Welcome to the March 2025 edition of the Rare Mutations and Fusions newsletter from LUNGevity's Patient Gateways. Since our last newsletter in September, we have seen a lot of progress in the lung cancer space—including the US Food and Drug Administration’s (FDA’s) first approval for treating NRG1-positive non-small cell lung cancer (NSCLC) with zenocutuzumab. In addition, the FDA has agreed to expedite the review process for using zongertinib to treat adults with advanced, HER2-positive NSCLC. Meanwhile, other studies are underway to expand the use of trastuzumab deruxtecan to treat NSCLC tumors that have overexpression of HER2. Taletrectinib, an oral drug with central nervous system activity, has also been granted an accelerated review by the FDA for treating advanced ROS1-positive NSCLC. The progress in the lung cancer space for many different types of rare mutations and fusions has been exciting, as exemplified by our advances in treating RET-positive NSCLC. These types of research studies must continue so that patients with lung cancer can get access to the next generation of treatments on the horizon. Research NewsOncLive OncLive ReachMD OncLive CURE Delve Insight Get ConnectedYou Are Invited!
New Hope for Treating RET+ Cancers: A Live Discussion Discover groundbreaking cancer research! Join our Facebook Live event to explore protein degraders, a promising new approach for treating RET-positive cancer. Hear from patient advocates and experts, including Justin Drake, PhD, a leading researcher at the University of Minnesota. Dr. Drake, the 2024 RETpositive/LUNGevity awardee, will explain how these innovative therapies work, offering hope for those with RET-driven cancers. We hope to see you on March 28 at 12-1 pm ET at Facebook.com/LUNGevity. Join Us for the Rare Mutations Virtual Meetup Register for this virtual meetup to get a confirmation email with details about how to join the virtual meeting. New attendees are always welcome and encouraged to join! Can’t make it? Don’t worry, there’s a full list of virtual meetups to fit your schedule. Have You Seen?Brain Mets Basics for NSCLC Significant Weight Loss During Treatment Treatment News for RET+ NSCLC Understanding Clinical Trials: Three-Part Series Part 1: Why Are Clinical Trials Important for Drug Development? Part 3: How Do Drugs Get Approved (and Fast-Tracked) by the FDA? … and there is always so much more to explore on the Rare Mutations & Fusions Patient Gateway. If you were forwarded this email and you’d like to subscribe to this newsletter, you can sign up here. If you are looking for more LUNGevity Foundation news, check out LUNGevity’s monthly newsletter. If you need further assistance along your lung cancer journey, please email us at support@lungevity.org. Our team is always here to assist you. |