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Welcome to the April 2025 edition of the newsletter from the NSCLC Patient Gateway. 

Since our last newsletter in October, we have seen a lot of progress in the non-small cell lung cancer (NSCLC) space across many aspects of patient care—including the FDA approval of subcutaneous (injected) nivolumab for treating metastatic NSCLC. The first treatment for metastatic NSCLC with the NRG1 biomarker was also approved. This approval marks a milestone as the tenth biomarker in NSCLC with a targeted treatment option. In addition to treatment, there is tremendous hope in ongoing research that spans the full spectrum of cancer care. Researchers are working to bring wearables to the NSCLC space along with new treatments for cachexia, the extreme fatigue and weight-loss often associated with advanced NSCLC.

In the treatment of early-stage disease, oncologists and scientists are making headway in understanding the best ways to treat NSCLC perioperatively (before and after surgery). For patients with unresectable, locally advanced NSCLC treated with chemoradiation therapy, adding consolidation therapy with durvalumab, an immune checkpoint inhibitor, reduced the risk of disease progression by 25% compared to placebo in a phase 3 clinical trial.

There is clearly tremendous hope and progress on the horizon for patients living with NSCLC. We must continue to support research studies to maintain this momentum and improve treatment options for patients and their loved ones.

Research News

OncLive
NRG1 Fusions Emerge as New Target of Interest in Lung, Pancreatic Cancers
Published Dec 17, 2024

Oncology Nursing News
FDA OKs Subcutaneous Nivolumab in Advanced/Metastatic Solid Tumors
Published Dec 27, 2024

CURE
Top Lung Cancer Stories in 2024
Published Jan 3, 2025

Oncology Nursing News
Consolidation Durvalumab Improves PFS in Unresectable NSCLC
Published Jan 3, 2025

OncoDaily
Navneet Singh: Expert consensus statement on the peri-operative management of NSCLC
Published Jan 13, 2025

Oncology - CancerNetwork
Ponsegromab Reduces Symptoms Linked to Cancer Cachexia, Elevated GDF-15
Published Jan 15, 2025

OncoDaily
Yvonne Diaz on the hopes and concerns of cancer patients regarding the use of AI wearables – Lung Cancer Europe
Published Jan 15, 2025

Get Connected

You Are Invited!    
Ready to experience an event that’s all about YOU? HOPE Summit is where lung cancer survivors and caregivers come together to connect, learn, and thrive. Think of it as a weekend filled with inspiration, knowledge, and a whole lot of hugs and high-fives. This year's event takes place May 2-4 in Bethesda, MD, and is free to attend. Registration is still open! Learn more.

Join Us for the NSCLC Virtual Meetup
This is an easy way to build your community. On the second Wednesday of each month, you can connect with others who understand what it’s like to live with NSCLC. The next NSCLC Meetup is happening on Wednesday, May 14, at 12 pm ET. Register for free for this virtual meetup to get a confirmation email with details about how to join the virtual meeting. New attendees are always welcome and encouraged to join!

Can’t make it? Don’t worry, there’s a full list of virtual meetups to fit your schedule.

Have You Seen?

Lung Cancer Surgery for Early-Stage NSCLC      
Stephen R. Broderick, MD, MPHS, thoracic surgeon at Johns Hopkins Medicine, joined LUNGevity for an educational webinar on lung cancer surgery. In a session of less than an hour, Dr. Broderick covered the key information about lung cancer surgery. Watch here.

Significant Weight Loss During Treatment   
Losing significant weight and muscle mass during lung cancer treatment is common. However, often these symptoms are not a side effect of treatment. They can be due to a condition called cachexia. Learn more about this condition—including who is at risk for it, how to recognize it, and what can be done to address the symptoms.

ADCs: How Do They Treat Lung Cancer? 
Learn about this exciting new class of treatment for NSCLC from Benjamin Levy, MD, an internationally acclaimed physician-scientist and expert on antibody-drug conjugates (ADCs). In this webinar, Dr. Levy discusses important research in the field and key drugs to be on the lookout for. Watch here.

Integrative Oncology and Lung Cancer: Adding Complementary Therapy 
Have you ever wondered if aromatherapy actually works? Can regular yoga practice be done during lung cancer treatment? The answers to these questions (and more) are being studied by lung cancer experts. Integrative oncology is about how to safely incorporate nutritional supplements and other complementary therapy into your treatment plan. Learn more.

…and there is always so much more to explore on the NSCLC Patient Gateway.

If you were forwarded this email and you’d like to subscribe to this newsletter, you can sign up here.

If you are looking for more LUNGevity Foundation news, check out LUNGevity’s monthly newsletter.

If you need further assistance along your lung cancer journey, please email us at support@lungevity.org. Our team is always here to assist you.

 
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