Welcome to YHEC's August 2025 Newsletter

Read on to find out about all the latest news at YHEC.

Latest News at YHEC

Advancing Cost-Effective Cardiovascular Prevention in Spain

A new publication, co-authored by YHEC's Associate Director, Stuart Mealing, and Senior Research Consultant, Amy Dymond, offers critical research into the cost-effectiveness of the CV-Polypill for secondary cardiovascular prevention in Spain.

Using decision analytic Markov modelling methodology, the paper demonstrated that the CV-Polypill is a dominant strategy from the Spanish healthcare perspective. This innovative approach delivers improved health outcomes and reduces costs over the time horizon. These robust findings, grounded in data from the SECURE trial and reinforced by sensitivity analyses, underscore the intervention's economic and clinical benefits.

This publication, a result of a Europe-wide collaboration of experts, is now available in The Lancet Regional Health – Europe.

Read the full article and contact us to discuss how YHEC can help with your project.

YHEC's experts share insights at the RSS International Conference

We're delighted that YHEC will have a strong presence at the Royal Statistical Society conference this September. We have three podium presentations, showcasing our latest research in health economics and statistical modelling.

Joe Moss will be presenting 'From Data to Decisions: Leveraging Statistics to Improve Healthcare Decision-Making,' exploring how regression modelling can be used in economic modelling to capture disease progression more accurately, giving examples from two case studies.

Erin Barker will discuss 'Investigating Input Correlation in Probabilistic Sensitivity Analysis (PSA),' explaining the impact of different parameter correlation structures on PSA outputs in an R Shiny model.

Neil Hansell will share 'Recommended Data Standards for Managing and Reporting Missing Utility Data for Health Technology Appraisal,' addressing crucial challenges in handling missing data in cost-effectiveness analyses.

We're incredibly excited for them to contribute to the discussions at RSS 2025.

Contact us if you would like to meet our team.

The cost and carbon footprint of musculoskeletal pain

A new paper, co-authored by Melissa Pegg and team, quantifies the significant cost and carbon footprint of musculoskeletal (MSK) pain management in primary care. Published in the International Journal of Health Planning and Management, the study reveals key variations and identifies pharmacological interventions as a major carbon contributor.

At YHEC, we understand the increasing importance of evaluating not just economic value, but also the environmental impact of healthcare interventions and pathways. Our expertise in health economics consultancy and research can help health organisations, policymakers, and industry stakeholders:

• Conduct robust economic evaluations and cost-effectiveness analyses.
• Assess resource utilisation and its financial and environmental implications.
• Inform policy development aimed at achieving sustainable, high-value care.

Email us to find out more. The full paper is available on our website.

Spotlight on YHEC's Mick Arber

Our latest Meet the Team blog highlights the work of YHEC's Senior Information Specialist, Mick Arber.

With 25+ years in health information and evidence synthesis, Mick brings expertise in rigorous, high-quality literature searching. He explains that information specialists are an integral part of YHEC's Review and Evidence Synthesis Service, and discusses how his work forms the foundations for robust systematic reviews and other projects.

“We’re like detectives - every project is a new puzzle."

Read more.

More news

13 members of the YHEC team standing in a line at Knaresborough station.

Donate here

Walking for York Foodbank

YHEC is raising money for York Foodbank, a charity which aims to provide three days’ nutritionally balanced emergency food and support to local people in crisis.

The YHEC team braved blisters and hot weather to hike the 21 miles of the Knaresborough Circular and raised over £1,100.

Help us by donating to our fundraising. YHEC will match every pound raised.

Congratulations to Barbara Uzdzinska

YHEC would like to congratulate Barbara Uzdzinska on being promoted to Senior Research Consultant.

Well done Barbara!

Welcome to Rebecca and Simone

We're delighted to welcome Rebecca Watts and Simone Bolton to the YHEC team!

Rebecca will be working as Project Administrator and Simone will be working in the role of Administrator.

Our Latest Publications

Journal of Wound Care

Joe Moss, Principal Statistician at YHEC, is co-author of new research published in the Journal of Wound Care: "Cost-effectiveness of subepidermal moisture measurement to prevent hospital-acquired pressure ulcers".

The study evaluates the economic impact of adding subepidermal moisture measurement (SEM) to current standard of care in hospitals, and concludes that SEM has the potential to reduce costs by improving the effectiveness of pressure ulcer prevention.

Read the full paper.

International Journal of Technology Assessment in Health Care

A recently published paper in the International Journal of Technology Assessment in Health Care delves into the definition and scope of early Health Technology Assessment (HTA).

Co-authored by YHEC Senior Research Consultant, Melissa Pegg, with her colleagues from the Environmental Sustainability in HTA (ESHTA) Working Group, the publication offers valuable insights and suggestions on how early HTA can be leveraged to support the crucial goal of enhancing environmental sustainability in healthcare.

PharmacoEconomics - Open

Research published in PharmacoEconomics - Open demonstrates that continuous remote arrhythmia monitoring with an insertable cardiac monitor (ICM) is a cost-effective addition to the standard of care for high-risk patients with non-ST-elevation myocardial infarction (NSTEMI). The study was co-authored by YHEC's Amy Dymond, Will Green and Erin Barker.

From a UK NHS perspective, this approach offers value, highlighting a promising new option for patient management.

Find out more and read the full paper.

Journal of Vascular Nursing

A new paper, evaluating the implementation of a supervised exercise therapy (SET) service for people with claudication, has been published in the Journal of Vascular Nursing.

Co-authored by YHEC’s Hannah Ross, Nick Hex and Rachael MacDonald, the study reports on a quality improvement project aimed at addressing a longstanding gap in the delivery of SET for patients with peripheral artery disease.

The York Claudication Exercise Service was successfully embedded within the existing care pathway, with promising early results. The findings highlight the feasibility, clinical benefit and economic value of supervised exercise programmes in routine care.

Read more on the YHEC website.

Upcoming Webinars and Online Training Courses

Identifying Economic Evidence for HTA

Health economics evidence is a key element in health services research and particularly in health technology assessments. Identifying economic evidence to inform HTA can involve searching a range of databases and using a variety of strategies. This study day will include a ‘jargon buster’ session on the basics of health economics and economic models. It will also feature presentations about key economics information resources including the CEA Registry, and explorations of options for searching to identify data for economic models.

Wednesday 10 September

Practical Issues in Producing Network Meta-Analyses for HTA

Network meta-analyses (NMAs) are often complex and challenging projects to undertake and involve various planning considerations that are critical for successful delivery. This two-day workshop is offered by experienced reviewers and statisticians from YHEC. It offers an introduction to the practical issues involved in commissioning and performing NMAs for project managers, research commissioners and others new to these techniques.

Tuesday 16 September and Wednesday 17 September

Citation Analysis: Discovering New Uses Within Systematic Reviews

With the introduction of new tools and more access to citation indexes, citation analysis may offer new opportunities for assisting with systematic reviews, particularly reviews of complex questions where searchers may not always be confident that their subject searches are exhaustive. This online workshop will describe some of the new tools and how to use them.

Tuesday 23 September

Public Health Economics and Wider Policy Considerations

This half-day training course will provide an understanding of the principles of modelling public health interventions. The course will also focus on some of the methods and techniques used to consider wider policy considerations in decision making, including health inequalities and environmental sustainability. It will cover what implementation science is and the value it has in optimising the benefit of new healthcare interventions.

Thursday 25 September

How to Build an HTA Dossier

This practical course is ideal for anyone involved in preparing submissions to health technology assessment (HTA) agencies. Gain insights into who the likely stakeholders will be, what makes a compelling dossier and how best to report the data and analyses that are required.

Wednesday 15 October

Find out more and register

Careers at YHEC

Work with us

Are you thinking about a new role? Keep an eye on our YHEC Careers page or subscribe to our mailing list to find out about new vacancies. In addition to the advertised health economics jobs, we are always happy to receive enquiries from modellers, information specialists or systematic reviewers with at least two years’ experience.

Watch our video to find out more about working at YHEC.