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January 2023 Newsletter

Elena Sturman

MESSAGE FROM THE PRESIDENT

Dear Readers,

In 2022, TGF made important strides in our research and education initiatives. We’re ringing in the new year with another new webinar for patients, a discussion and Q&A on lifestyle recommendations for glaucoma with Dr. Aakriti Shukla of Columbia University. Join us live on January 4 or watch the recording on our website.

With glaucoma still the leading cause of preventative blindness, increasing awareness remains critical. January is Glaucoma Awareness Month. We urge you and your family to heed its call and make an appointment to have your eyes examined. Early diagnosis and ongoing treatment can save your sight.

To spread this message, we have placed several bus shelter posters in Manhattan, Brooklyn, and Queens, a public service announcement on 1010WINS Radio, a billboard in Jackson Heights, and a broad campaign on social media. We are also excited to announce that on January 19, in partnership with the STEM Institute (CCNY), we are launching an innovative pilot program to educate young people about glaucoma.  We look forward to telling you more about this project as it progresses.

In 2021, we announced that the Foundation, in partnership with Research to Prevent Blindness (RPB), is granting fellowships to young physicians specializing in glaucoma. Three doctors were awarded the fellowship last month and you can read about them in this newsletter.  

We have also continued to expand our Board of Directors. Our newest members are Annette Grollman, president of Oestreicher Medical Communications, and Barbara Hearst, a former Board member who rejoined us in December. We are grateful for their dedication and enthusiasm for our mission.

In closing, we thank you for being a newsletter reader and a supporter of TGF’s efforts.

In closing, we thank you for being a newsletter reader and a supporter of TGF’s efforts. In the year ahead, we look forward to continuing answering questions and addressing subjects of importance to you. If there are topics you would like us to explore in future issues, let us know at info@glaucomafoundation.org.

With all best wishes for a happy and healthy New Year, 

Elena Sturman

DOCTOR, I HAVE A QUESTION.
How should I use my eye drops?
Question answered by Aakriti Garg Shukla, MD

Dr. Aakriti Shukla

Dr. Shukla is a board-certified ophthalmologist, fellowship-trained glaucoma specialist, and the Leonard A. Lauder Assistant Professor of Ophthalmology at the Columbia University Irving Medical Center.

Currently, the goal of glaucoma treatment is centered on the prevention of progression, or worsening, of glaucoma. Complementary to this aim and equally important is to help patients maintain their vision-related quality of life, which can be associated with many factors including treatment burden, the extent of glaucoma severity, and other topics beyond the scope of the present discussion.

Lowering the pressure inside the eye is the only known way to prevent the worsening of glaucomatous damage. This is accomplished by eye drop medications, laser procedures in the office, or surgical procedures in the operating room. While medicated eye drops are the option most patients and ophthalmologists choose first, their use is not completely straightforward. Below are common questions regarding eye drops:

How should I get the drop in my eye? It tends to land on my cheek or forehead. My recommendation is to optimally position your body and hand to maximize the chance that the drop will successfully land on your eye. First, lie flat when instilling drops. This could mean laying down on a bed (probably the easiest way) or laying your head back - ensure that your head is completely horizontal - when sitting down. Second, prepare your hand by resting it on the bridge of your nose, forehead, or cheek. Third, gently squeeze the bottle to elicit a drop. In some bottles, this will require a slightly stronger squeeze, while in others, the drop will come out due only to the effect of gravity. Some people find a benefit in pulling down their lower lid to ensure the eye stays open.

The eye drop landed in my eye. What do I do now? I recommend closing your eye for about a minute to ensure the drop is absorbed. One can also press gently on the inner aspect of the eyelid near the nose to prevent systemic absorption of the medication. This is known as nasolacrimal occlusion and is more important for certain eye drops (especially beta-blocking medications such as timolol) than others. Performing this maneuver can also help you avoid an unpleasant taste in your throat after instilling the drop, which sometimes occurs when the drop travels down the canal that connects your eyes, nose, and throat.

No matter what I do, I cannot make the eye drop land on my eye. What are my options? The options for you will be based on what your ophthalmologist recommends, but almost everyone can use an eye drop instillation device. These are available over-the-counter at most pharmacies and online. Studies on these devices have mixed results, although most have shown that they help with successful drop instillation, are associated with less bottle tip contact on the periocular or ocular surface, and allow for the release of only one drop from the bottle compared to traditional techniques. Most patients report that these devices are relatively easy to use.

Depending on the type of glaucoma you have and other factors specific to your condition, alternatives to eye drops include selective laser trabeculoplasty, an office-based laser procedure, and incisional glaucoma surgery in the operating room.

How many drops from each bottle do I need to get into my eye? You need just one drop from each bottle into the eye at a given time. Some glaucoma medications are dosed once a day, while others are dosed as frequently as four times a day. Regardless of the frequency, you need no more than one drop at each dosing. There is some evidence that you need less than one drop at a time for it to have a sufficient pressure-lowering effect. Devices that use innovative techniques to deliver less than a drop of medications, which may make medication bottles last longer, are being studied. While their efficacy is still being tested, the results are quite promising. For patients taking preservative-free eye drops, the drops come in individual vials, and are intended for one-time use only.  One week of vials come in a foil pouch, and should be stored in pouch until use. Once pouch is opened, the vials should be used within 15 days, or discarded.

How long do I need to wait between various types of eye medications? Many patients are on more than one type of eye drop. If using more than one type of medication at a time, it is important to separate the different medications by 5 minutes. Some of my patients say that they wait for an hour or two between multiple medications. This is also fine to do, but if using three types of medication, it could mean that you spend your entire evening putting in eye drops. This is not practical or necessary. It is also not necessary to use the drops in a specific order.

Do the eye drops have side effects? Glaucoma medications can have side effects that vary from ocular surface discomfort (often manifests as a sandy feeling in the eye) to changes in your heart rate. These are specific to each class of medication and it is important to inform your ophthalmologist immediately if you notice a change in your eye or systemic health. 

JANUARY IS GLAUCOMA AWARENESS MONTH

Start off the New Year by scheduling an appointment for a comprehensive eye exam. It could save your sight.  

Glaucoma, the silent thief of sight, is a group of eye diseases that affect the optic nerve and permanently impair your vision. It is the leading cause of preventative blindness, affecting as many as 80 million people around the world. The number of glaucoma patients is estimated to increase 40% to almost 112 million by 2040.

Many people are unaware of their risk, and at least half of those with glaucoma experience no symptoms until significant damage and loss of vision has occurred. Right now, as many as 1.5 million Americans are unaware that the disease is silently damaging their optic nerves.

Glaucoma can run in families, and it disproportionately affects people of African and Latin descent. Although most patients are diagnosed after the age of 40, glaucoma can arise at birth or at any time of life.

TGF urges you to protect your vision. Make a comprehensive eye exam a part of the annual healthcare for yourself and your loved ones

 High-risk factors for glaucoma include:

People over the age of 40. 
While glaucoma can develop in younger patients, it occurs more frequently as we get older.

People who have a family history of glaucoma. 
Glaucoma appears to run in families. The tendency for developing glaucoma may be inherited. However, just because someone in your family has glaucoma does not mean that you will necessarily develop the disease.

People with abnormally high intraocular pressure (IOP). 
High IOP is the most important risk factor for glaucomatous damage.

People of African, Hispanic, Latino, and Asian descent. 
People with African and Latino ancestry have a greater tendency for developing primary open-angle glaucoma than do people of other races. People of Asian descent are more prone to develop angle-closure glaucoma and normal-tension glaucoma.

People who have:
– Diabetes
– Myopia (nearsightedness)
– Regular, long-term steroid/cortisone use
– A previous eye injury
– Extremely high or low blood pressure
– Thin central corneas

Comprehensive eye exams are recommended for:

Everyone under 40: every three to four years.

Individuals under 40 with one of the above risk factors: every one-and-a-half to two years.

Everyone 40 years or older: every one-and a-half to two years.

Everyone 40 years or older with an additional risk factor listed above: annually.

Although there is still no cure, the good news is that glaucoma can be managed if it is detected early. With early diagnosis and medical and/or surgical treatment, most people with glaucoma will not lose their sight.

 
TGF and RPB logos

  Fellowships Support Under-Represented Minorities in Glaucoma Research

Beginning in 2021, TGF and Research to Prevent Blindness (RPB) partnered to provide   fellowships to increase diversity in glaucoma research.   The TGF (sponsored by Patricia Hill) / RPB Fellowships in Glaucoma provide one-year, $10,000 supplemental fellowships targeted to under-represented racial and ethnic minorities, as defined by the NIH, who are fellows in departments of ophthalmology engaged in substantive glaucoma research.  Three new awardees were selected in December.

Clara Maria Colon Garcia-Moliner, MD

Clara Maria Colon Garcia-Moliner, MD
Kresge Eye Institute, Wayne State University

During her residency, Dr. Colon Garcia-Moliner investigated surgical outcomes of her Institute’s minimally invasive glaucoma surgeries (MIGS), specifically looking into the Xen gel stent. In her community at Kresge Eye institute, they found that the success rate for xen gel stents in a predominantly African-American population was less than 50%.  With the aid of this grant, she aims to further evaluate the mechanism of failure in this type of stent.  

Specifically, the funding will be used to acquire specialized stains and access to equipment to histopathologically examine xen gel stents that have been explanted after failure. Funds will also be used to potentially present findings at a major professional meeting.

Dr. William Plum

William Plum, MD
Columbia University  

After Dr. Plum’s family emigrated to the US from Brazil when he was nine, his family’s healthcare, of necessity, took place entirely in the community screening and free clinic setting. These experiences motivated him to investigate the effectiveness of community-based interventions, with the aim of improving the detection and management of glaucoma and other eye diseases in vulnerable populations. Funding from the Glaucoma Foundation will allow him to study a question-based risk assessment at primary care offices as a form of screening for the detection of glaucoma in the community. This grant will fund the study analysis, which will be performed at the Mailman School of Public Health at Columbia University.

Jose Quiroz, MD, PhD

Jose Quiroz, MD, PhD
Icahn School of Medicine at Mount Sinai

A first generation Mexican American, Jose Quiroz received both his MD and PhD in biomedical sciences this year. The focus of his thesis work was developing a viable human antibody treatment for Chikungunya Virus that was derived from human convalescent patients in the Bronx Dominican communities. He aims to use these techniques to better understand the immune response that leads to uveitic glaucoma, specifically to demonstrate a proof-of-concept approach to developing a targeted antibody for uveitic glaucoma pathologies.  If successful, this research would impact sectors of the community which are underrepresented populations.

LIVING WITH GLAUCOMA
Meet Susan Genis

Susan Genis

When we first met Susan Genis in 2009, she had just been diagnosed as “legally blind.” “I probably could have been diagnosed [as legally blind] years earlier based on my reduced visual field from advance glaucoma,” she says; “but that legal determination was an awakening, allowing me to receive all sorts of mobility-oriented help and various devices to make my life easier. I’ve been dealing with vision issues for some 50 years. It all started in my 20s, after years of extreme myopia – first uveitis, then cataracts and glaucoma.“

Recently, we met Susan again. An active 74-year-old New Yorker, she has lost all vision in her left eye and undergone several surgeries in the right -- a stent implant and a partial cornea replacement.

Susan is a former criminal lawyer and yoga instructor, who still teaches yoga to seniors on Zoom. “Since we first met, I have discovered so many activities in the city for people with low vision that I never knew existed. So, in spite of it all, I’m busier and I’m happier.”

She points out that most of the art museums in the city offer a range of free programs for people with low vision – among them MOMA, the Met, the Whitney and Guggenheim museums. “That’s been fantastic.”

“Then I discovered a non-profit organization that does tandem biking for people with disabilities. You just sign up and they match you with a volunteer ‘captain.’ It’s usually a two-hour ride, these days in Central Park – but only when it’ s over 40 degrees and dry. What a feeling of freedom!”

Susan has done the five-borough bike ride. While currently not riding because she’s on the mend from a fractured pelvis, her goal is to do the five-borough ride again next May.

“The captain in front does the steering and changes the gears and handles the brakes. The captain serves as our eyes and controls the ride. But we both pedal so you have to be in synch. The essence of tandem biking is communications. I like going fast. It’s a nice workout”.

For the last four years Susan has been a member of the chorus at the FMDG Music School, which is specifically for people with visual impairments. “They accommodate with large print music, braille music, and audio cassettes. “We recently performed at the Met Museum’s Cloisters, and there’s a law firm that supported a performance in their office building’s lobby. In the spring, the chorus is scheduled to perform at the Met Museum – a combined project of music and art.”

She’s also a longtime steering committee member of the Glaucoma Support and Education Group, which meets monthly, now on Zoom, for a Saturday lecture by leading glaucoma experts to learn about and discuss innovative new approaches to glaucoma diagnosis and how to manage the disease.

“I don’t think I could live outside New York because I know the city, and there are so many options here – buses, subways, taxis. Mostly, public transportation has served me just fine. But since my accident, I haven’t really taken the subway, even though I find in some ways it is easier because I know the stops. At the moment, I’m using the Access- a-Ride service and taxis more. I love that a lot of the newer buses announce the stops and I find that most people are really helpful when I need assistance.

I’ve lived in my apartment for over 40 years so I know it and I know where things are. As I cannot read print of any kind, I rely completely on magnifying glasses and have several devices. I have a large screen computer and I have everything magnified. And when I use my iPhone, I dictate into it. I have the Be My Eyes app, and while I don’t yet rely on those things, sometimes I’ll ask – ‘what does this say,’ or, ‘what street is this.’ I have different canes – they give me a sense of where I’m at.

“Considering it all, I’m doing really well,” Susan says. Here are the websites for some of the activities Susan has suggested in New York.

FMDG Music School—for children and adults with visual impairments https://fmdgmusicschool.org

InTandem Cycling—for anyone who is unable to ride a bike alone https://www.intandembike.org

NY Public Library Services for Blind and Visually Impaired https://nlsbard.loc.gov/login//NLS

Andrew Heiskill Library Braille and Talking Book Library https://www.nypl.org/locations/heiskell

Glaucoma Support and Education Group
gseg@glaucomasupport.org

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