigenetic alterations in type 1 diabetes and their association with poor glycemic control: the SED1-EPI substudy3/13/26Progression from Stage 1 to Stage 3 Type 1 Diabetes Characterized by Hypoglycemia3/12/26Hypercholesterolemia and Lipid-Lowering Therapy in Children and Adolescents With Type 1 Diabetes: Do We Implement Current Guidelines?3/17/26Potential years of life lost and factors associated with different causes of death in type 1 diabetes in Finland3/19/26Associations between retinal microvasculature and cognition in middle-aged adults withT1D without overt neurological symptoms3/16/26Improving glycaemic outcomes with subsidised access to diabetes technology in a young adult population with type 1 diabetes3/17/26Screening for diabetes mellitus type 1 in the pediatric general population: an ethical analysis3/13/26Inhaled Technosphere Insulin Reduces Postmeal Glucose Excursion in Youth Living with Type 1 Diabetes3/16/26Glucagon-like peptide-1 receptor agonists for major cardiovascular and kidney outcomes in T1D3/19/26Shrunken Pore Syndrome and Risk of Cardiovascular Disease and All-Cause Mortality in Individuals With Type 1 Diabetes With and Without Albuminuria3/17/26Dementia Risk in Type 1 and 2 Diabetes: A Nationwide Population-Based Comparison3/19/26Beyond Glucose: A Brain Energy Bottleneck Hypothesis for Multi-Energy Substrates in Hypoglycaemia Rescue3/16/26Cost-Effectiveness of Automated Insulin Delivery Systems in Paediatrics, T1D and T2D Adults Across Four Nordic Countries3/19/26Detection of pancreatic beta cell mass in vivo in humans: studies in individuals with long-standing type 1 diabetes and in individuals with obesity3/18/26T1D Data, -Omics, CGM, Tools The Virtual DCCT #4: Relationship of HbA1c and Continuous Glucose Monitoring Metrics with Severe Hypoglycemic Events3/16/26Causal Mediation Pathways in Continuous Postprandial Glucose Monitoring for Type 1 Diabetes Patients3/17/26Application of spectral flow cytometry for comprehensive detection of immune metabolism in patient-derived microsamples3/16/26mRNA-based COVID-19 Vaccination and Risk of Autoimmune Diseases in the Pediatric Population3/12/26The prevalence of autoimmune diseases in antibody negative type 1 diabetes mellitus3/16/26A Four-Variant T1D Genetic Risk Score to Classify Type 1 and Monogenic Diabetes in Chinese Patients3/19/26Protocol to assess calcium signaling in response to metabolic alterations by flow cytometry and live-cell imaging3/19/26The Potential Association of the ACE and TCF7L2 Genetic Polymorphisms with Predisposition of Type 1 Diabetes Mellitus3/9/26Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits3/13/26Developing and Evaluating a Natural Language Processing Algorithm to Detect Insulin Pump and CGM Use in Electronic Health Records2/15/26Lessons from Other Diseases Preclinical efficacy and safety assessment of engineered regulatory T cells for treatment of IPEX and other autoimmune disorders3/13/26Unimolecular GLP-1/Apelin Hybrid Peptides Cause Prominent Appetite Suppression, Enhancing Insulin Secretion, β Survival and Glycaemic Regulation3/16/26In vivo site-specific engineering to reprogram T cells3/18/26Insulin resistance prediction from wearables and routine blood biomarkers3/16/26New Insights into the Relationship Between Microplastics and Diabetes from the Perspective of the Gut–Liver Axis and Macrophage Regulation3/10/26Mitochondrial dysfunction drives natural killer cell dysfunction in systemic lupus erythematosusWeight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans3/17/26To β or not to β: think zinc (again)!3/16/26Gut-derived hyodeoxycholate reprograms the spleen–eye immunometabolic axis to suppress autoimmune uveitis3/11/26Genome-wide cell type-specific and sex-specific transcriptional dysregulation in the islet of Langerhans underlies islet dysfunction in Down syndrome-related diabetes3/16/26Systems Biology of Metabolic Dysregulation in Ankylosing Spondylitis Using scRNA-Seq Data3/17/26Metabolic polygenic risk scores for prediction of obesity, type 2 diabetes, and related morbidities3/16/26Microglia: Replacing the immune system of the brain3/11/26When Central Tolerance Fails: Thymic Malignancies at the Intersection of Cancer Immunity and Autoimmunity2/26/26Systemic neoantigen-specific T cells reveal central determinants of PD-(L)1 blockade efficacy3/12/26Reviews & Op-eds An international consensus on screening and monitoring early-stage type 1 diabetes: A roadmap to European implementation3/11/26Artificial Intelligence in Type 1 Diabetes Management: A Scoping Review of Randomised Controlled Trials3/19/26Βeta-Cells: Stress, Identity, Failure and Diabetes3/6/26Sleep your way to better metabolic health3/12/26PhDs are turning to side hustles to make ends meet, finds Nature poll3/16/26Efficacy and Management of Automated Insulin Delivery Systems Perioperatively in Type 1 Diabetes – A Scoping Review3/11/26Type 5 diabetes mellitus: nutritional-imprinted β-cell insufficiency, diagnostic gaps, and emerging therapeutic strategies3/15/26RNA modifications in gene regulation: Functions and pathways3/19/26NIH pivots away from agency-directed science3/17/26Cardiovascular risk equations in type 1 diabetes: from generic models to personalized prediction3/13/26The use of diabetes technology under aviation conditions: A systematic review of human and in-vitro studies and future considerations1/23/26Thymus health is a predictor of lifelong well-being and immunotherapy effectiveness3/18/26Scientific Publishing: Rethinking how research is reviewed and published3/17/26NEW On Demand Th1nk Tanks Youtube library of T1D talks Business News Upcoming conferences/meetings |
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