Brain health and neuroscience updates

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A purple swoosh of cells runs down the left hand side of an event poster for Glial and Neuronal Biology of the Aging Brain Oct. 5-6

Congratulations Emery N. Brown!

 

Innovative neuroscientist, statistician and anesthesiologist earns National Medal of Science

A photoillustration shows Emery Brown with an enlarged photo of the National Medal of Science to his left.

Emery N. Brown, Edward Hood Taplin Professor of Medical Engineering and Computational Neuroscience in The Picower Institute for Learning and Memory at MIT, has won the National Medical of Science, the nation’s highest recognition for scientists and engineers, the White House announced Jan. 3. Story continues>>

 

Picower Research & Discoveries

 

Study suggests how the brain, with sleep, learns meaningful maps of spaces

Two panels show clusters of dots of various colors. The cluster on the left is round. The cluster on the right is shaped like a Y.

Place cells are well known to encode individual locations, but stitching together a “cognitive map” of a whole environment requires a broader ensemble of cells, aided by sleep, to build a richer network over several days.

A study in mice by Picower Insitute neuroscientists provides new evidence for how the brain forms cohesive cognitive maps of whole spaces and highlights the critical importance of sleep for the process. Story continues>>

 

Open technology platform enables new versatility for neuroscience research with more naturalistic behavior

A cartoon shows a mouse wearing electronics on its head, leaping from a lower part of a 3-dimensional landscape to a higher point.

System developed by MIT and Open Ephys team provides a fast, light, standardized means for combining multiple instruments with minimal hindrance of lab mouse mobility.

Individual technologies for recording and controlling neural activity in mice have each advanced rapidly but the potential of easily mixing and matching them to conduct more sophisticated experiments, all while enabling the most natural behavior possible, has been difficult to realize. To empower a new generation of neuroscience experiments, engineers and scientists at MIT and the Open Ephys cooperative have developed a new standardized, open-source hardware and software platform. Story continues>>

 

New autism research projects represent a broad range of approaches to achieving a shared goal

Five professors sit in a row on the stage of an auditorium. From left to right they are Ev Fedorenko, Gloria Choi, Chuck Nelson, Earl Miller and Mriganka Sur.

At a symposium of the Simons Center for the Social Brain, six speakers described a diversity of recently launched studies aimed at improving understanding of the autistic brain.

From studies of the connections between neurons, to interactions between the nervous and immune systems, to the complex ways in which people understand not just language but also the unspoken nuances of conversation, new research projects at MIT supported by the Simons Center for the Social Brain are bringing a rich diversity of perspectives to advancing the field’s understanding of autism. Story continues>>

 

Picower People

 

Congratulations new PhDs!

Sebastian Pineda stands behind a silvery curved podium
Max Heinrich stands behind a wooden podium

Two graduate students in Picower Institute labs defended their theses last month and we're proud to call them each doctor!

  • Left - Sebastian Pineda (Heiman Lab): "Single-cell dissection of vulnerable cell types and disease mechanisms across neurodegenerative motor disorders."
  • Right - Max Heinrich (Bear Lab): "Spontaneous activity in the mouse visual cortical slice: biophysical characterization and pathophysiology"
 
 
A certificate from "MIT EHS"

Picower personnel earn safety award

Recognizing the commitment to lab safety indicated by our high compliance with training and inspections, MIT's EHS office gave The Picower Institute an "Excellence Award" Dec. 10. Yay, us!

 

Play the Puzzle: Round 2 of  'Cortex Vortex'

How many words can you make out of seven letters? Can you make words using all 7? Use your cortex and take version 2 of our new game for a spin!

A screenshot of the puzzle, which consists of seven letters in a circle and a background image of a brain
 

In the media

 

Forbes covered Emery Brown's National Medal of Science. Meanwhile in Canada, the CBC devoted a chunk of a recent Quirks and Quarks science podcast to Li-Huei Tsai's research (in which Brown is a collaborator) on potentially treating Alzheimer's disease with 40Hz light and sound. In fact, IEEE Spectrum named the research one of the top 10 biomedical stories of 2024.

An opinion piece in The Guardian on "Brain Rot" quoted Earl Miller. So did The Transmitter, which asked neuroscientists about the value of holding on to unused data. Matt Wilson's research on animal cognition during sleep caught the attention of K9 Magazine, which asked what dogs dream about. And don't worry, cat people, Petful did much the same for cats last spring. Also of note, the new MIT Press book "Longevity Hubs" compiled by MIT AgeLab researchers Joseph Coughlin and Luke Yoquinto, includes an essay by Tsai.

A sleeping boxer dog
A sleeping shortair house cat
 

Tune into Mi Última Neurona

Jessica Chomik-Morales, a graduate student in MIT's Brain and Cognitive Sciences Department, continues her Spanish-language podcast about all things neuroscience: "Mi Última Neurona," co-sponsored by The Picower Institute. Check it out on YouTube and miultimaneurona.com.

A video camera viewfinder shows Jessica Chomik-Morales interviewing a subject.
 
 

Upcoming Events

 

A note about events: Event schedules and details are subject to change. Please check associated links frequently in advance of events that interest you.

 

Save the date for The Aging Brain Initiative Symposium: September 18, 2025

A symposium poster shows three uncaptioned research images in a circular shape and arranged in a vertical stack. The text lists the event speakers Michael Schwartz, Isaac Chiu, Marco Colonna, Jonathan Kipnis, Sarkis Mazmanian, Sara Prescott, Asya Rolls, Beth Stevens and Kevin Tracey.

Join us on Thursday, September 18, 2025 at The Picower Institute for Learning and Memory for a full day of talks and a trainee poster session exploring the neuro-immune axis and the aging brain with the keynote delivered by Michal Schwartz of the Weizmann Institute of Science. Check back for the schedule and registration page soon.

 

Brain and Cognitive Sciences colloquia

  • Feb. 27, Li-Huei Tsai,  The Picower Institute at MIT
  • April 17, Ivan Soltesz, Stanford University
  • May 8, Joni Wallis, UC Berkeley

All colloquia begin at 4 p.m. in Singleton Auditorium, MIT Building 46

 

Aging Brain Initiative Seminars

  • Feb. 24, Ronald DePinho, MD Anderson
  • May 12, Andrew Yoo, Washington University

Seminars begin at 4 p.m. in the Picower Seminar Room, MIT Building 46

 

Special Seminar

Feb. 28, Nako Nakatsuka, EPFL at 4 p.m. in the Picower Seminar Room, MIT Building 46.

 
 
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